Work Experience

  • Todate 2013

    Prof.Dr.

    Near East University, Obstetrics and Gynaecology; veterinary Faculty

  • 2011

    Senior Scientist; Proje Koordinatörü

    Veterinaer Universitaet Wien, Vetsuisse-Faculty University of Zurich, Viyana (Doğum) , Zürich (Anatomi-Histoloji, Moleküler Biyoloji, Sığır Kliniği)Kopenhagen (Büyük hayvan Kliniği)

  • 2014 2011

    Proje koordinatörü; Büyük Hayvan ve Küçük Hayvan Klinik Dersleri, Uygulamalar;

    Veterinaermedizinische Universitaet Wien, Geburtshilfe, Gynaekologie und Andrologie

  • Todate 2008

    Prof.Dr. DAAD Stipendium

    Stiftung Tieraerztliche Fakultaet Hannover, Klinik für Geburtshilfe u. Gynaecology

  • 2011 2008

    Prof.Dr.

    Ankara Üniversitesi, Doğum ve Jinekoloji

  • 2008 2008

    Prof.Dr. DAAD Araştırma Bursu

    Ludwig Maximillan Universitaet-München, Doğum ve Jinekoloji

  • 2011 2000

    Prof.Dr.

    Ankara Üniversitesi, Doğum ve Jinekoloji Ana Bilim Dalı

  • 1992 1987

    Vet. Hek. Asistan Viyana Veteriner Üniversitesi Çiftliğinde Reprodüktif Sürü İdaresi ve Hastalıkları

    Veterinaermedizinizche Universitaet Wien, Geburtshilfe, Gynaekologie, Andrologie

  • 1984 1983

    Asistan Vet Hek Almanya Hessen- Bad-Hersfeld

    Dr. vet. med. Heinze, Klinik, İneklerde Sürü idaresi ve Sağlığı (Herd-Management)

Education & Training

  • Ph.D. 1992

    Doğum , Jinekoloji, Obtetrik, Androloji ve Suni Tohumlama

    Veterinaer Universitaet Wien

  • Master...

    -

    -

  • Bachelor1983

    -

    Veteriner Fakültesi

Honors, Awards and Grants

Research Projects

  • image

    Maturation of canine feto-maternal axis. Role of utero/placental prostaglandins in the induction of parturition

    investigate the effects of the different timepoints of Alizine application on the utero/placental prostaglandin-synthesis, luteal steroidogenesis and luteal as well as uteroplacental hormonal/receptor status

    Background: The focus of our recent studies (Kowalewski et al., 2009, 2010, 2011a,b) was directed towards the cellular- and molecular mechanisms leading to the onset of parturition in the dog. In order to gain some more information about the molecular and endocrine events governing this process experiments were performed using the competitive progesterone receptor blocker - Alizine (Virbac). We observed similar changes in the utero/placental prostaglandins system during normal and Alizine-induced parturition/abortion. Our main findings pointed towards the progesterone-receptor mediated alterations in the feto-maternal communication, between the maternal decidual cells (the only cells in the canine placenta expressing progesterone receptor) and the fetal trophoblast cells, as the main trigger for the prepartal PGF2? output in the dog. But „similar“ does not mean „identical“. From the clinical point of view it is known that the uterine contractions after the application of Alizine seem to be less pronounced than during the normal parturition. This becomes more obvious when Alizine is being applied in the mid- and late- pregnancy, where fetal resorption is not anymore possible and the application of Alizine must result in an abortion. The action of Alizine beyond 45th day of pregnancy is diminished. From the clinical point of view-administration of this compound as monothepeutic at 3rd timester of pregnancy may not induce the foetal expulsion. Therefore, clinicians have developed several protocols comprising e.g. the usage of oxytocin or PGF2? in order to improve the process of parturition. The effects of Alizine on the cessation of the luteal steroidogenic function (= decrease of peripheral progesterone levels) and uterine contractions and finally on the outcome of parturition seem to depend upon the timepoint of Alizine application during the course of pregnancy Goal: The main goal of the ongoing project is: - to investigate the effects of the different timepoints of Alizine application (early-, mid-, late- pregnancy) on the utero/placental prostaglandin-synthesis, luteal steroidogenesis and luteal as well as uteroplacental hormonal/receptor status. Significance of the planned work: With this project we expect to provide clinically active colleagues with new information that could be helpful in optimizing and developing of new treatment protocols. From the scientific (basic sciences) point of view we expect a significant contribution to the understanding of endocrine mechanisms regulating canine reproduction.

  • image

    The downregulated dog and recrudescence of spermatogenesis.

    The aim of the study is to characterise downregulation of germinative and endocrine testicular function following treatment with a 4.7 mg deslorelin implant in dogs and recrudescence after abolition of downregulation by implant removal.

    (1) University of Copenhagen (UCPH), Department of Large Animal Science, Faculty of Health and Science, Copenhagen University, Denmark, with registered office at Copenhagen, registered under number cvr. 29 97 98 12, represented by Mr Hans Henrik Dietz, Department Head (the “Principal Investigator”). (2) University of Ondokuz Mayıs (UOM), Faculty of Veterinary Medicine, Department of Clinical Sciences, 55200, Samsun, Turkey, represented by Prof. Murat Findik (the “Sub-Contractor”). (3) Prof. Selim Aslan (SA), Nera East University, Veterinary Faculty, Obstetrics and Gynecology, Nicosia-TRNC, CYPRUS, will serve as a coordinator of the study – responsible for coordination of the study at and with UOM and communication with Assoc. Prof. Dr. Sandra Goericke-Pesch from UCPH (the “coordinator”) Project description: The downregulated dog and recrudescence of spermatogenesis The aim of the study is to characterise downregulation of germinative and endocrine testicular function following treatment with a 4.7 mg deslorelin implant in dogs and recrudescence after abolition of downregulation by implant removal. Furthermore, full reversibility of all treatment-induced effects should be confirmed by hemi-castration of 4 dogs at the time of downregulation and weekly follow-ups until return to pre-treatment semen parameters followed by removal of the second testis. Experimental design: All dogs will be submitted to a clinical and andrological examination including measurement of testicular size (length, width, height) and assessment of semen quality. Only healthy dogs without andrological deviations and semen parameters within the normal range as defined by Günzel-Apel et al. (1994) Riesenbeck et al. (2001) and Pesch et al. (2007) (see below) will be included. Day of examination and inclusion into study will be defined as day 0. A blood sample will be collected for hormone measurements (testosterone (T), estradiol-17ß (E2), luteinizing hormone (LH), follicle stimulating hormone (FSH) concentrations etc.). The dogs will be randomly assigned to the following two treatment groups: Group 1 (n=5): control; castration after clinical examination and preservation of testicular and epididymal tissue for further examinations according to the protocol below. Group 2 (n=45): treatment with a slow release GnRH-agonist implant (Suprelorin®, 4.7 mg deslorelin) subcutaneously at the paraumbilical region on day 0, blood sampling and andrological examination including measurement of testicular size on days 28, 56 and 84 (= weeks +4, +8, +12), implant removal under local anaesthesia after 5 months (week 0), surgical castration of four to five dogs each at weeks 0, 1, 2, 3, 4, 5, 6, 8, 10. Following implant removal, weekly blood sampling and andrological examination until castration. On the day of castration, blood sampling, testicular measurements before castration and preservation of testicular and epididymal tissue for further examinations (figure 1). Except for four dogs in week 0, both testes will be removed at the time of castrations. In week 0, hemicastration will be performed in four dogs (figure 2). Weekly semen collections until return to normal (before-treatment) semen parameters (week x) should be performed followed by surgical removal of the second testis (week x+1) and preservation of testicular and epididymal tissue for further examinations.

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http://onlinelibrary.wiley.com/doi/10.1111/j.1439-0531.2006.00838.x/full

General Publication Matrix Metalloproteinase (MMP)-2 and MMP-9 Activity in the Canine Uterus Before and During Placentation, 2016

Abstract


Özet

http://www.sciencedirect.com/science/article/pii/S0378432008005010

General Publication Time related changes in luteal prostaglandin synthesis and steroidogenic capacity during pregnancy, normal and antiprogestin induced luteolysis in the bitch, 2016

Abstract


Özet

http://www.reproduction-online.org/content/139/3/655.short

General Publication Canine placenta: a source of prepartal prostaglandins during normal and antiprogestin-induced parturition, 2016

Abstract


Özet

http://europepmc.org/abstract/med/10887668

General Publication Use of exfoliative cytology for diagnosis of transmissible venereal tumour and controlling the recovery period in the bitch., 2016

Abstract


Özet

http://www.sciencedirect.com/science/article/pii/S0378432010003805

General Publication Evaluation of genes involved in prostaglandin action in equine endometrium during estrous cycle and early pregnancy, 2016

Abstract


Özet

http://rbej.biomedcentral.com/articles/10.1186/1477-7827-9-109

General Publication Luteal and placental function in the bitch: spatio-temporal changes in prolactin receptor (PRLr) expression at dioestrus, pregnancy and normal and induced parturition, 2016

Abstract


Özet

http://onlinelibrary.wiley.com/doi/10.1111/j.1439-0531.2007.00966.x/full

General Publication Expression of Genes in the Canine Pre-implantation Uterus and Embryo: Implications for an Active Role of the Embryo Before and During Invasion, 2016

Abstract


Özet

http://www.sciencedirect.com/science/article/pii/S0093691X10005583

General Publication Expression and functional implications of Peroxisome Proliferator—Activated Receptor Gamma (PPAR?) in canine reproductive tissues during normal pregnancy and parturition and at antiprogestin induced abortion, 2016

Abstract


Özet

http://eski.teb.org.tr/akademi/journal/?p=content&vol=5&no=1

General Publication Spectrophotometric determination of amoxicillin in pharmaceutical formulations, 2016

Abstract


Özet

http://www.sciencedirect.com/science/article/pii/S0093691X07003834

General Publication Repeated induction of abortion in bitches and the effect on plasma concentrations of relaxin, progesterone and estradiol-17ß, 2016

Abstract


Özet

http://www.sciencedirect.com/science/article/pii/S0093691X03003510

General Publication Induction of abortion in queens by administration of cabergoline (Galastop™) solely or in combination with the PGF2? analogue Alfaprostol (Gabbrostim™), 2016

Abstract


Özet

http://www.sciencedirect.com/science/article/pii/S0378432011000583

General Publication Rating of putative housekeeping genes for quantitative gene expression analysis in cyclic and early pregnant equine endometrium, 2016

Abstract


Özet

http://journals.tubitak.gov.tr/veterinary/abstract.htm?id=3118

General Publication The use of laboratory findings in the diagnosis of CEH-pyometra complex in the bitch, 2016

Abstract


Özet

http://onlinelibrary.wiley.com/doi/10.1111/j.1439-0531.2009.01443.x/full

General Publication Cytokines, Growth Factors and Prostaglandin Synthesis in the Uterus of Pregnant and Non-pregnant Bitches: The Features of Placental Sites, 2016

Abstract


Özet

http://scholar.google.com/scholar?cluster=18138338297289057260&hl=en&oi=scholarr

General Publication FRUHGRAVIDITAT UND EMBRYONALE BZW. FRUHFETALE MORTALITAT BEI DER KUH: GELBKORPERDYNAMIK, PROGESTERON-, VITAMIN-E-, VITAMIN-B12-, BETA-CAROTIN-UND F OLSAUREKONZENTRATIONEN IM PERIPHEREN BLUT, 2016

Abstract


Özet

http://onlinelibrary.wiley.com/doi/10.1111/j.1439-0531.2012.02019.x/full

General Publication Vascular Endothelial (VEGF) and Epithelial Growth Factor (EGF) as Well as Platelet-Activating Factor (PAF) and Receptors are Expressed in the Early Pregnant Canine Uterus, 2016

Abstract


Özet

http://scholar.google.com/scholar?cluster=10117852828477023464&hl=en&oi=scholarr

General Publication Fatty acid analysis of some Turkish apricot seed oils by GC and GC–MS techniques, 2016

Abstract


Özet

http://scholar.google.com/scholar?cluster=7800005962841184497&hl=en&oi=scholarr

General Publication Gebelik ve siklus dönemlerinin belirlenmesi amacıyla ratlarda vajinal sitolojinin kullanılması, 2016

Abstract


Özet

http://www.sciencedirect.com/science/article/pii/S0093691X13001258

General Publication Expression of enzymes and receptors of leukotriene pathway genes in equine endometrium during the estrous cycle and early pregnancy, 2016

Abstract


Özet

http://scholar.google.com/scholar?cluster=6693292057238731412&hl=en&oi=scholarr

General Publication Expression of genes involved in the embryo–maternal interaction in the early-pregnant canine uterus, 2016

Abstract


Özet

https://www.researchgate.net/profile/S_Aslan/publication/242716854_neklerde_ge_postpartum_dnemde_PRID_ve_CIDR-B_ile_PGF2a_(liren)_kombinasyonunun_fertilite_parametrelerine_etkisi/links/0f3175394db9577373000000.pdf

General Publication İneklerde geç postpartum dönemde PRID ve CIDR-B ile PGF2a (İliren@) kombinasyonunun fertilite parametrelerine etkisi, 2016

Abstract


Özet

http://scholar.google.com/scholar?cluster=9451233706504405351&hl=en&oi=scholarr

General Publication Systematic Study of Essential Oils of Eucalyptus species Grown in Turkey, 2016

Abstract


Özet

http://onlinelibrary.wiley.com/doi/10.1111/j.1439-0531.2010.01741.x/full

General Publication Effects of induction of ovulation with GnRH or hCG on follicular and luteal blood flow in Holstein–Friesian heifers, 2016

Abstract


Özet

http://www.sciencedirect.com/science/article/pii/S0093691X0800277X

General Publication Induction of abortion with aglepristone significantly changed the expression of progesterone and estrogen receptors in canine endometrial stromal cells, 2016

Abstract


Özet

http://scholar.google.com/scholar?cluster=18401911828487294596&hl=en&oi=scholarr

General Publication Verbesserung der postpartalen Fertilitat von Kuhen durch Pulsatilla miniplex® Improvement of postpartal fertility of cows by Pulsatilla miniplex®, 2016

Abstract


Özet

http://www.revmedvet.com/2010/RMV161_212_218.pdf

General Publication Cytological Evaluation of canine mammary tumours with fine needle aspiration biopsy, 2016

Abstract


Özet

http://onlinelibrary.wiley.com/doi/10.1111/j.1439-0531.2004.00552.x/full

General Publication The Activity of Matrix Metalloproteinase-2 and-9 in Serum of Pregnant and Non-Pregnant Bitches, 2016

Abstract


Özet

http://www.sciencedirect.com/science/article/pii/S0093691X11000422

General Publication The intravaginal application of misoprostol improves induction of abortion with aglepristone, 2016

Abstract


Özet

http://europepmc.org/abstract/med/10916937

General Publication [Comparison of various examination methods used in ovarian diagnostics in cattle], 2016

Abstract


Özet

http://www.academicjournals.org/journal/AJMR/article-abstract/DE3779815500

General Publication An inquiry of knowledge, attitudes and practices against pandemic H1N1 influenza among Turkish health care workers: Experience of a single center in Southeast of Turkey, 2016

Abstract


Özet

http://onlinelibrary.wiley.com/doi/10.1111/j.1439-0531.2009.01390.x/full

General Publication Uterine progesterone receptor and leukaemia inhibitory factor mRNA expression in canine pregnancy, 2016

Abstract


Özet

http://scholar.google.com/scholar?cluster=16965389763342605234&hl=en&oi=scholarr

General Publication Saanen ırkı keçilerde erken gebeliğin B-mode real time ultrasonografi ile tanısı, 2016

Abstract


Özet

https://www.researchgate.net/profile/E_Kurar/publication/265885790_Expression_of_Epidermal_Growth_Factor_(EGF)_and_Heparin-Binding_EGF_(HB-EGF)_mRNA_in_Mare_Endometrium_1/links/550179b70cf231de0769fd15.pdf

General Publication Expression of epidermal growth factor (EGF) and heparin-binding EGF (HB-EGF) mRNA in mare endometrium, 2016

Abstract


Özet

https://www.researchgate.net/profile/Mustafa_Kaymaz/publication/238787032_EINSATZ_DER_PAPANICOLAOAU-F_RBEMETHODE_ZUR_VAGINALZYTOLOGISCHEN_UNTERSUCHUNG_BEl_DER_HNDIN/links/00463528f08df49ae3000000.pdf

General Publication Einsatz Der Papanicolaoau-F Rbemethode Zur Vaginalzytologischen Untersuchung Bel Der Hündin, 2016

Abstract


Özet

http://www.sciencedirect.com/science/article/pii/S0093691X14000508

General Publication Clinical evaluation of different applications of misoprostol and aglepristone for induction of abortion in bitches, 2016

Abstract


Özet

http://www.japtr.org/article.asp?issn=0973-1296;year=2010;volume=6;issue=24;spage=305;epage=308;aulast=Ugur

General Publication Variations in fatty acid compositions of the seed oil of Eruca sativa Mill. caused by different sowing periods and nitrogen forms, 2016

Abstract


Özet

http://scholar.google.com/scholar?cluster=14736026618912812825&hl=en&oi=scholarr

General Publication Trächtigkeitsabbruch bei der Hündin durch kombinierte Gabe eines PGF2?-Analogons (Alfaprostol oder Cloprostenol) und des Ergolinderivates Cabergolin, 2016

Abstract


Özet

http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.562.8345&rep=rep1&type=pdf

General Publication Peripheral plasma progesterone levels during pregnancy in the pure breed Anatolian shepherd dogs, 2016

Abstract


Özet

http://www.academia.edu/download/41806139/Clinical_and_Endocrine_Short-Term_Effects_of_GnRH_Analogue.pdf

General Publication Clinical and endocrine short-term effects of GnRH analogue deslorelin in prepubertal bitches: does a “flare-up” occur?, 2016

Abstract


Özet

http://scholar.google.com/scholar?cluster=16061319118880872039&hl=en&oi=scholarr

General Publication Evcil dişi mandalarda üreme özellikleri, 2016

Abstract


Özet

http://europepmc.org/abstract/med/11889842

General Publication [Suitability of sonographic evaluation of ovarian dynamics and uterine involution for prediction of postpartum fertility in the cow], 2016

Abstract


Özet

http://scholar.google.com/scholar?cluster=7416417090387622166&hl=en&oi=scholarr

General Publication Untersuchungen über die Ovarzyste beim Rind–Entstehung, Therapieerfolge, 2016

Abstract


Özet

http://onlinelibrary.wiley.com/doi/10.1111/j.1439-0531.2010.01619.x/full

General Publication Expression and activity of matrix metalloproteinases in the uterus of bitches after spontaneous and induced abortion, 2016

Abstract


Özet

http://journals.tubitak.gov.tr/veterinary/abstract.htm?id=2773

General Publication The use of proligestone, megestrol acetate and GnRH on queens with the aim of hormonal contraception, 2016

Abstract


Özet

http://onlinelibrary.wiley.com/doi/10.1111/rda.12330/full

General Publication Suppression of Fertility in Pre-pubertal Dogs and Cats, 2016

Abstract


Özet

http://europepmc.org/abstract/med/17009810

General Publication [Plasma concentrations of folic acid, vitamin B12 and progesterone of cyclic bitches, bitches during pregnancy and induced abortion and bitches with pyometra], 2016

Abstract


Özet

http://www.sciencedirect.com/science/article/pii/S0378432014000815

General Publication The effects of aglepristone alone and in combination with cloprostenol on hormonal values during termination of mid-term pregnancy in bitches, 2016

Abstract


Özet

http://onlinelibrary.wiley.com/doi/10.1111/j.1439-0531.2009.01444.x/full

General Publication Expression of MHC-I and-II in Uterine Tissue from Early Pregnant Bitches, 2016

Abstract


Özet

http://www.sciencedirect.com/science/article/pii/S0093691X14006918

General Publication Clinical use of deslorelin implants for the long-term contraception in prepubertal bitches: Effects on epiphyseal closure, body development, and time to puberty, 2016

Abstract


Özet

http://scholar.google.com/scholar?cluster=15350291029677290130&hl=en&oi=scholarr

General Publication Eignung der sonographischen Beurteilung von Ovardynamik und Uterusinvolution zur Fertilitäts-prognose im Puerperium des Rindes, 2016

Abstract


Özet

https://www.researchgate.net/profile/Mehmet_Atli/publication/240617232_Anostrus_semptomu_gosteren_ineklerde_PRID_uygulamalarinin_cesitli_fertilite_parametrelerine_etkisi/links/0c960531dacc9e9030000000.pdf

General Publication Anöstrüs semptomu gösteren ineklerde PRID uygulamalarının çeşitli fertilite parametrelerine etkisi, 2016

Abstract


Özet

https://www.thieme-connect.com/products/ejournals/html/10.1055/s-0032-1324800

General Publication Quantitative software analysis of ultrasonographic textures in experimental testicular torsion, 2016

Abstract


Özet

http://europepmc.org/abstract/med/2245771

General Publication [Ovarian cysts in cattle--etiology, therapy success, fertility], 2016

Abstract


Özet

https://www.researchgate.net/profile/Ibrahim_Kuecuekaslan/publication/51991367_Effect_of_subsequent_two_short-term_short-term_and_long-term_progestagen_treatments_on_fertility_of_Awassi_ewes_out_of_the_breeding_season/links/0912f509b60d517d02000000.pdf

General Publication Effect of subsequent two short-term, short-term, and long-term progestagen treatments on fertility of Awassi ewes out of the breeding season, 2016

Abstract


Özet

http://europepmc.org/abstract/med/20496831

General Publication Intravaginal application of misoprostol improves pregnancy termination with cabergoline and alfaprostol in dogs., 2016

Abstract


Özet

http://scholar.google.com/scholar?cluster=3450611718062506693&hl=en&oi=scholarr

General Publication Ankara keçilerinde gebeliğin 92-97. günlerinde elde edilen ultrasonografik bulgular, 2016

Abstract


Özet

http://scholar.google.com/scholar?cluster=5927134969137273572&hl=en&oi=scholarr

General Publication Wirksamkeit der intrauterinen Behandlung von puerperalen und post-puerperalen Endometritiden mit Eucacomp® bzw. Lotagen® beim Rind., 2016

Abstract


Özet

http://scholar.google.com/scholar?cluster=14066643219282752277&hl=en&oi=scholarr

General Publication Termination of unwanted pregnancies in the bitch by combined application of a PCF2 alpha-analogon (alfaprostol or cloprostenol) and dopamine agonist cabergoline, 2016

Abstract


Özet

http://dergiler.ankara.edu.tr/dergiler/11/1529/16792.pdf

General Publication 3 Tesla Magnetic resonance imaging and multiplanar reconstruction of the brain and its associated structures in pig, 2016

Abstract


Özet

https://www.researchgate.net/profile/Ali_Agaoglu/publication/233801268_Expression_of_platelet_activating_factors_and_its_receptor_in_cat_uterus_during_early_pregnancy/links/004635334124d7268d000000.pdf

General Publication Expression of platelet activating factors and its receptor in cat uterus during early pregnancy, 2016

Abstract


Özet

http://journals.tubitak.gov.tr/veterinary/abstract.htm?id=10625

General Publication Treatment of hypersexuality and benign prostatic hypertrophy with delmadinone acetate in intact male dogs, 2016

Abstract


Özet

http://synapse.koreamed.org/DOIx.php?id=10.4142/jvs.2015.16.2.213

General Publication Tarantula cubensis extract alters the degree of apoptosis and mitosis in canine mammary adenocarcinomas, 2016

Abstract


Özet

http://onlinelibrary.wiley.com/doi/10.1111/j.1439-0531.2006.00636.x/full

General Publication A Screening for the Occurrence of Autoreactive Antibodies in Sera of Pregnant and Non-pregnant Bitches, 2016

Abstract


Özet

http://www.sciencedirect.com/science/article/pii/S092144881300103X

General Publication The effectiveness of supplemental administration of progesterone with GnRH, hCG and PGF 2? on the fertility of Tuj sheep during the non-breeding season, 2016

Abstract


Özet

http://onlinelibrary.wiley.com/doi/10.1111/rda.12063/full

General Publication Is apoptosis a regulatory mechanism during early canine pregnancy?, 2016

Abstract


Özet

http://journals.tubitak.gov.tr/veterinary/abstract.htm?id=6359

General Publication The Relationship Between the Stages of the Sexual Cycle, the Pregnancy and Postpartum Periods and Vaginal Flora in Kangal Breed Bitches, 2016

Abstract


Özet

https://www.researchgate.net/profile/Duygu_Kaya/publication/234062306_Effectiveness_of_Thuja_occidentalis_and_Urtica_urens_inpseudopregnant_bitches/links/0fcfd50ec0c4123e0a000000.pdf

General Publication Effectiveness of Thuja occidentalis and Urtica urens in pseudopregnant bitches, 2016

Abstract


Özet

https://www.researchgate.net/profile/Murat_FINDIK/publication/230792221_The_effectiveness_of_combined_preventive_treatment_with_Ceftiofur_Oxytocin_and_PGF2on_fertility_parameters_in_cows/links/02bfe50cb819bdc004000000.pdf

General Publication The effectiveness of combined preventive treatment with ceftiofur, oxytocin and PGF2? on fertility parameters in cows, 2016

Abstract


Özet

http://scholar.google.com/scholar?cluster=3544107309474163268&hl=en&oi=scholarr

General Publication ABORTEINLEITUNG BEI DER HUNDIN MIT CABERGOLIN (GALASTOP), 2016

Abstract


Özet

http://www.academia.edu/download/35604515/1814.pdf

General Publication Effectiveness of different pharmacological approaches on post-ovariohysterectomy urinary incontinence in the bitch, 2016

Abstract


Özet

http://vetdergi.kafkas.edu.tr/extdocs/2012_6/1035-1041.pdf

General Publication The change in luteal blood flow and luteal size after beta carotene and Gnrh injections in early pregnant dairy cows, 2016

Abstract


Özet

http://veteriner.org.tr/files/dergi/cilt78sayi1/b39-42.pdf

General Publication Homeopati ve veteriner hekimliğinde kullanımı, 2016

Abstract


Özet

http://tpg.schattauer.de/en/contents/archive/manuscript/23708/download.html

General Publication Evaluation of endometrial echotexture and cervical cytology in cows during and after treatment of endometritis, 2016

Abstract


Özet

https://journals.tubitak.gov.tr/veterinary/abstract.htm?id=1287

General Publication Pregnancy diagnosis by using PMSG-Latex Test in mares, 2016

Abstract


Özet

http://vetdergi.kafkas.edu.tr/extdocs/2015_6/877-883.pdf

General Publication Investigation of the Effects of Acupuncture Stimulation on the Size and Blood Flow of Corpus Luteum and Progesterone Levels in Dairy Cows, 2016

Abstract


Özet

http://scholar.google.com/scholar?cluster=13836671296925612401&hl=en&oi=scholarr

General Publication Efficacy of intrauterine administration of Eucacomp® and Lotagen® in cases of puerperal and postpuerperal endometritis in dairy cattle, 2016

Abstract


Özet

http://www.sciencedirect.com/science/article/pii/S0093691X15003933

General Publication GnRH and its receptor (GnRH-R) are expressed in the canine placenta and uterus, 2016

Abstract


Özet

http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.513.6623&rep=rep1&type=pdf

General Publication The efficacy of intramammary, systemic and combined antibiotics administered during dry off in cows with subclinical mastitis, 2016

Abstract


Özet

http://scholar.google.com/scholar?cluster=3918215739849880306&hl=en&oi=scholarr

General Publication Expression of alpha subunits of hypoxia inducible factor (HIF) mRNA are regulated during the estrous cycle and early pregnancy in mare endometrium, 2016

Abstract


Özet

http://scholar.google.com/scholar?cluster=15530749908651045708&hl=en&oi=scholarr

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General Publication Investigation of combustion resistance of wood-based panels treated with different chemicals., 2016

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General Publication Uterine involution, follicle development and concentrations of plasma progesterone, 20?-OH-progesterone and total estrogen levels during the postpartum period in anatolian donkeys, 2016

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General Publication The expression of cytokines, enzymes and receptors in uterine tissue from pregnant and non-pregnant bitches, and the canine embryo, 2016

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General Publication The effect of beta-carotene in combination with PGF2 alpha+ GnRH treatment on ovarian cysts in cows, 2016

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General Publication Immunohistochemical Findings of Canine Mammary Adenocarcinomas after therapie with Tarantula Cubensis, 2016

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General Publication Beneficial effects of Beta-carotene injections prior to treatment with PGF (2) alpha on the fertility of postpartum dairy cows, 2016

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Özet

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General Publication İnekte puerperal dönemde düzenli kontrollerin fertilite üzerindeki etkileri, 2016

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General Publication Difli Kedilerde Hormonal Kontrasepsiyon Amac› yla Proligeston, Megestrol Asetat ve GnRH Kullan› m›, 2016

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General Publication Expression of hypoxia-inducible factors and vascular endothelial growth factor during pregnancy in the feline uterus, 2016

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General Publication A DCT-based multiscale binary descriptor robust to complex brightness changes, 2016

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General Publication In-vitro model of canine decidualization, 2016

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General Publication Effects of different concentrations of monensin on the electrocardiogram and the serum ion balance of the rabbit, 2016

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General Publication Kisspeptin-10 and the G protein-coupled receptor 54 are differentially expressed in the canine pregnant uterus and trophoblast cells, 2016

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General Publication Early pregnancy and embryonic/fetal mortality in the cow-luteal dynamics, progesterone-, vitamin E-, vitamin B-12-, carotene-and folic acid-concentrations in peripheral blood, 2016

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General Publication Gene expression profiles of some cytokines, growth factors, receptors, and enzymes (GM-CSF, IFN?, MMP-2, IGF-II, EGF, TGF-ß, IGF-IIR) during pregnancy in the cat uterus, 2016

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General Publication Effect of deslorelin on testicular function, serum dihydrotestosterone and oestradiol concentrations during and after suppression of sexual activity in tom cats, 2016

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General Publication The effects of Cosynch-56 protocol on pregnancy rates of cows and heifers presynchronized with a single dose of PGF (2 alpha), 2016

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General Publication Acupuncture stimulation causes earlier increase in the size and blood flow of corpus luteum and progesterone levels in dairy cows, 2016

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General Publication A novel study on developing a model-driven visual dictionary, 2016

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General Publication Association of luteal blood flow with follicular size, serum estrogen and progesterone concentrations, and the inducibility of luteolysis by PGF 2? in dairy cows, 2016

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General Publication Evaluation of a subunits of hypoxia inducible factor (HIF) and Vascular Endothelial Growth Factor (VEGF) expressions during pregnancy in domestic cats, 2016

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General Publication The effectiveness of supplemental administration of progesterone with GnRH, hCG and PGF2 on the fertility of Tuj sheep during the non-breeding season, 2016

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Özet

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General Publication The effect of a misapplied progesterone-releasing intravaginal device on fertility in a Holstein-Friesian cow., 2016

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General Publication Expressions of peroxisome proliferator activator receptor (PPAR) genes in equine endometrium, 2016

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General Publication İneklerde Reprodüktif Sürü İdaresi Programı Kapsamında Postpartum Dönemin İzlenmesi ve Fertiliteye Katkısı., 2016

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General Publication Expressions of platelet-activating factors (PAF), PAF receptor (PAF-R) and PAF-acetylhydrolase (PAF-AH) mRNAs during the estrous cycle and early pregnancy in equine endometrium, 2016

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General Publication Embryo-maternal interaction during the process of decidualization in the early pregnant canine uterus, 2016

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General Publication Gene expression profiles of cytokines (GM-CSF, IFN gamma, MMP2), growth factors (IGF-2, EGF, TGF-beta) and IGF2R during pregnancy in cat uterus, 2016

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General Publication AISI 316Ti Paslanmaz Çeliğin Tornalanmasında Kesici Uç Etkisinin Taguchi Yöntemi ile Analizi, 2016

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General Publication Bewertung von Echotexturparametern des Endometriums und zytologischen Zervixbefunden bei Kühen während und nach Behandlung einer Endometritis, 2016

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General Publication Preliminary expression analysis of global microRNA and biogenesis pathway in equine endometrium during the estrous cycle and early pregnancy, 2016

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General Publication The effect of acupuncture application during diestrus periods on the size and blood flow of corpus luteum and hormonal parameters in dairy cows, 2016

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General Publication The effect of corpus luteum and follicle sizes on ovsynch procedure in lactating cows, 2016

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General Publication Oral Communications, 2016

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General Publication The effect of beta-carotene and GnRH administration on luteal size and luteal blood flow after synchronization with prostaglandin F-2 alpha in cows, 2016

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General Publication Expressions of Insulin-Like Growth Factor (IGF)-I,-II and their receptor genes are regulated in mare endometrium during estrous cycle and early pregnancy, 2016

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General Publication Die intravaginale Applikation von Misopristol verbessert den Trächtigkeitsabbruch mit Cabergolin und Alfaprostol bei Hündinnen, 2016

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General Publication Expression of factors involved in decidualization and implantation in canine early pregnant uterus, 2016

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General Publication MHC-I and-II expression in uterine tissues after induced and spontaneous canine abortions, 2016

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General Publication Selection of housekeeping gene for quantitative gene expression in cyclic and early pregnant equine endometrium, 2016

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General Publication Cytological Evaluation Of Canine Mammary Tumours With Fine Needle Aspiration Biopsy Technique, 2016

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General Publication Molecular implications of canine placental endocrine function Introduction, 2016

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General Publication The effectiveness of progesterone support administrations of GnRH, hCG and PGF2 alpha on fertility of Tuj sheep during the non-breeding season, 2016

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General Publication Epidermal growth factor (EGF) and heparin binding-EGF (HB-EGF) mRNA expressions in cyclic and pregnant mare endometrium, 2016

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General Publication Evaluatoin of Vaginal Cytology by Traditional Microscopy Method and BS200Pro Software in Digital Format for Cycle Determination in Bitches, 2016

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General Publication Intravaginal application of the PGE1 analog misoprostol improves induction of abortion in bitches, 2016

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General Publication Leukotriene pathway genes are regulated at mRNA levels in equine endometrium during estrous cycle and early pregnancy, 2016

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General Publication Clinical and endocrinological effects of two different treatments for the induction of abortion in bitches, 2016

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General Publication Expression of Toll-like Receptors (TLRs) Is Regulated by Early Pregnancy in the Mare Endometrium., 2016

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General Publication PLS-DA approach for simultaneous evaluation of genes involved in luteolysis in equine endometrium during estrous cycle and early pregnancy, 2016

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General Publication Evaluation of Genes Involved in Prostaglandin Action in Equine Endometrium During Estrous Cycle and Early Pregnancy., 2016

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General Publication Effect of Repeated Intrauterine and PGF2 alpha Treatments on Reproductive Performance in Cows with Chronic Endometritis, 2016

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General Publication Estrogen Receptor (ER) alpha, ER beta and Progesterone Receptor (PR) Expression in Equine Endometrium during Estrous Cycle and Early Pregnancy, 2016

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General Publication The expression and activity of MMP-2 and MMP-9 in the uterus of pregnant bitches after spontaneous and induced abortion, 2016

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General Publication Evaluation cytologique des tumeurs mammaires chez la chienne après biopsie par aspiration à laiguille fine., 2016

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General Publication Effects of Induction of Ovulation by GnRH or hCG on Follicular and Luteal Blood Flow and Plasma Steroid Levels in Holstein Friesian Cows, 2016

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General Publication Efficiency of postpartum beta-carotene and PGF (2) alpha treatment on fertility parameters in dairy cows, 2016

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General Publication Wirksamkeit von Thuja occidentalis und Urtica urens bei der Scheintrachtigkeit der Hundin, 2016

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General Publication Use of Echo-texture Parameters for the Determination of Different Degree Endometritis in Cows and Evaluation of the Recovery Period after Treatment, 2016

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General Publication Studies on the changes in the blood flow of the Corpus luteum, the follicle and the luteal cysts by means of Colour doppler sonography with cortex, 2016

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General Publication Plasmakonzentrationen von Folsäure, Vitamin B12 und Progesteron während des Sexualzyklus, Gravidität, Abortinduktion und Pyometra bei der Hündin, 2016

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General Publication The effects of Pulsatilla miniplex on haematologic parameters in dairy cows, 2016

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General Publication Comparison of various diagnostic techniques used for examination of ovaries in cows., 2016

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General Publication The expression of MHC I-II and MMP 2 and 9 in uterine tissue of early pregnant bitches, 2016

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General Publication Efficiency of cabergoline in terminating unwanted pregnancies in the bitch, 2016

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General Publication Ultrasonic imaging of follicle and uterus dynamics in the puerperium of the COW, 2016

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General Publication Determination of Pregnancy, Embryonic-Fetal Mortality, Ovarium Functions and Uterus Diameter in Cows by Ultrasonography, 2016

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General Publication Expression of cyclooxygenase 2 (Cox2), prostaglandin F2?-synthase (PGFS) and its receptor (PGFR) in canine placenta at normal and antiprogestin induced parturition, 2016

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General Publication Repeated induction of abortion in bitches and the effect on plasma concentrations of relaxin, progesterone and estradiol-17?, 2016

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General Publication Programm der Postersitzungen-Freitag, 19. Februar 1999-ab 09.30-Postersession IV-Gynagologie 2 (PV/52-66)-Efficiency of cabergoline in terminating unwanted pregnancies in the bitch, 2016

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General Publication The effects of Pulsatilla miniplex (R) administrations on some blood values in dairy cows, 2016

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General Publication The Effectiveness of Progesterone-Releasing Intravaginal Device with Daily GnRH Injections on the Reproductive Parameters of Mares in Diestrus, 2016

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General Publication Gelbkörpergröfie, Progesteron-, Vitamin E-und fi-Carotin-Gehalt bei graviden Kühen, 2016

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General Publication Beneficial effects of Beta-carotene injections prior to treatment with PGF 2a on the fertility of postpartum dairy cows, 2016

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Abstract


Özet

Kedilerde vaginal smear yöntemi ile siklus dönemlerinin saptanması ve ovaryumlar üzerindeki yapılar arasındaki ilişkinin araştırılması

Original Article Cilt/Volume 52• Sayı/Number 1• 2005, Volume *, Issue -, 1900, Pages -

Abstract

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Özet

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Kedilerde vaginal smear yöntemi ile siklus dönemlerinin saptanması ve ovaryumlar üzerindeki yapılar arasındaki ilişkinin araştırılması

Original Article Cilt/Volume 52• Sayı/Number 1• 2005, Volume *, Issue -, 1900, Pages -

Abstract

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Özet

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Ratlarda Reproduktif Sistem

Original Article Journal of Clinical and Analytical Medicine, Volume *, Issue -, 1900, Pages -

Abstract

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Özet

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Kedilerde vaginal smear yöntemi ile siklus dönemlerinin saptanması ve ovaryumlar üzerindeki yapılar arasındaki ilişkinin araştırılması

Original Article Cilt/Volume 52• Sayı/Number 1• 2005, Volume *, Issue -, 1900, Pages -

Abstract

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Özet

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Ratlarda Reproduktif Sistem

Original Article Journal of Clinical and Analytical Medicine, Volume *, Issue -, 1900, Pages -

Abstract

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Özet

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Ratlarda Reproduktif Sistem

Original Article Journal of Clinical and Analytical Medicine, Volume *, Issue -, 1900, Pages -

Abstract

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Özet

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The post partum period in cows with and without retention of membranes and after induced parturatio

Original Article WIENER TIERARZTLICHE MONATSSCHRIFT, Volume *, Issue -, 1989, Pages -

Abstract

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Özet

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THE POST PARTUM PERIOD IN COWS WITH AND WITHOUT RETENTION OF MEMBRANES AND AFTER INDUCED PARTURITION

Original Article WIENER TIERARZTLICHE MONATSSCHRIFT, Volume *, Issue -, 1989, Pages -

Abstract

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Özet

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Untersuchungen über die Ovarzyste beim Rind–Entstehung, Therapieerfolge

Original Article Fruchtbarkeit. Dtsch. tierärztl. Wochenschr, Volume *, Issue -, 1990, Pages -

Abstract

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Özet

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Untersuchungen über die Ovarzyste beim Rind–Entstehung, Therapieerfolge

Original Article Fruchtbarkeit. Dtsch. tierärztl. Wochenschr, Volume *, Issue -, 1990, Pages -

Abstract

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Özet

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[Ovarian cysts in cattle--etiology, therapy success, fertility]

Original Article DTW. Deutsche tierarztliche Wochenschrift, Volume *, Issue -, 1990, Pages -

Abstract

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Özet

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Changes of the bovine corpus luteus size and its progesteron content in the peripheral blood in the time of early pregnancy

Original Article Reproduction in Domestic Animals (Germany), Volume *, Issue -, 1992, Pages -

Abstract

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Özet

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Changes of the bovine corpus luteus size and its progesteron content in the peripheral blood in the time of early pregnancy

Original Article Reproduction in Domestic Animals (Germany), Volume *, Issue -, 1992, Pages -

Abstract

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Özet

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Ankara keçilerinde gebeliğin 92-97. günlerinde elde edilen ultrasonografik bulgular

Original Article AÜ Vet. Fak. Derg, Volume *, Issue -, 1993, Pages -

Abstract

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Özet

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Saanen ırkı keçilerde erken gebeliğin B-mode real time ultrasonografi ile tanısı

Original Article Ankara Üniv Vet Fak Derg, Volume *, Issue -, 1993, Pages -

Abstract

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Özet

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Ankara keçilerinde gebeliğin 92-97. günlerinde elde edilen ultrasonografik bulgular

Original Article AÜ Vet. Fak. Derg, Volume *, Issue -, 1993, Pages -

Abstract

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Özet

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Saanen ırkı keçilerde erken gebeliğin B-mode real time ultrasonografi ile tanısı

Original Article Ankara Üniv Vet Fak Derg, Volume *, Issue -, 1993, Pages -

Abstract

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Özet

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İnekte puerperal dönemde düzenli kontrollerin fertilite üzerindeki etkileri

Original Article Ankara Üniv Vet Fak Derg, Volume *, Issue -, 1995, Pages -

Abstract

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Özet

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Einsatz der Papanicolaou-Färbemethode zur vaginalzytologischen untersuchung bei der hündin

Original Article Ankara Üniv Vet Fak Derg, Volume *, Issue -, 1995, Pages -

Abstract

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Özet

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Einsatz der Papanicolaou-Färbemethode zur vaginalzytologischen untersuchung bei der hündin

Original Article Ankara Üniv Vet Fak Derg, Volume *, Issue -, 1995, Pages -

Abstract

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Özet

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İnekte puerperal dönemde düzenli kontrollerin fertilite üzerindeki etkileri

Original Article Ankara Üniv Vet Fak Derg, Volume *, Issue -, 1995, Pages -

Abstract

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Özet

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Pregnancy diagnosis by using PMSG-Latex Test in mares

Original Article TURKISH JOURNAL OF VETERINARY AND ANIMAL SCIENCES, Volume *, Issue -, 1997, Pages -

Abstract

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Özet

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Pregnancy diagnosis by using PMSG-Latex Test in mares

Original Article TURKISH JOURNAL OF VETERINARY AND ANIMAL SCIENCES, Volume *, Issue -, 1997, Pages -

Abstract

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Özet

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Effects of different concentrations of monensin on the electrocardiogram and the serum ion balance of the rabbit

Original Article Turkish Journal of Veterinary and Animal Sciences, Volume *, Issue -, 1998, Pages -

Abstract

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Özet

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Ultrasonic imaging of follicle and uterus dynamics in the puerperium of the COW

Original Article REPRODUCTION IN DOMESTIC ANIMALS, Volume *, Issue -, 1998, Pages -

Abstract

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Özet

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Early pregnancy and embryonic/fetal mortality in the cow-luteal dynamics, progesterone-, vitamin E-, vitamin B-12-, carotene-and folic acid-concentrations in peripheral blood

Original Article WIENER TIERARZTLICHE MONATSSCHRIFT, Volume *, Issue -, 1998, Pages -

Abstract

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Özet

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FRUHGRAVIDITAT UND EMBRYONALE BZW. FRUHFETALE MORTALITAT BEI DER KUH: GELBKORPERDYNAMIK, PROGESTERON-, VITAMIN-E-, VITAMIN-B12-, BETA-CAROTIN-UND F OLSAUREKONZENTRATIONEN IM PERIPHEREN BLUT

Original Article Wiener tiernrztliche Monatsschrift, Volume *, Issue -, 1998, Pages -

Abstract

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Özet

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FRUHGRAVIDITAT UND EMBRYONALE BZW. FRUHFETALE MORTALITAT BEI DER KUH: GELBKORPERDYNAMIK, PROGESTERON-, VITAMIN-E-, VITAMIN-B12-, BETA-CAROTIN-UND F OLSAUREKONZENTRATIONEN IM PERIPHEREN BLUT

Original Article Wiener tiernrztliche Monatsschrift, Volume *, Issue -, 1998, Pages -

Abstract

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Özet

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Early pregnancy and embryonic/fetal mortality in the cow-luteal dynamics, progesterone-, vitamin E-, vitamin B-12-, carotene-and folic acid-concentrations in peripheral blood

Original Article WIENER TIERARZTLICHE MONATSSCHRIFT, Volume *, Issue -, 1998, Pages -

Abstract

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Özet

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Ultrasonic imaging of follicle and uterus dynamics in the puerperium of the COW

Original Article REPRODUCTION IN DOMESTIC ANIMALS, Volume *, Issue -, 1998, Pages -

Abstract

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Özet

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Determination of Pregnancy, Embryonic-Fetal Mortality, Ovarium Functions and Uterus Diameter in Cows by Ultrasonography

Original Article Turkish Journal of Veterinary and Animal Sciences, Volume *, Issue -, 1999, Pages -

Abstract

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Özet

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Effects of Megestrol Acetate Treatment on Dogs with Prolonged Estrus

Original Article Turkish Journal of Veterinary and Animal Sciences, Volume *, Issue -, 1999, Pages -

Abstract

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Özet

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Determination of Pregnancy, Embryonic-Fetal Mortality, Ovarium Functions and Uterus Diameter in Cows by Ultrasonography

Original Article Turkish Journal of Veterinary and Animal Sciences, Volume *, Issue -, 1999, Pages -

Abstract

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Özet

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ABORTEINLEITUNG BEI DER HUNDIN MIT CABERGOLIN (GALASTOP)

Original Article Tierärztliche Umschau, Volume *, Issue -, 1999, Pages -

Abstract

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Özet

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Programm der Postersitzungen-Freitag, 19. Februar 1999-ab 09.30-Postersession IV-Gynagologie 2 (PV/52-66)-Efficiency of cabergoline in terminating unwanted pregnancies in the bitch

Original Article Reproduction in Domestic Animals, Volume *, Issue -, 1999, Pages -

Abstract

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Özet

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Efficiency of cabergoline in terminating unwanted pregnancies in the bitch

Original Article REPRODUCTION IN DOMESTIC ANIMALS, Volume *, Issue -, 1999, Pages -

Abstract

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Özet

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ABORTEINLEITUNG BEI DER HUNDIN MIT CABERGOLIN (GALASTOP)

Original Article Tierärztliche Umschau, Volume *, Issue -, 1999, Pages -

Abstract

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Özet

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Effects of Megestrol Acetate Treatment on Dogs with Prolonged Estrus

Original Article Turkish Journal of Veterinary and Animal Sciences, Volume *, Issue -, 1999, Pages -

Abstract

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Özet

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The use of laboratory findings in the diagnosis of CEH-pyometra complex in the bitch

Original Article Turkish Journal of Veterinary and Animal Sciences, Volume *, Issue -, 1999, Pages -

Abstract

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Özet

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Programm der Postersitzungen-Freitag, 19. Februar 1999-ab 09.30-Postersession IV-Gynagologie 2 (PV/52-66)-Efficiency of cabergoline in terminating unwanted pregnancies in the bitch

Original Article Reproduction in Domestic Animals, Volume *, Issue -, 1999, Pages -

Abstract

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Özet

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The use of proligestone, megestrol acetate and GnRH on queens with the aim of hormonal contraception

Original Article Turkish Journal of Veterinary and Animal Sciences, Volume *, Issue -, 1999, Pages -

Abstract

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Özet

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Efficiency of cabergoline in terminating unwanted pregnancies in the bitch

Original Article REPRODUCTION IN DOMESTIC ANIMALS, Volume *, Issue -, 1999, Pages -

Abstract

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Özet

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The use of laboratory findings in the diagnosis of CEH-pyometra complex in the bitch

Original Article Turkish Journal of Veterinary and Animal Sciences, Volume *, Issue -, 1999, Pages -

Abstract

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Özet

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The use of proligestone, megestrol acetate and GnRH on queens with the aim of hormonal contraception

Original Article Turkish Journal of Veterinary and Animal Sciences, Volume *, Issue -, 1999, Pages -

Abstract

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Özet

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Use of exfoliative cytology for diagnosis of transmissible venereal tumour and controlling the recovery period in the bitch.

Original Article DTW. Deutsche tierarztliche Wochenschrift, Volume *, Issue -, 2000, Pages -

Abstract

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Özet

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Original Article -, Volume -, Issue -, 2000, Pages -

Abstract

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Özet

Yayınlar 2017 Morphological, histological and molecular investigations on canine uterine tissue after ovariectomy S Schäfer-Somi, K Deichsel, H Beceriklisoy, D Korkmaz, I Walter, S Aslan Theriogenology 102, 80-86 2017 Functional implications of the utero-placental relaxin (RLN) system in the dog throughout pregnancy and at term M Nowak, A Gram, A Boos, S Aslan, SS Ay, F Önyay, MP Kowalewski Reproduction 154 (4), 415-431 2017 Expression of GnRH receptor in the canine corpus luteum, and luteal function following deslorelin acetate-induced puberty delay D Kaya, A Gram, MP Kowalewski, S Schäfer-Somi, M Kuru, A Boos, ... Reproduction in Domestic Animals 2017 Early pregnancy diagnosis in dairy cows by ultrasound and determination of bovine-pregnancy-associated glycoproteins, bovine pregnancy specific protein B and progesterone O Ergene, I Darbaz, S Sayiner, S Aslan REPRODUCTION IN DOMESTIC ANIMALS 52, 83-83 2017 Uterine responses to early pre-attachment embryos in the domestic dog and comparisons with other domestic animal species FR Graubner, A Gram, E Kautz, S Bauersachs, S Aslan, AR Agaoglu, ... Biology of Reproduction 97 (2), 197-216 2017 Kisspeptin-10 and the G protein-coupled receptor 54 are differentially expressed in the canine pregnant uterus and trophoblast cells S Schäfer-Somi, SS Ay, D Kaya, M Sözmen, HB Beceriklisoy, AR Ağaoğlu, ... Reproduction in Domestic Animals 52 (S2), 123-129 1 2017 Effect of deslorelin on testicular function, serum dihydrotestosterone and oestradiol concentrations during and after suppression of sexual activity in tom cats N Gültiken, S Aslan, SS Ay, MY Gülbahar, J Thuróczy, E Koldaş, D Kaya, ... Journal of feline medicine and surgery 19 (2), 123-131 1 2017 The Assessment of Diagnostic and Ultrasonographic Findings in a Bitch with True Vaginal Prolapse I Darbaz, O Ergene, E Canooglu, C Gultekin, S Aslan Kafkas Üniversitesi Veteriner Fakültesi Dergisi 23 (5), 843-846 2017 Koyun ve Keçilerde Metabolik Problemler ve Reprodüksiyona Etkileri S ASLAN, İ DARBAZ, O ERGENE Turkiye Klinikleri Journal of Veterinary Sciences-Obstetrics and Gynecology … 2017 Ovarian Tumour in a Bitch: Diagnosis, Surgery and Recovery I Darbaz, O Ergene, G Sonmez, S Aslan Kafkas Üniversitesi Veteriner Fakültesi Dergisi 23 (5), 839-842 2017 Pregnancy Markers in Serum of Bitches S Schäfer-SOMI, S ASLAN Turkiye Klinikleri Journal of Veterinary Sciences-Obstetrics and Gynecology … 2017 Association of luteal blood flow with follicular size, serum estrogen and progesterone concentrations, and the inducibility of luteolysis by PGF 2? in dairy cows S Kaya, C Kaçar, B Polat, A Çolak, D Kaya, İS Gürcan, H Bollwein, ... Theriogenology 87, 167-172 2 2017

Comparison of various diagnostic techniques used for examination of ovaries in cows.

Original Article Deutsche Tierärztliche Wochenschrift, Volume *, Issue -, 2000, Pages -

Abstract

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Özet

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Use of exfoliative cytology for diagnosis of transmissible venereal tumour and controlling the recovery period in the bitch.

Original Article DTW. Deutsche tierarztliche Wochenschrift, Volume 107, Issue 5, 2000, Pages 175-180

Abstract

Transmissible venereal tumour (TVT) is a rare vaginal tumour that can be treated surgically or cryosurgically as well as by radiotherapy or chemotherapy. Vincristine has been found to be very effective for treating TVT. Since vaginal secretion or discharge may contain neoplastic cells, the cytological identification of TVT cells is possible. The present study was carried out in 12 bitches. Vaginal smears were obtained with cotton swab from the anterior vagina and TVT suspected structures. The smears were stained according to Papanicolaou and assessed by light microscopy. Additionally the general condition of the patients was evaluated by haematological and radiographic examinations. In bitches with TVT vincristine sulphate was administered intravenously at weekly intervals. The total treatment period was three to six weeks until no atypical cells were found in the smear. This was the case after an average of 3.2 +/- 1.3 applications. Tumour masses became smaller and by this non-visible from the rima vulva after 4.2 +/- 0.7 applications. During the treatment, two of the 12 bitches (16.7%) suffered from vomiting and diarrhoea while three (25%) showed neutropenia. Twelve months after completion of treatment, the bitches were examined again and vaginal smears were taken in order to control the recovery process or a possible recurrence of TVT. No atypical cells were found in any vaginal smear. By this exfoliative cytology has proved to be a safe and easy method for TVT diagnosis and for observing the recovery process.


Özet

english

[Comparison of various examination methods used in ovarian diagnostics in cattle]

Original Article DTW. Deutsche tierarztliche Wochenschrift, Volume *, Issue -, 2000, Pages -

Abstract

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Özet

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Verbesserung der postpartalen Fertilitat von Kuhen durch Pulsatilla miniplex® Improvement of postpartal fertility of cows by Pulsatilla miniplex®

Original Article WIENER TIERARZTLICHE MONATSSCHRIFT, Volume *, Issue -, 2000, Pages -

Abstract

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Özet

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Verbesserung der postpartalen Fertilitat von Kuhen durch Pulsatilla miniplex® Improvement of postpartal fertility of cows by Pulsatilla miniplex®

Original Article WIENER TIERARZTLICHE MONATSSCHRIFT, Volume *, Issue -, 2000, Pages -

Abstract

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Özet

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Comparison of various diagnostic techniques used for examination of ovaries in cows.

Original Article Deutsche Tierärztliche Wochenschrift, Volume *, Issue -, 2000, Pages -

Abstract

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Özet

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[Comparison of various examination methods used in ovarian diagnostics in cattle]

Original Article DTW. Deutsche tierarztliche Wochenschrift, Volume *, Issue -, 2000, Pages -

Abstract

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Özet

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Termination of unwanted pregnancies in the bitch by combined application of a PCF2 alpha-analogon (alfaprostol or cloprostenol) and dopamine agonist cabergoline

Original Article Kleintierpraxis, Volume *, Issue -, 2001, Pages -

Abstract

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Özet

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Trächtigkeitsabbruch bei der Hündin durch kombinierte Gabe eines PGF2a-Analogons (Alfaprostol oder Cloprostenol) und des Ergolinderivates Cabergolin

Original Article Kleintierpraxis, Volume *, Issue -, 2001, Pages -

Abstract

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Özet

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Trächtigkeitsabbruch bei der Hündin durch kombinierte Gabe eines PGF2a-Analogons (Alfaprostol oder Cloprostenol) und des Ergolinderivates Cabergolin

Original Article Kleintierpraxis, Volume *, Issue -, 2001, Pages -

Abstract

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Özet

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Termination of unwanted pregnancies in the bitch by combined application of a PCF2 alpha-analogon (alfaprostol or cloprostenol) and dopamine agonist cabergoline

Original Article Kleintierpraxis, Volume *, Issue -, 2001, Pages -

Abstract

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Özet

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[Suitability of sonographic evaluation of ovarian dynamics and uterine involution for prediction of postpartum fertility in the cow]

Original Article DTW. Deutsche tierarztliche Wochenschrift, Volume *, Issue -, 2002, Pages -

Abstract

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Özet

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Eignung der sonographischen Beurteilung von Ovardynamik und Uterusinvolution zur Fertilitäts-prognose im Puerperium des Rindes

Original Article DTW. Deutsche tierärztliche Wochenschrift, Volume *, Issue -, 2002, Pages -

Abstract

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Özet

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Eignung der sonographischen Beurteilung von Ovardynamik und Uterusinvolution zur Fertilitäts-prognose im Puerperium des Rindes

Original Article DTW. Deutsche tierärztliche Wochenschrift, Volume *, Issue -, 2002, Pages -

Abstract

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Özet

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[Suitability of sonographic evaluation of ovarian dynamics and uterine involution for prediction of postpartum fertility in the cow]

Original Article DTW. Deutsche tierarztliche Wochenschrift, Volume *, Issue -, 2002, Pages -

Abstract

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Özet

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The Relationship Between the Stages of the Sexual Cycle, the Pregnancy and Postpartum Periods and Vaginal Flora in Kangal Breed Bitches

Original Article Turkish Journal of Veterinary and Animal Sciences, Volume *, Issue -, 2003, Pages -

Abstract

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Özet

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Kangal Irk› Difli Köpeklerde Seksüel Siklus Evreleri, Gebelik ve Postpartum Dönem ile Vaginal Flora Aras› ndaki‹ liflki

Original Article Turk J Vet Anim Sci, Volume *, Issue -, 2003, Pages -

Abstract

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Özet

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The Relationship Between the Stages of the Sexual Cycle, the Pregnancy and Postpartum Periods and Vaginal Flora in Kangal Breed Bitches

Original Article Turkish Journal of Veterinary and Animal Sciences, Volume *, Issue -, 2003, Pages -

Abstract

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Özet

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Kangal Irk› Difli Köpeklerde Seksüel Siklus Evreleri, Gebelik ve Postpartum Dönem ile Vaginal Flora Aras› ndaki‹ liflki

Original Article Turk J Vet Anim Sci, Volume *, Issue -, 2003, Pages -

Abstract

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Özet

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Die Frühgravidität: Immunologische Regelmechanismen während der Invasionsphase

Original Article Nova acta Leopoldina, Volume *, Issue -, 2004, Pages -

Abstract

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Özet

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İneklerde geç postpartum dönemde PRID ve CIDR-B ile PGF2? (İliren®) kombinasyonunun fertilite parametrelerine etkisi

Original Article Ankara Üniv Vet Fak Derg, Volume *, Issue -, 2004, Pages -

Abstract

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Özet

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Akkaraman ırkı koyunlarda ve Ankara keçilerinde servikal mukus kaynatma testi ile gebelik tanısı

Original Article AÜ Vet. Fak. Derg, Volume *, Issue -, 2004, Pages -

Abstract

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Özet

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Induction of abortion in queens by administration of cabergoline (Galastop™) solely or in combination with the PGF2? analogue Alfaprostol (Gabbrostim™)

Original Article Theriogenology, Volume *, Issue -, 2004, Pages -

Abstract

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Özet

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Induction of abortion in queens by administration of cabergoline (Galastop™) solely or in combination with the PGF2? analogue Alfaprostol (Gabbrostim™)

Original Article Theriogenology, Volume 61, Issue 7-8, 2004, Pages 1471-1475

Abstract

The efficacy of cabergoline solely or combined with a PGF2alpha analogue in inducing abortion at different stages of pregnancy was investigated in 18 queens. The queens were assigned to two treatments: Group I ( n=10 )-cabergoline (15 microg/kg; daily, orally) and Group II ( n=8 )-cabergoline (15 microg/kg; daily, orally) combined with alfaprostol (10 microg/kg; every other day, subcutaneously). Each group was divided into two subgroups according to the duration of pregnancy when treatments started: Group IA ( n=8 ) included queens from Days 34 to 42 after mating. Group IB cats ( n=2 ) started treatments on Day 45 post-mating. Similarly, the combination of cabergoline and PGF2alpha analogue was first given to Group IIA ( n=6 ) from Days 25 to 40 of pregnancy and to Group IIB ( n=2 ) on Days 45 and 47, respectively. Termination of pregnancies was successful in all cats of Group IA, while treatments failed in both cats of Group IB, even though seven and eight treatments, respectively, were given. Mean (+/-S.D.) plasma progesterone concentrations before the start of treatments were 85.0+/-12.3 nmol/l and decreased within 3 days to 8 nmol/l and subsequently to basal values, when the queens aborted (Group IIA, n=6 ) or gave birth prematurely (Group IIB, n=2 ). When abortions failed (Group IB, n=2 ), progesterone concentrations remained elevated (16.9 and 9.8 nmol/l). Duration of combined therapy during late pregnancy in Group IIB ( n=2 ) lasted about 10 days. In both cases, premature birth occurred and the kittens died within 16 h after birth. Overall, treatments starting on Days 25-42 of pregnancy (Groups IA and IIA) had abortion rates of 100%. The average duration of treatments was 5.6+/-1.5 days (range, 3-8). Side effects seen were vomiting and occurred in 6 of the 109 (5.5%) treatments. In conclusion, pregnancies were successfully terminated in the second trimester of feline pregnancy by daily application of cabergoline solely or combined with the PGF2alpha analogue alfaprostol (given every other day). Cabergoline alone was ineffective in inducing abortion at later stages of pregnancy.


Özet

Englisch

Investigation of combustion resistance of wood-based panels treated with different chemicals.

Original Article Süleyman Demirel Üniversitesi Orman Fakültesi Dergisi Seri A, Volume *, Issue -, 2004, Pages -

Abstract

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Özet

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İneklerde geç postpartum dönemde PRID ve CIDR-B ile PGF2? (İliren®) kombinasyonunun fertilite parametrelerine etkisi

Original Article Ankara Üniv Vet Fak Derg, Volume *, Issue -, 2004, Pages -

Abstract

-


Özet

-

Die Frühgravidität: Immunologische Regelmechanismen während der Invasionsphase

Original Article Nova acta Leopoldina, Volume *, Issue -, 2004, Pages -

Abstract

-


Özet

-

Investigation of combustion resistance of wood-based panels treated with different chemicals.

Original Article Süleyman Demirel Üniversitesi Orman Fakültesi Dergisi Seri A, Volume *, Issue -, 2004, Pages -

Abstract

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Özet

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Akkaraman ırkı koyunlarda ve Ankara keçilerinde servikal mukus kaynatma testi ile gebelik tanısı

Original Article AÜ Vet. Fak. Derg, Volume *, Issue -, 2004, Pages -

Abstract

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Özet

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The Activity of Matrix Metalloproteinase-2 and-9 in Serum of Pregnant and Non-Pregnant Bitches

Original Article Reproduction in domestic animals, Volume *, Issue -, 2005, Pages -

Abstract

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Özet

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Wirksamkeit der intrauterinen Behandlung von puerperalen und post-puerperalen Endometritiden mit Eucacomp® bzw. Lotagen® beim Rind.

Original Article Prakt Tierarzt, Volume *, Issue -, 2005, Pages -

Abstract

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Özet

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Effectiveness of different pharmacological approaches on post-ovariohysterectomy urinary incontinence in the bitch

Original Article Ankara Üniv VetFak Derg, Volume *, Issue -, 2005, Pages -

Abstract

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Özet

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Anöstrüs semptomu gösteren ineklerde PRID uygulamalarının çeşitli fertilite parametrelerine etkisi

Original Article Ankara Üniv Vet Fak Derg, Volume *, Issue -, 2005, Pages -

Abstract

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Özet

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Efficacy of intrauterine administration of Eucacomp® and Lotagen® in cases of puerperal and postpuerperal endometritis in dairy cattle

Original Article PRAKTISCHE TIERARZT-HANNOVER-, Volume *, Issue -, 2005, Pages -

Abstract

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Özet

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Anöstrüs semptomu gösteren ineklerde PRID uygulamalarının çeşitli fertilite parametrelerine etkisi

Original Article Ankara Üniv Vet Fak Derg, Volume *, Issue -, 2005, Pages -

Abstract

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Özet

-

The Activity of Matrix Metalloproteinase-2 and-9 in Serum of Pregnant and Non-Pregnant Bitches

Original Article Reproduction in domestic animals, Volume *, Issue -, 2005, Pages -

Abstract

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Özet

-

Effectiveness of different pharmacological approaches on post-ovariohysterectomy urinary incontinence in the bitch

Original Article Ankara Üniv VetFak Derg, Volume *, Issue -, 2005, Pages -

Abstract

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Özet

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Anöstrüs semptomu gösteren ineklerde PRID uygulamalarının çeşitli fertilite parametrelerine etkisi

Original Article Ankara Üniv Vet Fak Derg, Volume *, Issue -, 2005, Pages -

Abstract

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Özet

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Efficacy of intrauterine administration of Eucacomp® and Lotagen® in cases of puerperal and postpuerperal endometritis in dairy cattle

Original Article PRAKTISCHE TIERARZT-HANNOVER-, Volume *, Issue -, 2005, Pages -

Abstract

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Özet

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Wirksamkeit der intrauterinen Behandlung von puerperalen und post-puerperalen Endometritiden mit Eucacomp® bzw. Lotagen® beim Rind.

Original Article Prakt Tierarzt, Volume *, Issue -, 2005, Pages -

Abstract

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Özet

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The efficacy of intramammary, systemic and combined antibiotics administered during dry off in cows with subclinical mastitis

Original Article Veterinary Journal of Ankara University (Turkey), Volume *, Issue -, 2006, Pages -

Abstract

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Özet

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Plasmakonzentrationen von Folsäure, Vitamin B12 und Progesteron während des Sexualzyklus, Gravidität, Abortinduktion und Pyometra bei der Hündin

Original Article DTW. Deutsche tierärztliche Wochenschrift, Volume *, Issue -, 2006, Pages -

Abstract

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Özet

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The efficacy of intramammary, systemic and combined antibiotics administered during dry off in cows with subclinical mastitis

Original Article Veterinary Journal of Ankara University (Turkey), Volume *, Issue -, 2006, Pages -

Abstract

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Özet

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Plasmakonzentrationen von Folsäure, Vitamin B12 und Progesteron während des Sexualzyklus, Gravidität, Abortinduktion und Pyometra bei der Hündin

Original Article DTW. Deutsche tierärztliche Wochenschrift, Volume *, Issue -, 2006, Pages -

Abstract

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Özet

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A Screening for the Occurrence of Autoreactive Antibodies in Sera of Pregnant and Non-pregnant Bitches

Original Article Reproduction in Domestic Animals, Volume *, Issue -, 2006, Pages -

Abstract

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Özet

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[Plasma concentrations of folic acid, vitamin B12 and progesterone of cyclic bitches, bitches during pregnancy and induced abortion and bitches with pyometra]

Original Article DTW. Deutsche tierarztliche Wochenschrift, Volume *, Issue -, 2006, Pages -

Abstract

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Özet

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[Plasma concentrations of folic acid, vitamin B12 and progesterone of cyclic bitches, bitches during pregnancy and induced abortion and bitches with pyometra]

Original Article DTW. Deutsche tierarztliche Wochenschrift, Volume *, Issue -, 2006, Pages -

Abstract

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Özet

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A Screening for the Occurrence of Autoreactive Antibodies in Sera of Pregnant and Non-pregnant Bitches

Original Article Reproduction in Domestic Animals, Volume *, Issue -, 2006, Pages -

Abstract

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Özet

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The efficacy of intramammary, systemic and combined antibiotics administered during dry off in cows with subclinical mastitis

Original Article Veterinary Journal of Ankara University (Turkey), Volume *, Issue -, 2006, Pages -

Abstract

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Özet

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Repeated induction of abortion in bitches and the effect on plasma concentrations of relaxin, progesterone and estradiol-17?

Original Article Theriogenology, Volume *, Issue -, 2007, Pages -

Abstract

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Özet

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The effects of Pulsatilla miniplex on haematologic parameters in dairy cows

Original Article Indian veterinary journal, Volume *, Issue -, 2007, Pages -

Abstract

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Özet

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Homeopati ve veteriner hekimliğinde kullanımı

Original Article Vet Hekim Der Derg, Volume *, Issue -, 2007, Pages -

Abstract

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Özet

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Matrix Metalloproteinase (MMP)-2 and MMP-9 Activity in the Canine Uterus Before and During Placentation

Original Article Reproduction in Domestic Animals, Volume 42, Issue 6, 2007, Pages 654-659

Abstract

The aim of the present study was to demonstrate the presence and localization of MMP-2 and -9 by means of RT-PCR and immunohistochemistry (IHC) within the canine uterus from the pre-implantation stage until mid-gestation and to determine MMP-2 and -9 activities by means of zymography. For this purpose, samples of the uterus and salpinx from bitches were obtained after ovariohysterectomy. Pre-implantation stages (5–12 days after mating, n = 11) were determined by verifying embryos after flushing the uterus. Further groups were determined as implantation (15–19 days after mating, n = 9), post-implantation (20–30 days after mating, n = 9) and placental stages (30–45 days after mating, n = 3). A non-pregnant group (17–30 days after mating, n = 4) served as control. MMP-2 and -9 positive cells were detected in all specimens from pregnant and nonpregnant bitches, however, with different distributions. MMP-2 was present in endothelium and smooth muscles of blood vessels and the myometrium of pregnant and nonpregnant bitches, additionally in the surface epithelium of the oviduct. The latter also stained positive for MMP-9. During placentation, MMP-2 was detected mainly in fetal blood vessels and trophoblastic cells. Higher MMP-2 activity was observed in the endometrium and myometrium of all pregnant groups compared with the nonpregnant group (p < 0.05). The pregnant groups did not differ significantly from each other (p > 0.05). MMP-9 was present in blood vessels, smooth muscle cells and epithelia, such as maternal surface epithelial cells, uterine crypts and glands. During placentation, the deep uterine glands and the epithelium of the glandular chambers were immunoreactive to MMP-9. Highest MMP-9 activities were reached in the endometrium of the pre-implantation group (23.2% of total MMP-9) and placental parts (33.3%).


Özet

English

The effects of Pulsatilla miniplex on haematologic parameters in dairy cows

Original Article Indian veterinary journal, Volume *, Issue -, 2007, Pages -

Abstract

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Özet

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Homeopati ve veteriner hekimliğinde kullanımı

Original Article Vet Hekim Der Derg, Volume *, Issue -, 2007, Pages -

Abstract

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Özet

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Expression of cyclooxygenase 2 (Cox2), prostaglandin F2?-synthase (PGFS) and its receptor (PGFR) in canine placenta at normal and antiprogestin induced parturition

Original Article Experimental and Clinical Endocrinology & Diabetes, Volume *, Issue -, 2007, Pages -

Abstract

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Özet

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Expression of cyclooxygenase 2 (Cox2), prostaglandin F2?-synthase (PGFS) and its receptor (PGFR) in canine placenta at normal and antiprogestin induced parturition

Original Article Experimental and Clinical Endocrinology & Diabetes, Volume *, Issue -, 2007, Pages -

Abstract

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Özet

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Repeated induction of abortion in bitches and the effect on plasma concentrations of relaxin, progesterone and estradiol-17ß

Original Article Theriogenology, Volume 68, Issue 6, 2007, Pages 889-895

Abstract

The aim of the present study was to investigate the effects of two medications on two subsequent abortions and plasma hormone concentrations of dogs. For this purpose, two groups of bitches (n = 5 each), received the antiprogesterone aglepristone (Alizine®) at 10 mg/kg body weight on two subsequent days around day 30 after mating. In group II, the antiprolactin cabergoline (Galastop®) was additionally administered po at 5 µg/kg body weight until the start of abortion. The plasma concentrations of relaxin, progesterone (P4) and estradiol-17ß (E2) were measured before, during and after each abortion. During the next cycle after the abortion, the same bitches were mated again and in pregnant animals, induction of abortion was performed as before. During the third cycle, pregnant bitches were allowed to whelp. Termination of first pregnancy occurred significantly earlier after the combined treatment (6.8 versus 10.6 days, p < 0.05). In both groups and during both abortions, relaxin varied between individuals; however, there was a continuous decrease after the abortions and no significant differences between groups (p > 0.05). In one bitch with high relaxin concentrations before treatment (11.6 ng/ml), a cystic endometrial hyperplasia was diagnosed. In the aglepristone only group, P4 concentrations increased significantly after the first application (p < 0.05), then decreased continuously until day 45 after the beginning of abortion. In the combined group, there was a continuous decrease until day 45 (p > 0.05). At this time, P4 concentrations between 0.47 and 84.9 nmol/l were measured in both groups. The level of E2 over time was not influenced by any medication. We therefore note that the two medications mainly influenced plasma concentrations of P4 in different ways, probably due to specific treatment-hormone interactions. However, all measurements fell within the range considered normal.


Özet

English

Matrix Metalloproteinase (MMP)-2 and MMP-9 Activity in the Canine Uterus Before and During Placentation

Original Article Reproduction in domestic animals, Volume *, Issue -, 2007, Pages -

Abstract

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Özet

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Repeated induction of abortion in bitches and the effect on plasma concentrations of relaxin, progesterone and estradiol-17ß

Original Article Theriogenology, Volume *, Issue -, 2007, Pages -

Abstract

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Özet

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Repeated induction of abortion in bitches and the effect on plasma concentrations of relaxin, progesterone and estradiol-17?

Original Article Theriogenology, Volume *, Issue -, 2007, Pages -

Abstract

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Özet

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Wirksamkeit von Thuja occidentalis und Urtica urens bei der Scheintrachtigkeit der Hundin

Original Article Wiener Tieraerztliche Monatsschrift, Volume *, Issue -, 2008, Pages -

Abstract

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Özet

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Expression of Genes in the Canine Pre-implantation Uterus and Embryo: Implications for an Active Role of the Embryo Before and During Invasion

Original Article Reproduction in domestic animals, Volume *, Issue -, 2008, Pages -

Abstract

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Özet

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Induction of abortion with aglepristone significantly changed the expression of progesterone and estrogen receptors in canine endometrial stromal cells

Original Article Theriogenology, Volume *, Issue -, 2008, Pages -

Abstract

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Özet

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Studies on the changes in the blood flow of the Corpus luteum, the follicle and the luteal cysts by means of Colour doppler sonography with cortex

Original Article ANKARA UNIVERSITESI VETERINER FAKULTESI DERGISI, Volume *, Issue -, 2008, Pages -

Abstract

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Özet

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İneklerde follikül, corpus luteum, ovaryum kistleri olgularında renkli doppler ultrasonografi aracılığıyla vaskülarizasyon değişikliklerinin incelenmesi

Original Article Veterinary Journal of Ankara University (Turkey), Volume *, Issue -, 2008, Pages -

Abstract

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Özet

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Studies on the changes in the blood flow of the Corpus luteum, the follicle and the luteal cysts by means of Colour doppler sonography with cortex

Original Article ANKARA UNIVERSITESI VETERINER FAKULTESI DERGISI, Volume *, Issue -, 2008, Pages -

Abstract

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Özet

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Wirksamkeit von Thuja occidentalis und Urtica urens bei der Scheintrachtigkeit der Hundin

Original Article Wiener Tieraerztliche Monatsschrift, Volume *, Issue -, 2008, Pages -

Abstract

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Özet

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Effectiveness of Thuja occidentalis and Urtica urens in pseudopregnant bitches

Original Article Vet Med Aust Wien Tierarztl Mschr, Volume *, Issue -, 2008, Pages -

Abstract

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Özet

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İneklerde follikül, corpus luteum, ovaryum kistleri olgularında renkli doppler ultrasonografi aracılığıyla vaskülarizasyon değişikliklerinin incelenmesi

Original Article Veterinary Journal of Ankara University (Turkey), Volume *, Issue -, 2008, Pages -

Abstract

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Özet

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Induction of abortion with aglepristone significantly changed the expression of progesterone and estrogen receptors in canine endometrial stromal cells

Original Article Theriogenology, Volume *, Issue -, 2008, Pages -

Abstract

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Özet

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Expression of Genes in the Canine Pre-implantation Uterus and Embryo: Implications for an Active Role of the Embryo Before and During Invasion

Original Article Reproduction in domestic animals, Volume *, Issue -, 2008, Pages -

Abstract

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Özet

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Effectiveness of Thuja occidentalis and Urtica urens in pseudopregnant bitches

Original Article Vet Med Aust Wien Tierarztl Mschr, Volume *, Issue -, 2008, Pages -

Abstract

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Özet

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Cytokines, Growth Factors and Prostaglandin Synthesis in the Uterus of Pregnant and Non-pregnant Bitches: The Features of Placental Sites

Original Article Reproduction in Domestic Animals, Volume *, Issue -, 2009, Pages -

Abstract

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Özet

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Evaluation of Genes Involved in Prostaglandin Action in Equine Endometrium During Estrous Cycle and Early Pregnancy.

Original Article Biology of Reproduction, Volume *, Issue -, 2009, Pages -

Abstract

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Özet

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Time related changes in luteal prostaglandin synthesis and steroidogenic capacity during pregnancy, normal and antiprogestin induced luteolysis in the bitch

Original Article Animal reproduction science, Volume *, Issue -, 2009, Pages -

Abstract

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Özet

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Time related changes in luteal prostaglandin synthesis and steroidogenic capacity during pregnancy, normal and antiprogestin induced luteolysis in the bitch

Original Article Animal reproduction science, Volume *, Issue -, 2009, Pages -

Abstract

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Özet

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Expression of MHC-I and-II in Uterine Tissue from Early Pregnant Bitches

Original Article Reproduction in Domestic Animals, Volume *, Issue -, 2009, Pages -

Abstract

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Özet

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Uterine progesterone receptor and leukaemia inhibitory factor mRNA expression in canine pregnancy

Original Article Reproduction in Domestic Animals, Volume *, Issue -, 2009, Pages -

Abstract

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Özet

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Expression of MHC-I and-II in Uterine Tissue from Early Pregnant Bitches

Original Article Reproduction in Domestic Animals, Volume *, Issue -, 2009, Pages -

Abstract

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Özet

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Uterine progesterone receptor and leukaemia inhibitory factor mRNA expression in canine pregnancy

Original Article Reproduction in Domestic Animals, Volume *, Issue -, 2009, Pages -

Abstract

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Özet

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Cytokines, Growth Factors and Prostaglandin Synthesis in the Uterus of Pregnant and Non-pregnant Bitches: The Features of Placental Sites

Original Article Reproduction in Domestic Animals, Volume 44, Issue 2, 2009, Pages 115-119

Abstract

Uterine tissue from pregnant bitches was investigated by qualitative RT-PCR for the gene expression of local factors potentially important for the implantation of canine embryos. For this purpose, 10 bitches identified as being at the time of implantation or early placentation by means of ultrasonography before ovariohysterectomy (days 20-35, n = 10) provided tissues for comparison to tissue collected in a previous study and identified as early pregnant (n = 10) or non-pregnant (n = 4) by embryo flushing after ovariohysterectomy (days 10-12 after mating; Schäfer-Somi et al. 2008). Uterine tissue was excised from the middle of the left horn from early pregnant and non-pregnant animals, including from interplacental and placentation sites. The following genes were investigated: CD-4, -8; cyclooxygenase (COX)-1, -2; granulocyte macrophage-colony stimulating factor (GM-CSF); hepatocyte growth factor (HGF); insulin-like growth factor (IGF)-1, -2; transforming growth factor (TGF) and tumour necrosis factor (TNF)-alpha; interferon (IFN)-gamma; interleukin (IL)-1beta, -2, -4, -6, -8, -10, -12; leukaemia inhibitory factor (LIF) and leptin. Gene expression for CD-8, COX-1, TGF-beta, HGF, IGF-1, IL-2, -4,-10, IFN-gamma and LIF were detected in the pre-implantation uterus, and all except IL-2 and -10 were still detectable during the implantation and placentation stage. During implantation, mRNA for IGF-2 and GM-CSF were additionally detected. The dioestrous uterus differed from the pregnant uterus because of the absence of CD-8, IL-4 and IFN-gamma and the expression of CD-4, TNF-alpha and IL-6. The results suggest that IL-4, IFN-gamma, CD-8, GM-CSF and IGF-2 are regulated in a pregnancy-specific manner and that GM-CSF and IGF-2 probably have growth supporting and immune modulating functions during implantation of the canine embryo.


Özet

english

Evaluation of Genes Involved in Prostaglandin Action in Equine Endometrium During Estrous Cycle and Early Pregnancy.

Original Article Biology of Reproduction, Volume *, Issue -, 2009, Pages -

Abstract

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Özet

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Treatment of hypersexuality and benign prostatic hypertrophy with delmadinone acetate in intact male dogs

Original Article Turk. J. Vet. Anim. Sci, Volume *, Issue -, 2010, Pages -

Abstract

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Özet

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Canine placenta: a source of prepartal prostaglandins during normal and antiprogestin-induced parturition

Original Article Reproduction, Volume *, Issue -, 2010, Pages -

Abstract

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Özet

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Evaluation cytologique des tumeurs mammaires chez la chienne après biopsie par aspiration à laiguille fine.

Original Article Revue de Medecine Veterinaire, Volume *, Issue -, 2010, Pages -

Abstract

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Özet

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Evaluation of genes involved in prostaglandin action in equine endometrium during estrous cycle and early pregnancy

Original Article Animal reproduction science, Volume *, Issue -, 2010, Pages -

Abstract

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Özet

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Treatment of hypersexuality and benign prostatic hypertrophy with delmadinone acetate in intact male dogs

Original Article Turk. J. Vet. Anim. Sci, Volume *, Issue -, 2010, Pages -

Abstract

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Özet

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Intravaginal application of misoprostol improves pregnancy termination with cabergoline and alfaprostol in dogs. Die intravaginale Applikation von Misopristol verbessert den Trächtigkeitsabbruch mit Cabergolin und Alfaprostol bei Hündinnen.

Original Article Berl. Münch. Tierärztl. Wschr., Volume *, Issue -, 2010, Pages -

Abstract

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Özet

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Evaluation cytologique des tumeurs mammaires chez la chienne après biopsie par aspiration à laiguille fine.

Original Article Revue de Medecine Veterinaire, Volume *, Issue -, 2010, Pages -

Abstract

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Özet

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An inquiry of knowledge, attitudes and practices against pandemic H1N1 influenza among Turkish health care workers: Experience of a single center in Southeast of Turkey

Original Article African Journal of Microbiology Research, Volume *, Issue -, 2010, Pages -

Abstract

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Özet

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Expression of Toll-like Receptors (TLRs) Is Regulated by Early Pregnancy in the Mare Endometrium.

Original Article Biology of Reproduction, Volume *, Issue -, 2010, Pages -

Abstract

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Özet

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Evaluation of genes involved in prostaglandin action in equine endometrium during estrous cycle and early pregnancy

Original Article Animal reproduction science, Volume *, Issue -, 2010, Pages -

Abstract

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Özet

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Cytological Evaluation of canine mammary tumours with fine needle aspiration biopsy

Original Article Revue Méd. Vét, Volume *, Issue -, 2010, Pages -

Abstract

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Özet

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Canine placenta: a source of prepartal prostaglandins during normal and antiprogestin-induced parturition

Original Article Reproduction, Volume *, Issue -, 2010, Pages -

Abstract

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Özet

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Intravaginal application of misoprostol improves pregnancy termination with cabergoline and alfaprostol in dogs. Die intravaginale Applikation von Misopristol verbessert den Trächtigkeitsabbruch mit Cabergolin und Alfaprostol bei Hündinnen.

Original Article Berl. Münch. Tierärztl. Wschr., Volume *, Issue -, 2010, Pages -

Abstract

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Özet

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Cytological Evaluation of canine mammary tumours with fine needle aspiration biopsy

Original Article Revue Méd. Vét, Volume *, Issue -, 2010, Pages -

Abstract

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Özet

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Expression of Toll-like Receptors (TLRs) Is Regulated by Early Pregnancy in the Mare Endometrium.

Original Article Biology of Reproduction, Volume *, Issue -, 2010, Pages -

Abstract

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Özet

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Die intravaginale Applikation von Misopristol verbessert den Trächtigkeitsabbruch mit Cabergolin und Alfaprostol bei Hündinnen

Original Article Berliner und Munchener Tierarztliche Wochenschrift, Volume *, Issue -, 2010, Pages -

Abstract

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Özet

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Die intravaginale Applikation von Misopristol verbessert den Trächtigkeitsabbruch mit Cabergolin und Alfaprostol bei Hündinnen

Original Article Berliner und Munchener Tierarztliche Wochenschrift, Volume *, Issue -, 2010, Pages -

Abstract

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Özet

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An inquiry of knowledge, attitudes and practices against pandemic H1N1 influenza among Turkish health care workers: Experience of a single center in Southeast of Turkey

Original Article African Journal of Microbiology Research, Volume *, Issue -, 2010, Pages -

Abstract

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Özet

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Luteal and placental function in the bitch: spatio-temporal changes in prolactin receptor (PRLr) expression at dioestrus, pregnancy and normal and induced parturition

Original Article Reprod Biol Endocrinol, Volume *, Issue -, 2011, Pages -

Abstract

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Özet

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The intravaginal application of misoprostol improves induction of abortion with aglepristone

Original Article Theriogenology, Volume *, Issue -, 2011, Pages -

Abstract

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Özet

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Expression and functional implications of Peroxisome Proliferator—Activated Receptor Gamma (PPAR?) in canine reproductive tissues during normal pregnancy and parturition and at antiprogestin induced abortion

Original Article Theriogenology, Volume *, Issue -, 2011, Pages -

Abstract

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Özet

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Effects of induction of ovulation with GnRH or hCG on follicular and luteal blood flow in Holstein–Friesian heifers

Original Article Reproduction in domestic animals, Volume *, Issue -, 2011, Pages -

Abstract

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Özet

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Luteal and placental function in the bitch: spatio-temporal changes in prolactin receptor (PRLr) expression at dioestrus, pregnancy and normal and induced parturition

Original Article Reprod Biol Endocrinol, Volume *, Issue -, 2011, Pages -

Abstract

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Özet

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Expression and activity of matrix metalloproteinases in the uterus of bitches after spontaneous and induced abortion

Original Article Reproduction in domestic animals, Volume *, Issue -, 2011, Pages -

Abstract

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Özet

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Expression and activity of matrix metalloproteinases in the uterus of bitches after spontaneous and induced abortion

Original Article Reproduction in domestic animals, Volume *, Issue -, 2011, Pages -

Abstract

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Özet

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Rating of putative housekeeping genes for quantitative gene expression analysis in cyclic and early pregnant equine endometrium

Original Article Animal reproduction science, Volume *, Issue -, 2011, Pages -

Abstract

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Özet

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The intravaginal application of misoprostol improves induction of abortion with aglepristone

Original Article Theriogenology, Volume *, Issue -, 2011, Pages -

Abstract

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Özet

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Rating of putative housekeeping genes for quantitative gene expression analysis in cyclic and early pregnant equine endometrium

Original Article Animal reproduction science, Volume *, Issue -, 2011, Pages -

Abstract

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Özet

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PLS-DA approach for simultaneous evaluation of genes involved in luteolysis in equine endometrium during estrous cycle and early pregnancy

Original Article Current Opinion in Biotechnology, Volume *, Issue -, 2011, Pages -

Abstract

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Özet

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Effects of induction of ovulation with GnRH or hCG on follicular and luteal blood flow in Holstein–Friesian heifers

Original Article Reproduction in domestic animals, Volume *, Issue -, 2011, Pages -

Abstract

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Özet

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Expression and functional implications of Peroxisome Proliferator—Activated Receptor Gamma (PPAR?) in canine reproductive tissues during normal pregnancy and parturition and at antiprogestin induced abortion

Original Article Theriogenology, Volume *, Issue -, 2011, Pages -

Abstract

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Özet

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Effect of subsequent two short-term, short-term, and long-term progestagen treatments on fertility of Awassi ewes out of the breeding season

Original Article Ankara Üniv. Vet. Fak. Derg, Volume *, Issue -, 2011, Pages -

Abstract

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Özet

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PLS-DA approach for simultaneous evaluation of genes involved in luteolysis in equine endometrium during estrous cycle and early pregnancy

Original Article Current Opinion in Biotechnology, Volume *, Issue -, 2011, Pages -

Abstract

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Özet

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Effect of subsequent two short-term, short-term, and long-term progestagen treatments on fertility of Awassi ewes out of the breeding season

Original Article Ankara Üniv. Vet. Fak. Derg, Volume *, Issue -, 2011, Pages -

Abstract

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Özet

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Beneficial effects of Beta-carotene injections prior to treatment with PGF (2) alpha on the fertility of postpartum dairy cows

Original Article Revue de Medecine Veterinaire, Volume *, Issue -, 2012, Pages -

Abstract

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Özet

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Uterine involution, follicle development and concentrations of plasma progesterone, 20?-OH-progesterone and total estrogen levels during the postpartum period in anatolian donkeys

Original Article Kafkas Univ Vet Fak Derg, Volume *, Issue -, 2012, Pages -

Abstract

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Özet

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The effectiveness of combined preventive treatment with Ceftiofur, Oxytocin and PGF 2? on fertility parameters in cows

Original Article Revue Méd. Vét, Volume *, Issue -, 2012, Pages -

Abstract

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Özet

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Expression of Epidermal Growth Factor (EGF) and Heparin-Binding EGF (HB-EGF) mRNA in Mare Endometrium

Original Article Kafkas Universitesi Veteriner Fakultesi Dergisi, Volume *, Issue -, 2012, Pages -

Abstract

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Özet

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Uterine involution, follicle development and concentrations of plasma progesterone, 20?-OH-progesterone and total estrogen levels during the postpartum period in anatolian donkeys

Original Article Kafkas Univ Vet Fak Derg, Volume *, Issue -, 2012, Pages -

Abstract

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Özet

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Is apoptosis a regulatory mechanism during early canine pregnancy?

Original Article Reproduction in Domestic Animals, Volume *, Issue -, 2012, Pages -

Abstract

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Özet

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Expression of Epidermal Growth Factor (EGF) and Heparin-Binding EGF (HB-EGF) mRNA in Mare Endometrium

Original Article Kafkas Universitesi Veteriner Fakultesi Dergisi, Volume *, Issue -, 2012, Pages -

Abstract

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Özet

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The Change in Luteal Blood Flow and Luteal Size after Beta Carotene and GnRH Injections in Early Pregnant Dairy Cows

Original Article Kafkas Üniversitesi Veteriner Fakültesi Dergisi, Volume *, Issue -, 2012, Pages -

Abstract

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Özet

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Is apoptosis a regulatory mechanism during early canine pregnancy?

Original Article Reproduction in Domestic Animals, Volume *, Issue -, 2012, Pages -

Abstract

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Özet

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Beneficial effects of Beta-carotene injections prior to treatment with PGF (2) alpha on the fertility of postpartum dairy cows

Original Article Revue de Medecine Veterinaire, Volume *, Issue -, 2012, Pages -

Abstract

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Özet

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The Change in Luteal Blood Flow and Luteal Size after Beta Carotene and GnRH Injections in Early Pregnant Dairy Cows

Original Article Kafkas Üniversitesi Veteriner Fakültesi Dergisi, Volume *, Issue -, 2012, Pages -

Abstract

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Özet

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The effectiveness of combined preventive treatment with Ceftiofur, Oxytocin and PGF 2? on fertility parameters in cows

Original Article Revue Méd. Vét, Volume *, Issue -, 2012, Pages -

Abstract

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Özet

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Expression of platelet activating factors and its receptor in cat uterus during early pregnancy

Original Article Ankara Univ Vet Fak Derg, Volume *, Issue -, 2013, Pages -

Abstract

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Özet

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Clinical and Endocrine Short-Term Effects of GnRH Analogue Deslorelin in Prepubertal Bitches: Does A “Flare-up” Occur?

Original Article Kafkas Univ Vet Fak Derg, Volume *, Issue -, 2013, Pages -

Abstract

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Özet

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The effectiveness of supplemental administration of progesterone with GnRH, hCG and PGF 2? on the fertility of Tuj sheep during the non-breeding season

Original Article Small Ruminant Research, Volume *, Issue -, 2013, Pages -

Abstract

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Özet

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Clinical and Endocrine Short-Term Effects of GnRH Analogue Deslorelin in Prepubertal Bitches: Does A “Flare-up” Occur?

Original Article Kafkas Univ Vet Fak Derg, Volume *, Issue -, 2013, Pages -

Abstract

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Özet

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Expression of platelet activating factors and its receptor in cat uterus during early pregnancy

Original Article Ankara Univ Vet Fak Derg, Volume *, Issue -, 2013, Pages -

Abstract

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Özet

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Expression of enzymes and receptors of leukotriene pathway genes in equine endometrium during the estrous cycle and early pregnancy

Original Article Theriogenology, Volume *, Issue -, 2013, Pages -

Abstract

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Özet

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Expression of enzymes and receptors of leukotriene pathway genes in equine endometrium during the estrous cycle and early pregnancy

Original Article Theriogenology, Volume *, Issue -, 2013, Pages -

Abstract

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Özet

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Quantitative software analysis of ultrasonographic textures in experimental testicular torsion

Original Article Eur J Pediatr Surg, Volume *, Issue -, 2013, Pages -

Abstract

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Özet

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Expression of factors involved in decidualization and implantation in canine early pregnant uterus

Original Article Reproductive Biology, Volume *, Issue -, 2013, Pages -

Abstract

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Özet

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Vascular Endothelial (VEGF) and Epithelial Growth Factor (EGF) as Well as Platelet-Activating Factor (PAF) and Receptors are Expressed in the Early Pregnant Canine Uterus

Original Article Reproduction in Domestic Animals, Volume *, Issue -, 2013, Pages -

Abstract

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Özet

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The effectiveness of supplemental administration of progesterone with GnRH, hCG and PGF 2? on the fertility of Tuj sheep during the non-breeding season

Original Article Small Ruminant Research, Volume *, Issue -, 2013, Pages -

Abstract

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Özet

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Vascular Endothelial (VEGF) and Epithelial Growth Factor (EGF) as Well as Platelet-Activating Factor (PAF) and Receptors are Expressed in the Early Pregnant Canine Uterus

Original Article Reproduction in Domestic Animals, Volume *, Issue -, 2013, Pages -

Abstract

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Özet

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Expression of factors involved in decidualization and implantation in canine early pregnant uterus

Original Article Reproductive Biology, Volume *, Issue -, 2013, Pages -

Abstract

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Özet

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Quantitative software analysis of ultrasonographic textures in experimental testicular torsion

Original Article Eur J Pediatr Surg, Volume *, Issue -, 2013, Pages -

Abstract

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Özet

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Suppression of Fertility in Pre-pubertal Dogs and Cats

Original Article Reproduction in Domestic Animals, Volume *, Issue -, 2014, Pages -

Abstract

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Özet

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The effect of a misapplied progesterone-releasing intravaginal device on fertility in a Holstein-Friesian cow.

Original Article Veterinarski arhiv, Volume *, Issue -, 2014, Pages -

Abstract

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Özet

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Clinical evaluation of different applications of misoprostol and aglepristone for induction of abortion in bitches

Original Article Theriogenology, Volume *, Issue -, 2014, Pages -

Abstract

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Özet

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The effects of aglepristone alone and in combination with cloprostenol on hormonal values during termination of mid-term pregnancy in bitches

Original Article Animal Reproduction Science, Volume 146, Issue 3-4, 2014, Pages 210-217

Abstract

This study was designed to assess endocrine changes associated with termination of mid-term pregnancy after use of two different protocols. For this purpose we compared the effects of aglepristone (AGL) alone and in combination with cloprostenol (CLO) on serum concentrations of progesterone (P4), estradiol (E2) and relaxin (RLN) measured at short-term intervals during the abortion period in bitches. Fourteen pregnant bitches between day 25 and 32 of gestation were used in the study. In the AGL group (n = 7), aglepristone was administered solely (10 mg/kg body weight (BW), subcutaneously, once daily on two consecutive days) whereas in the AGL-CLO group (n = 7), aglepristone (dosage as in AGL group) and cloprostenol (1 µg/kg BW, subcutaneously, same with aglepristone) were combined. All pregnancies were successfully terminated 5.2 ± 1.6 days after initiation of treatments, which was significant in both groups (P > 0.05). At the time of the start of abortion (SA) and the end of abortion (EA), the mean P4 concentrations were 26.6 ± 7.3 and 12.0 ± 6.4 ng/ml in AGL group, and 2.7 ± 0.7 and 0.9 ± 0.1 ng/ml, in AGL-CLO group, respectively (P < 0.01). Serum E2 concentrations were significantly higher (P < 0.05) in AGL group at 42, 48, 54 h and SA after initiation of treatment. In the AGL-CLO group, serum RLN concentrations did not significantly change from the initiation of treatment to EA (P > 0.05). However, markedly higher RLN concentrations (P < 0.05) were observed in the AGL group at 48 h (1.5 ± 0.7 ng/ml) and at SA (1.6 ± 0.5 ng/ml). The results of the present study indicate that changes in the hormonal concentrations affect the mechanism of abortion in different ways. Further in depth studies investigating changes in the expression of hormone receptors inside the ovary, endometrium and placenta might be helpful to our understanding of the endocrinological differences observed in this study.


Özet

Yayın ingilizcedir.

Tarantula cubensis extract changes the degree of apoptosis and mitosis in canine mammary adenocarcinomas.

Original Article Journal of veterinary science, Volume *, Issue -, 2014, Pages -

Abstract

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Özet

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Bewertung von Echotexturparametern des Endometriums und zytologischen Zervixbefunden bei Kühen während und nach Behandlung einer Endometritis

Original Article Tierärztliche Praxis Großtiere, Volume *, Issue -, 2014, Pages -

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Clinical evaluation of different applications of misoprostol and aglepristone for induction of abortion in bitches

Original Article Theriogenology, Volume *, Issue -, 2014, Pages -

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The effect of a misapplied progesterone-releasing intravaginal device on fertility in a Holstein-Friesian cow.

Original Article Veterinarski arhiv, Volume *, Issue -, 2014, Pages -

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Özet

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Suppression of Fertility in Pre-pubertal Dogs and Cats

Original Article Reproduction in Domestic Animals, Volume *, Issue -, 2014, Pages -

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Expression of genes involved in the embryo–maternal interaction in the early-pregnant canine uterus

Original Article Reproduction, Volume *, Issue -, 2014, Pages -

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Evaluation of endometrial echotexture and cervical cytology in cows during and after treatment of endometritis

Original Article Tierärztliche Praxis Großtiere, Volume *, Issue -, 2014, Pages -

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Özet

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Tarantula cubensis extract changes the degree of apoptosis and mitosis in canine mammary adenocarcinomas.

Original Article Journal of veterinary science, Volume *, Issue -, 2014, Pages -

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Özet

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Clinical evaluation of different applications of misoprostol and aglepristone for induction of abortion in bitches

Original Article Theriogenology, Volume 81, Issue 7, 2014, Pages 947-951

Abstract

The aim of the present study was to compare the clinical and endocrinological effects of different applications of misoprostol (MIS) and aglepristone (AGL) for the induction of abortion in bitches. For this purpose, 28 healthy pregnant bitches from different breeds, ages, body weights (Body weigt, BWs, 10–40 kg), and between Days 25 to 35 of gestation were used. Bitches were randomly assigned to four groups. In group 1 (GI, n = 7), AGL (10 mg/kg BW, s.c. on 2 consecutive days); in group 2 (GII, n = 7), AGL (as in GI), intravaginal MIS (IVag, 200 µg for bitches with ?20 kg BW, 400 µg for bitches with >20 kg BW, daily intravaginally until completion of abortion); in group 3 (GIII, n = 7), AGL (as in GI), ICVag (as in GII), per os MIS (400 µg for bitches with ?20 kg BW, 800 µg for bitches with >20 kg BW, daily orally, until completion of abortion); in group 4 (GIV, n = 7), AGL (as in GI), per os MIS (as GIII) were used. Clinical, vaginal, and ultrasonographic examinations were performed daily until abortion was completed. For measurement of serum progesterone, blood samples were collected in all groups immediately after the first AGL administration and every other day until completion of abortion. No statistical differences were found between groups concerning the duration until completion of abortion after treatment (nonsignificant); however, in GII, one bitch completed abortion 2 days after the start of treatment.


Özet

Yayın ingilizcedir.

Evaluation of endometrial echotexture and cervical cytology in cows during and after treatment of endometritis

Original Article Tierärztliche Praxis Großtiere, Volume *, Issue -, 2014, Pages -

Abstract

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Özet

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Expression of genes involved in the embryo–maternal interaction in the early-pregnant canine uterus

Original Article Reproduction, Volume *, Issue -, 2014, Pages -

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Özet

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The effects of aglepristone alone and in combination with cloprostenol on hormonal values during termination of mid-term pregnancy in bitches

Original Article Animal reproduction science, Volume *, Issue -, 2014, Pages -

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Özet

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Bewertung von Echotexturparametern des Endometriums und zytologischen Zervixbefunden bei Kühen während und nach Behandlung einer Endometritis

Original Article Tierärztliche Praxis Großtiere, Volume *, Issue -, 2014, Pages -

Abstract

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Özet

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The effects of aglepristone alone and in combination with cloprostenol on hormonal values during termination of mid-term pregnancy in bitches

Original Article Animal reproduction science, Volume *, Issue -, 2014, Pages -

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Özet

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Expression of genes involved in the embryo–maternal interaction in the early-pregnant canine uterus

Original Article Reproduction, Volume 147, Issue DOI: 10.1530/REP-13-0648 , 2014, Pages 703-717

Abstract

Although there is no acute luteolytic mechanism in the absence of pregnancy in the bitch, a precise and well-timed embryo–maternal interaction seems to be required for the initiation and maintenance of gestation. As only limited information is available about these processes in dogs, in this study, the uterine expression of possible decidualization markers was investigated during the pre-implantation stage (days 10–12) of pregnancy and in the corresponding nonpregnant controls. In addition, the expression of selected genes associated with blastocyst development and/or implantation was investigated in embryos flushed from the uteri of bitches used for this study (unhatched and hatched blastocysts). There was an upregulated expression of prolactin receptor (PRLR) and IGF2 observed pre-implantation. The expression of PRL and of IGF1 was unaffected, and neither was the expression of progesterone- or estrogen receptor b(ESR2). In contrast, (ESR1) levels were elevated during early pregnancy. Prostaglandin (PG)-system revealed upregulated expression of PGE2-synthase and its receptors, PTGER2 and PTGER4 and of the PG-transporter. Elevated levels of AKR1C3 mRNA, but not the protein itself, were noted. Expression of prostaglandin-endoperoxide synthase 2 (PTGS2) remained unaffected. Most of the transcripts were predominantly localized to the uterine epithelial cells, myometrium and, to a lesser extent, to the uterine stroma. PGES (PTGES) mRNA was abundantly expressed in both groups of embryos and appeared higher in the hatched ones. The expression level of IGF2 mRNA appeared higher than that of IGF1 mRNA in hatched embryos. In unhatched embryos IGF1, IGF2, and PTGS2mRNA levels were below the detection limit.


Özet

Yayın ingilizcedir

Evaluation of endometrial echotexture and cervical cytology in cows during and after treatment of endometritis

Original Article Tierärztliche Praxis Großtiere, Volume 42(G), Issue x.doi.org/10.15653/TPG-140473, 2014, Pages 11-18

Abstract

Objective: The aim of this study was to evaluate changes in the endome- trium by using echotexture parameters during and after treatment of en- dometritis with intrauterine administration of an intra ute rine antiseptic solution (Lotagen®, 3% metacresolsulphonic acid and formaldehyde) in cows which became pregnant after treatment. Material and methods: According to the severity of endometritis 21 cows were divided into three groups: E1 (slight, n = 7), E2 (moderate, n = 8), E3 (severe, n = 6). The control group (C, n = 11) consisted of cows without endometritis that did not receive an intrauterine medication. A software (Bs200 Pro®) was used to evaluate echotexture parameters Contrast (CON), Gradient (GR), Homogeneity (HOM), Mean Gray Level (MGL) of images taken during the examinations at hours (h) 0, 1 and 6 and days (d) 2, 3, 5 and 10. Results: At 0 h, GR was significantly lower in group E2 than in groups E1 and C (p < 0.05). There was an increase in GR values between 0 h and 10 d in group E2 and E3, but a decrease during the same time interval in group C (p < 0.05). In contrast, CON values of group E2 were lower (p < 0.05) at 0 h compared to other timepoints of examination and lower than in group C. HOM values were lower (p < 0.05) in groups E1, E2 and E3 than in group C on d 5 and d 10. HOM values were higher at 1 h compared to 6 h, d 2 and d 10 in group E3 (p < 0.05). By contrast to GR values, HOM values were higher in group C at 6 h and d 10 than they were in group E3. MGL values of group E2 were higher (p < 0.05) than in group C until d 10 and higher (p < 0.05) in group E3 than in group C at 6 h after treat- ment. In group E2 an increase of MGL values until d 2 was followed by a decrease (p < 0.05). Conclusion: Echotexture parameters determined by the evaluation of sonographic B-mode images reflect changes in the en- dometrium and could be used for the evaluation of the recovery period after treatment of endometritis.


Özet

Yayın ingilizcedir.

The effects of Cosynch-56 protocol on pregnancy rates of cows and heifers presynchronized with a single dose of PGF (2 alpha)

Original Article REVUE DE MEDECINE VETERINAIRE, Volume *, Issue -, 2015, Pages -

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Gene expression profiles of some cytokines, growth factors, receptors, and enzymes (GM-CSF, IFN?, MMP-2, IGF-II, EGF, TGF-ß, IGF-IIR) during pregnancy in the cat uterus

Original Article Theriogenology, Volume *, Issue -, 2015, Pages -

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Özet

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GnRH and its receptor (GnRH-R) are expressed in the canine placenta and uterus

Original Article Theriogenology, Volume *, Issue -, 2015, Pages -

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Özet

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Investigation of the Effects of Acupuncture Stimulation on the Size and Blood Flow of Corpus Luteum and Progesterone Levels in Dairy Cows

Original Article Kafkas Univ Vet Fak Derg, Volume 21, Issue 6, 2015, Pages 877-883

Abstract

In this study, effect of acupuncture (AP) on the luteal size (LS), luteal blood flow (LBF) and progesterone (P4) levels were investigated in the presence of corpus luteum (CL) in cows. Seven days after 14-days interval PGF2? estrus synchronization protocol, CL positive animals were assigned either to a control group (AP–, n=10) or to an AP group (AP+, n=10) stimulated by using B22 and B23 sensitive acupoints. LS and LBF examinations were carried out before the stimulation (0h) and at 1st, 3rd, 6th hour on d7 and thereafter on d9, d10, d11, d12 and d13 following the AP stimulation in each group with a portable color Doppler ultrasonography. Blood samples for P 4 measurement were collected during each examination. There was no significant difference in LS, LBF, or P 4 mean values between groups. However, LBF significantly increased at 6h after stimulation (P<0.05) in AP+ group but it increased at d11 in AP– group (P<0.05). The significant increase in LS was observed earlier in AP+ group (on d9; P<0.01) than AP– (on d11; P<0.05). Serum P 4 concentrations increased at 3h, d9 and d10 in AP+ group (P<0.05), however a significant difference was only observed at 3h in AP– group (P<0.05). In conclusion, AP stimulation induces earlier increases in LS, LBF and P4 parameters in cows during luteal phase


Özet

Bu çalışmada akupunkturun (AP) ineklerde korpus luteum (CL) varlığında luteal büyüklük (LS), luteal kan akımı (LBF) ve progesteron (P4) seviyeleri üzerindeki etkisi incelendi. 14 gün aralıklı PGF2? östrus senkronizasyon protokolünden 7 gün sonra, CL tespit edilen hayvanlar kontrol (AP–, n=10) ve duyarlı B22 ve B23 kullanılarak stimüle edilen akupunktur gruplarına ayrıldı (AP+, n=10). LS ve LBF incelemeleri taşınabilir bir renkli Doppler ultrasonografi ile 7. günde stimülasyon öncesi (0. saat), izleyen 1, 3, 6. saatler ve 9, 10, 11, 12 ve 13. günlerde yapıldı. Her muayenede P 4 ölçümleri için kan örnekleri alındı. Gruplar arasında LS, LBF ve P 4 ortalama değerleri farklı değildi. Bununla birlikte, LBF AP+ grubunda stimülasyon sonrası 6. saatte (P<0.05) ancak AP– grubunda 11. günde arttı (P<0.05). LS’deki önemli artış ise AP+ grubunda (9. gün; P<0.01), AP– grubuna göre (11. gün; P<0.05) daha erken gözlendi. Serum P 4 konsantrasyonları AP+ grubunda 3. saat, 9. gün ve 10. günde artış gösterdi (P<0.05). Ancak AP– grubunda sadece 3. saatte önemli değişim gözlendi (P<0.05). Sonuç olarak, luteal faz sırasında akupunktur stimülasyonu LS, LBF ve P4 değerlerinde daha erken artışa neden olmakta

The effects of Cosynch-56 protocol on pregnancy rates of cows and heifers presynchronized with a single dose of PGF 2?

Original Article Revue Méd. Vét. , Volume 166, Issue 3-4, 2015, Pages 90-95

Abstract

The objective of this study was to evaluate pregnancy rates to timed artificial insemination (TAI) following presynchronization with a single dose of PGF2? ten days before CoSynch-56 protocol in Brown Swiss crossbred cows and heifers. Group I (GI) cows (n=89) and heifers (n=39) received PGF2? ten days prior to Cosynch-56 protocol while Group II (GII) cows (n=82) and heifers (n=38) received CoSynch-56 protocol only. Pregnancy was evaluated using ultrasonography 30-35 days after TAI. Pregnancy rates did not differ significantly between GI and GII (34.4% and 28.3 %, respectively, P>0.05). However, pregnancy rates differed significantly (P<0.05) between cows and heifers in GII (34.1% and 15.7%, respectively). Furthermore, pregnancy rates of heifers in GI was significantly higher than that of heifer in GII (P<0.01, 41.0% and 15.7%, respectively). Notably, pregnancy was not achieved in GII heifers with plasma P4 values < 1ng/ml. In conclusion, presynchronization with PGF2? before Cosynch-56 protocol did not enhance pregnancy rates in Brown Swiss cows but did in heifers. Also, high P4 levels may enhance overall pregnancy rates of cows and heifers subjected to the Cosynch-56 protocol.


Özet

Yayın ingilice ve Fransızcadır. İngilizce özet aşağıdadır.

Clinical use of deslorelin implants for the long-term contraception in prepubertal bitches: Effects on epiphyseal closure, body development, and time to puberty

Original Article Theriogenology, Volume *, Issue -, 2015, Pages -

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Özet

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Effect of deslorelin on testicular function, serum dihydrotestosterone and oestradiol concentrations during and after suppression of sexual activity in tom cats

Original Article Journal of feline medicine and surgery, Volume *, Issue -, 2015, Pages -

Abstract

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Özet

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GnRH and its receptor (GnRH-R) are expressed in the canine placenta and uterus

Original Article Theriogenology, Volume 84, Issue 9, 2015, Pages 1482-1489

Abstract

In reproductive tissues, GnRH participates in the regulation of cell growth and proliferation by direct binding to the GnRH-R, which is essential for embryo implantation. However, there is no study on the expression and cellular localization of GnRH and GnRH-R in the canine uterus and placenta. Therefore, bitches were ovariohysterectomized 10 to 12 days after mating (vaginal cytology and progesterone measurement), the uteri were flushed, and if embryos were detectable, bitches were allocated to the embryo positive group (E-pos.; preimplantation, n = 5). Other bitches were operated at later stages and, dependent on the gestational age, either allotted to the post-implantation group (Day 18–25 after mating, n = 9), or the mid-gestation group (Day 30–40 after mating, n = 3). Dogs negative in embryo flushing served as controls (E-neg.; controls, n = 5). Samples of the entire uterine wall were taken from the middle of the horn in E-neg. and E-pos. groups, and from placental and interplacental uterine sites in post-implantation and mid-gestation groups. GnRH-R expression was localized at the mRNA and protein levels by immunohistochemistry and in situ hybridization. The expression of GnRH and GnRH-R mRNA was assessed by semiquantitative polymerase chain reaction. Additionally, both GnRH and GnRH-R mRNA were expressed in all tissues examined until mid-gestation. Relative expression of GnRH was higher than that of GnRH-R (P < 0.05). During the post-implantation stage, GnRH-R expression was significantly higher in uteroplacental than in interplacental tissues. In the uterus, GnRH-R stained strongly in the surface and glandular epithelial cells, and seemed to be weaker in myometrium and stroma. Placental signals were predominantly localized in fetal trophoblast cells and to a lesser extent in maternal decidual cells. These findings suggest a local regulatory function of GnRH during early canine pregnancy.


Özet

Yayın ingilizcedir.

GnRH and its receptor (GnRH-R) are expressed in the canine placenta and uterus

Original Article Theriogenology, Volume 84, Issue -, 2015, Pages 1482-1489

Abstract

In reproductive tissues, GnRH participates in the regulation of cell growth and proliferation by direct binding tothe GnRH-R, which is essential for embryo implantation. However, there is no study on the expression and cellular localization of GnRH and GnRH-R in the canine uterus and placenta. Therefore, bitches were ovariohysterectomized 10 to 12 days after mating (vaginal cytology and progesterone measurement), the uteri were flushed, and if embryos were detectable, bitches were allocated to the embryo positive group (E-pos.; preimplantation, n=5). Other bitches were operated at later stages and, dependent on the gestational age, either allotted to the post-implantation group (Day 18–25 after mating,n=9), or the mid-gestation group (Day 30–40 after mating, n=3). Dogs negative in embryo flushing served as controls (E-neg.; controls, n=5). Samples of the entire uterine wall were taken from the middle of the horn in E-neg. and E-pos. groups, and from placental and interplacental uterine sites in post-implantation and mid-gestation groups. GnRH-R expression was localized at the mRNA and protein levels by immunohistochemistry and in situ hybridization. The expression of GnRH and GnRH-RmRNA was assessed by semi-quantitative polymerase chain reaction. Additionally, both GnRH and GnRH-RmRNA were expressed in all tissues examined until mid-gestation. Relative expression of GnRH was higher than that of GnRH-R (P<0.05). During the post-implantation stage, GnRH-R expression was significantly higher in uteroplacental than in interplacental tissues. In the uterus, GnRH-R stained strongly in the surface and glandular epithelial cells, and seemed to be weaker in myometrium and stroma. Placental signals were predominantly localized in fetal trophoblast cells and to a lesser extent in maternal decidual cells. These findings suggest a local regulatory function of GnRH during early canine pregnacy.


Özet

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Effect of deslorelin on testicular function, serum dihydrotestosterone and oestradiol concentrations during and after suppression of sexual activity in tom cats

Original Article Journal of feline medicine and surgery, Volume *, Issue -, 2015, Pages -

Abstract

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Özet

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The effects of Cosynch-56 protocol on pregnancy rates of cows and heifers presynchronized with a single dose of PGF (2 alpha)

Original Article REVUE DE MEDECINE VETERINAIRE, Volume *, Issue -, 2015, Pages -

Abstract

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Özet

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Gene expression profiles of some cytokines, growth factors, receptors, and enzymes (GM-CSF, IFN?, MMP-2, IGF-II, EGF, TGF-ß, IGF-IIR) during pregnancy in the cat uterus

Original Article Theriogenology, Volume *, Issue -, 2015, Pages -

Abstract

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Özet

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Expression of hypoxia-inducible factors and vascular endothelial growth factor during pregnancy in the feline uterus

Original Article Theriogenology, Volume *, Issue -, 2015, Pages -

Abstract

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Özet

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Clinical use of deslorelin implants for the long-term contraception in prepubertal bitches: Effects on epiphyseal closure, body development, and time to puberty

Original Article Theriogenology, Volume *, Issue -, 2015, Pages -

Abstract

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Özet

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Investigation of the Effects of Acupuncture Stimulation on the Size and Blood Flow of Corpus Luteum and Progesterone Levels in Dairy Cows

Original Article Kafkas Univ Vet Fak Derg, Volume *, Issue DOI: 10.9775/kvfd.2015.13803, 2015, Pages -

Abstract

In this study, effect of acupuncture (AP) on the luteal size (LS), luteal blood flow (LBF) and progesterone (P4) levels were investigated in the presence of corpus luteum (CL) in cows. Seven days after 14-days interval PGF2? estrus synchronization protocol, CL positive animals were assigned either to a control group (AP–, n=10) or to an AP group (AP+, n=10) stimulated by using B22 and B23 sensitive acupoints. LS and LBF examinations were carried out before the stimulation (0h) and at 1st, 3rd, 6th hour on d7 and thereafter on d9, d10, d11, d12 and d13 following the AP stimulation in each group with a portable color Doppler ultrasonography. Blood samples for P4 measurement were collected during each examination. There was no significant difference in LS, LBF, or P4 mean values between groups. However, LBF significantly increased at 6h after stimulation (P<0.05) in AP+ group but it increased at d11 in AP– group (P<0.05). The significant increase in LS was observed earlier in AP+ group (on d9; P<0.01) than AP– (on d11; P<0.05). Serum P4 concentrations increased at 3h, d9 and d10 in AP+ group (P<0.05), however a significant difference was only observed at 3h in AP– group (P<0.05). In conclusion, AP stimulation induces earlier increases in LS, LBF and P4 parameters in cows during luteal phase.


Özet

Bu çalışmada akupunkturun (AP) ineklerde korpus luteum (CL) varlığında luteal büyüklük (LS), luteal kan akımı (LBF) ve progesteron (P4) seviyeleri üzerindeki etkisi incelendi. 14 gün aralıklı PGF2? östrus senkronizasyon protokolünden 7 gün sonra, CL tespit edilen hayvanlar kontrol (AP–, n=10) ve duyarlı B22 ve B23 kullanılarak stimüle edilen akupunktur gruplarına ayrıldı (AP+, n=10). LS ve LBF incelemeleri taşınabilir bir renkli Doppler ultrasonografi ile 7. günde stimülasyon öncesi (0. saat), izleyen 1, 3, 6. saatler ve 9, 10, 11, 12 ve 13. günlerde yapıldı. Her muayenede P4 ölçümleri için kan örnekleri alındı. Gruplar arasında LS, LBF ve P4 ortalama değerleri farklı değildi. Bununla birlikte, LBF AP+ grubunda stimülasyon sonrası 6. saatte (P<0.05) ancak AP– grubunda 11. günde arttı (P<0.05). LS’deki önemli artış ise AP+ grubunda (9. gün; P<0.01), AP– grubuna göre (11. gün; P<0.05) daha erken gözlendi. Serum P4 konsantrasyonları AP+ grubunda 3. saat, 9. gün ve 10. günde artış gösterdi (P<0.05). Ancak AP– grubunda sadece 3. saatte önemli değişim gözlendi (P<0.05). Sonuç olarak, luteal faz sırasında akupunktur stimülasyonu LS, LBF ve P4 değerlerinde daha erken artışa neden olmaktadır

Expression of hypoxia-inducible factors and vascular endothelial growth factor during pregnancy in the feline uterus.

Original Article Theriogenology, Volume 84, Issue 1, 2015, Pages 24-33

Abstract

Hypoxia-inducible factors (HIFs) and vascular endothelial growth factor (VEGF) have critical roles during the development of the fetomaternal unit. The HIFs regulate placentation and vascularization by stimulation of VEGF gene expression. This study aimed to investigate the expression profiles of HIF gene family and VEGF in the cat uterus during pregnancy. Tissue samples of the whole uterine wall were collected after ovariohysterectomy and allocated to the following groups: embryo positive (group 1 [G1], n = 7, 7 days after mating), early pregnancy (group 2 [G2], n = 7, 20 days after mating), mid-pregnancy (group 3 [G3], n = 7, 24 days after mating), late pregnancy (group 4 [G4], n = 7, 30–45 days after mating), and oocyte positive groups (group 5 [G5], n = 7, 7 days after induction of ovulation with GnRH analog). Relative mRNA levels were determined by real-time polymerase chain reaction. As housekeeping gene, glyceraldehyde-3-phosphate dehydrogenase was used. The relative gene expression of HIF1A in G5 was found to be significantly higher than that of other groups (G1, G2, G3, and G4) (P < 0.05). In addition, the expression of HIF2A in G5 was higher than that of G1 and HIF2A gene expression at placentation sites of G4 was higher than in G1, G2, and G3 (P < 0.05). Immunohistochemistry indicated that HIF1A, HIF2A, and VEGF expressions were observed in different cell types of uterine and placental tissues in late pregnancy and oocyte groups. The expression of HIF3A did not change significantly in any group investigated. These observations suggest that HIFs and VEGF may play a role in the establishment and development of pregnancy.


Özet

Yayın ingilizcedir.

Expression of hypoxia-inducible factors and vascular endothelial growth factor during pregnancy in the feline uterus

Original Article Theriogenology, Volume 84, Issue dx.doi.org/10.1016/j.theriogenology.2015.02.009, 2015, Pages 24-33

Abstract

Hypoxia-inducible factors (HIFs) and vascular endothelial growth factor (VEGF) have critical roles during the development of the fetomaternal unit. The HIFs regulate placentation and vascularization by stimulation of VEGF gene expression. This study aimed to investigate the expression profiles of HIF gene family and VEGF in the cat uterus during pregnancy. Tissue samples of the whole uterine wall were collected after ovariohysterectomy and allocated to the following groups: embryo positive (group 1 [G1], n = 7, 7 days after mating), early pregnancy (group 2 [G2], n = 7, 20 days after mating), mid-pregnancy (group 3 [G3], n = 7, 24 days after mating), late pregnancy (group 4 [G4], n = 7, 30–45 days after mating), and oocyte positive groups (group 5 [G5], n ¼ 7, 7 days after induction of ovulation with GnRH analog). Relative mRNA levels were determined by real-time polymerase chain reaction. As housekeeping gene, glyceraldehyde-3-phosphate dehydrogenase was used. The relative gene expression of HIF1A in G5 was found to be significantly higher than that of other groups (G1, G2, G3, and G4) (P < 0.05). In addition, the expression of HIF2A in G5 was higher than that of G1 and HIF2A gene expression at placentation sites of G4 was higher than in G1, G2, and G3 (P < 0.05). Immunohistochemistry indicated that HIF1A, HIF2A, and VEGF expressions were observed in different cell types of uterine and placental tissues in late pregnancy and oocyte groups. The expression of HIF3A did not change significantly in any group investigated. These observations suggest that HIFs and VEGF may play a role in the establishment and development of pregnancy


Özet

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Tarantula cubensis extract alters the degree of apoptosis and mitosis in canine mammary adenocarcinomas

Original Article Journal of veterinary Science (J Vet Sci), Volume 16, Issue 2, 2015, Pages 213-219

Abstract

In the present study, 13 clinical cases of canine mammary adenocarcinoma were evaluated in order to understand the effect of Tarantula cubensis extract (TCE) on tumor tissue. Punch biopsies were taken from the tumors before treatment with TCE. Subcutaneous injections of TCE were administered three times at weekly intervals (3 mL per dog). Between days 7 and 10 after the third injection, the tumor masses were extirpated by complete unilateral mastectomy. Pre- and post-treatment tumor tissues were immunohistochemically assessed. The expression of B-cell lymphoma 2 (Bcl-2) was found to be higher in pre-treatment compared to post-treatment tissues (p < 0.01) whereas Ki-67 expression was lower in post-treatment tissues (p < 0.01). No significant differences in fibroblast growth factor or vascular endothelial growth factor expression were observed between pre- and post-treatment tissues (p > 0.05). The apoptotic index was determined to be low before treatment and increased during treatment. These results suggest that TCE may be effective for controlling the local growth of canine mammary adenocarcinoma by regulating apoptosis.


Özet

Yayın ingilzcedir.

Effect of deslorelin on testicular function, serum dihydrotestosterone and oestradiol concentrations during and after suppression of sexual activity in tom cats

Original Article Journal of Feline Medicine and Surgery, Volume DOI: 10.1177/1098612X15615381, Issue DOI: 10.1177/1098612X15615381, 2015, Pages 1-9

Abstract

Objectives The aim of the study was to evaluate the efficacy of a 4.7 mg deslorelin implant in tom cats. Methods Nine mature male cats were included in the deslorelin group and five cats in the control group. Before the study started, all cats were confirmed to have distinct sexually dimorphic behaviour. Blood samples were taken on the implantation day, at day 7 and at day 15, then monthly, in order to measure serum dihydrotestosterone (DHT) and 17beta(ß)-oestradiol concentrations. The deslorelin group (n = 9) was divided into two subgroups: five cats (cats 1–5) were neutered in the postimplantation period during suppression of sexually dimorphic behaviour, and four cats (cats 6–9) were neutered after re-expression of sexually dimorphic behaviour. The control group cats (n = 5) were castrated without administration of the implant. Results Sexually dimorphic behaviours ceased within a mean ± SD of 13–58 days (23.30 ± 14.17) after implantation. DHT concentration decreased within 30 days. The mean duration of suppression was 26.5 ± 7.42 months and reactivation coincided with increased DHT values reaching preimplantation concentrations within 1 month. 17ß-oestradiol concentrations significantly correlated with DHT concentrations (P <0.01). Castration during suppression of sexual behaviour showed that the length of the long axes of the nuclei of Leydig cells, the diameter of seminiferous tubules and the height of the epithelium of the seminiferous tubules did not change until 3–6 months after implantation, whereas at 12 and 32 months the measured values were even lower than in the control group. In the present study, castration after reactivation showed that the length of long axes of the nuclei of Leydig cells and the diameter of seminiferous tubules approached the values of the control group between 4 and 6 months after reactivation. Conclusions and relevance A deslorelin implant (4.7 mg) suppresses sexually dimorphic behaviour in tom cats without any side effects and with full reversibility; however, duration of suppression is highly individual


Özet

Yayın ingilizcedir. İngilizce özet aşağıdadır.

Gene expression profiles of some cytokines, growth factors, receptors, and enzymes (GM-CSF, IFNg, MMP-2, IGF-II, EGF, TGF-b, IGF-IIR) during pregnancy in the cat uterus

Original Article Theriogenology, Volume dx.doi.org/10.1016/j.theriogenology.2015.10.001, Issue dx.doi.org/10.1016/j.theriogenology.2015.10.001, 2015, Pages 1-7

Abstract

Early pregnancy is one of the most critical periods of pregnancy, and many factors such as cytokines, enzymes, and members of the immune system have to cooperate in a balanced way. In the present study, the gene expression profiles of factors associated with pregnancy such as EGF, transforming growth factor beta, granulocyte-macrophage colonystimulating factor, interferon gamma, insulin-like growth factor 2, insulin-like growth factor 2 receptor, and matrix metalloproteinase 2 were analyzed in uterine tissues of female cats. The cats were assigned to five groups: G1 (embryo positive, n= 7; 7th day after mating), G2 (after implantation, n = 7; 20th day after mating), G3 (midgestation, n = 7; 24–25th day after mating), G4 (late gestation, n =7; 30–45th day after mating), G5 (oocyte group, n = 7; 7th day after estrus). Tissue samples from the uterus and placenta were collected after ovariohysterectomy. Relative messenger RNA levels were determined by real-time polymerase chain reaction. All the factors examined were detected in all tissue samples. In the course of pregnancy, significantly higher expression of EGF and matrix metalloproteinase 2 in G2 than in G1 was observed (P < 0.05). Insulin-like growth factor 2 expression was higher in all groups than in G1 (P < 0.05). Upregulation of EGF during implantation was detected. The expression of interferon gamma was significantly higher in G3 than in G1 (P < 0.05). Transforming growth factor beta and granulocytemacrophage colony-stimulating factor were constantly expressed in all groups. In conclusion, the expressions of these factors in feline uterine tissue at different stages of pregnancy might indicate that these factors play roles in the development of pregnancy such as trophoblast invasion, vascularization, implantation, and placentation.


Özet

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Suppression of Fertility in Pre-pubertal Dogs and Cats

Review Reprod Dom Anim, Volume 49, Issue 2, 2014, Pages 21-27

Abstract

Pre-pubertal gonadectomy in dogs and cats is still controver- sially discussed because some consequences cause health problems. Nevertheless, postponement of puberty, that is, prevention of an increase in sexual hormones and thereby prevention of their manifold effects, is of major importance, not only in controlling overpopulation but also to preserve the genetic base for future breeding stock and pets. Therefore, alternatives for surgical suppression of fertility in pre-pubertal animals were critically reviewed. As a promising alternative, the slow-release GnRH agonist deslorelin and other GnRH analogues have been investigated. In female dogs and cats, puberty could be significantly postponed without initial flare- up effect and without disturbance of body development. First trials to delay puberty in female and male cats by application of a 4.7-mg deslorelin implant 24 h after birth so far are promising. In female dogs, a previous investigation showed that when the implant was inserted at the age of 4 months, the initial flare-up effect was prevented. Body development was normal in the studies reviewed here, and with the 9.4-mg implant, puberty was significantly delayed until the age of 21 months or older. In one study, bitches either received a 4.7- or a 9.4-mg implant at the age of 4 months and the epiphyses were mostly closed before the time of first oestrus. Using a 4.7-mg deslorelin implant in pre-pubertal male dogs significantly postponed puberty, and age at puberty was > 2 years when a 9.4-mg implant was used. However, further investigations are required, especially concerning the effect of different GnRH agonist dosages and resorption rates on the duration of postponement of puberty as well as long-term effects in both dogs and cats.


Özet

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Currrent Teaching

  • 2019 Bahar

    OBSTETRICS AND GYNAECOLOGY I

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Teaching History

  • 2016 BAHAR

    OBSTETRICS AND GYNAECOLOGY I

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  • 2019 GÜZ

    ARTIFICIAL INSEMINATION AND ANDROLOGY

    Learning of reproduction

  • 2016 GÜZ

    OBSTETRICS AND GYNAECOLOGY II

  • 2016 GÜZ

    OBSTETRICS AND GYNAECOLOGY II

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  • 2017 BAHAR

    OBSTETRICS AND GYNAECOLOGY I

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  • 2018 BAHAR

    OBSTETRICS AND GYNAECOLOGY I

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  • 2017 GÜZ

    OBSTETRICS AND GYNAECOLOGY II

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  • 2018 GÜZ

    OBSTETRICS AND GYNAECOLOGY II

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  • 2019 GÜZ

    OBSTETRICS AND GYNAECOLOGY II

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  • 2017 GÜZ

    OBSTETRICS AND GYNAECOLOGY II

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  • 2018 GÜZ

    OBSTETRICS AND GYNAECOLOGY II

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