Selim ASLAN

Veterınary

Veterinary Medicine

Profesör Doktor

Biography

Englisch: Curriculum Vitae Name Prof.Dr. Selim ASLAN Official address Near East University Veterinary Faculty Clinic for Obstetrics and Gynaecology Nicosia-TRNC selim.aslan@neu.edu.tr Tel:+3926751000/3145-3150 Marital status married Nationality Turkey Place and Date of birth Turkey, 26.12.1956 Education/Degrees: 2000- :Professor : University of Ankara 1995- : Associate Professor 1987-199 : PhD (Veterinary University Vienna/Austria) and Research (Advisor: ProfDDr. Kurt Arbeiter) Professional Appointments: 1983-1984 Continuing Education at the clinic in Bad-Hersfeld (Germany) 1985-1987 Research Assistant (Faculty of Veterinary Medicin –Ankara) 1987-1992: PhD (Veterinary University Vienna/Austria) and Research 1992-1995: Ankara University Veterinary Faculty. Clinic of Obstetrics and Gynaecology: Dr. Assistant /Ass.Prof. (1993) 01.03.1997-31.08.97 University of Veterinary Medicine Vienna: Clinic of Obstetrics, Gynecology and Andrology (Visiting Professor), 1998-2011 Ankara University, Faculty of Veterinary Medicine, Prof. Dr. 1999: Presentation at the Symposium "Small Animal Reproduction" on the occasion of the 70th birthday of em. Prof. Dr. DDr. h. c. Kurt Arbeiter: “Termination the early pregnanch in the Bitch” 2000- Munich, Maximillian University, Veterinary Faculty (Prof. Stolla) DAAD Scholarship (Research: Blood flow in the corpus luteum in cattle) 2001: Invitation of the Association of Veterinarians for a lecture in Tirol . Reproduction and Neonatology Congress, Alpbach, Tirol. 2008: Hannover, Clinic for Cattle, School of Veterinary Medicine (Prof.Dr. H. Bollwein) DAAD scholarship (Research: Effects of induction of ovulation with GnRH and hCG on follicular and luteal blood flow in Holstein Friesian heifers) 2011-……. Senior Scientist , Project Collaboration : Turkey (with various faculties together) , Vienna, Switzerland Clinic of Obstetrics, Gyneacology/ Institute for Anatomy and Histology (Senior Scientist,Project Collaboration) 2013: Invitation of the University of Zurich (Institute of Reproductive and molecular histology and anatomy on): Lecture: Introduction abortion in the bitch: Selecting the right method (Project Preparation and Presentation) Research and Clinical Fellowships: 1995-1996: Research and Clinical Work at the Veterinary University Vienna; Lectures at the Vet Med Ankara 1989- until to day : Participation in the fertility - and sterility congress (Februartagung) in Giessen, Munich, Berlin, Hannover, Leipzig and Zurich Current research Luteal Blood Flow and Luteal Size in the Cow causes of poor fertility in high milk producing dairy cows Beneficial effects of Beta-carotene injections on the fertility of postpartum dairy cows Contraception in dogs and cats (Induction of abortion; Pregnancy termination) Immunology of pregnancy and parturition (Expression of genes in the canine uterus and embryo; Immunological aspects during early canine pregnancy; Expression of genes in the canine preimplantation uterus and embryo:implications for an active role of the embryo before and duringinvasion; Embryo–maternal interaction in early-pregnancy Heard Management in the Cow Scientific Cooperation: Akıllı Sürü ve Çiftlik Yönetim Karar destek Sistemi) (Smart Herd and Farm Management Decision Support System), Tübitak TEYDEB Project; 1501; Veterinary University of Vienna, Clinic for Obstetrics and Gynecology Oktober 1987 –1998 (Prof.DDr. K. Arbeiter); 2000- until today we have projects together (Prof.Dr. Sabine Shaefer-Somi) Clinic for Reproduction , Vetuisse-Faculty, University of Zurich, Switzerland (Prof.Dr. Heinrich Bollwein) 2000-until today we have projects together Justus-Liebig-Universität Giessen, Veterinary Medicine, Clinic of Obstetrics, Gynecology and Andrology; Germany (Prof.Dr. B. Hoffmann ) 2005-2011 Institute of Veterinary Anatomy, Vetsuisse-Faculty, University of Zurich, 8057 Zurich, Switzerland 2006- until today we have projects together (Prof.Dr. Mariusz Kowalewski ) Department of Large Animal Sciences, Section Veterinary Reproduction and Obstetrics, Denmark, 2014- (Ass.Prof.Dr. Sandra Goericke-Pesch) Grants / Funds / Promotions - Third party funds by Virbac Austria GmbH Research promotion for the investigation of repeated induction of abortion with the antiprogesteron Aglepristone, and for the use of the GnRH Analogue Deslorelin in prepubertal dogs (material expenses). - Grant of the Uni Ankara (research promotion; In different times) - Research promotion of the Vetmeduni Ankara (Expression and activity of matrixmetalloproteinases in the uterus of bitches after spontaneous and induced abortion; - Third party funds by Virbac Austria GmbH Research promotion for the investigation of repeated induction of abortion with the antiprogesteron Aglepristone, and for the use of the GnRH Analogue Deslorelin in prepubertal dogs (material expenses). Alvetra&Werfft AG, Austria : The change in luteal blood flow and luteal size after the beta carotene injections in early pregnant dairy cows Memberships Austrian Society of Veterinarians (ÖGT) European Society for Domestic Animal Reproduction (ESDAR) Society of Homöpaty (Honor President) Deutsch: LEBENSLAUF Persönliche Daten: Vorname: Selim Familienname: Aslan Akademischer Titel: Prof. Akademischer Grad: Dr. med. vet. Geburtsdatum: 26.12.1956 Geburtsort: Iskenderun, Türkei Arbeitsplatz: Near East University, Clinic for Obstetrics and Gynaecology Nicosia-TRNC-Mersin 10 selim.aslan@neu.tr z.Z. Wissenschaftliche Arbeit an der Veterinärmedizinischen (Senior Scientist): Universität Wien;Prof.Dr. Sabine Shaefer-Somi), Zurich (Prof.Dr. Mariusz Kowalewski; Anatomie und Hystologie) , Zürich (Prof.Dr. Heinrich Bollwein; Rinderklinik); Denemark (Ass.Prof.Sandra Goericke Pesch) Familienstand: verheiratet, 1 Kind Kontaktadresse: Elisen straße 6/4 A-1023 Wien Aufenthaltsstatus Österreich: unbefristete Aufenthalts- und Arbeitsgenehmigung Daten zur Ausbildung und Berufslaufbahn 13.6.1983: Abschluss des Studiums, Verleihung des Titels Diplomtierarzt 1983 - 984: Mitarbeit in einer Tierarztpraxis in Bad Hersfeld, Deutschland 1985 - 1987: Universitätsassistent an der Universität Ankara, Arbeit als wissenschaftlicher und klinischer Mitarbeiter am Institut für Geburtshilfe und Gynäkologie. Die Klinikarbeit erstreckte sich über alle Bereiche der Gynäkologie und Geburtshilfe. Eine Spezialisierung und Schwerpunktbildung erfolgte über die Puerperalphase des Rindes. Auch die an der Universität Ankara im Rahmen der fachtierärztlichen Ausbildung gehaltenen Vorträge bezogen sich auf dieses Schwerpunktthema (Anwendung des PGF2? bei der Endometritisbe-handlung im Puerperium des Rindes; Behandlungen der Ovarkrankheiten im Puerperium des Rindes). Zu den Aufgaben der Studentenbetreuung zählten das Abhalten von Übungen und Klinikvorträgen zu verschiedenen gynäkologischen Themen. 1987 - 1992: Doktoratsstudium, wissenschaftliche Forschung und klinische Arbeit an der Veterinärmedizinischen Universität Wien, Klinik für Geburtshilfe, Gynäkologie und Andrologie Hauptthemen der wissenschaftlichen Forschung waren: Puerperalkontrollen und deren Auswirkungen auf die Trächtigkeit des Rindes, Erkrankungen im Puerperium und Therapiemöglichkeiten beim Rind, Frühträchtigkeits- und Ovartätigkeitsuntersuchungen mittels Ultraschall und Anwendung von Hor-monen (GnRH, PGF2?, etc.) und Vitaminen (ß-Karotin, etc.) im Puerperium. Die Ergebnisse der Arbeiten wurden auf Vorträgen in Berlin, Gießen, Wels, München und Ankara vorgestellt. 25.6.1992: Promotion zum Dr. med. vet. an der Veterinärmedizinischen Universität Wien (Thema: Die Auswirkung verschiedener Behandlungen während der p.p.-Periode auf die Fruchtbarkeit von Kühen). 1992 - 1993: Wissenschaftliche Arbeiten, Doktorandenbetreuung und Unterrichtstätigkeit an der Universität Ankara, Institut für Geburtshilfe und Gynäkologie 22.10.1993: Erlangung des akademischen Titels Univ. Dozent. (Ankara) (Vorlesungen, Leitung der Klinikarbeit, Betreuung des Hochschulgutes, Bestandsbetreuung in verschiedenen Rinderbetrieben ) 1994 - 1997: Wissenschaftliche Arbeiten an der Veterinärmedizinischen Universität Wien, Klinik für Geburtshlife, Gynäkolgie und Andrologie Die Arbeiten umfassten weitere Untersuchungen der Frühträchtigkeit beim Rind (Gelbkörper- und Follikelmessungen, Feststellung von Hohlräumen des Gelbkörpers, Progesteron-, Vitamin E-, Folsäure-, B12-, Östrogenbestimmun-gen im Blut in verschiedenen Phasen der Frühträchtigkeit des Rindes). 1.3.1997 - Bestellung zum Gastprofessor an der Veterinärmedizinischen Universität 31.8.1997 Wien, Klinik für Geburtshilfe und Gynäkologie Lehrveranstaltung: "Frühembryonale Entwicklungsstörungen" 1999 Vortrag beim Symposium „Kleintierreproduktion“ anlässlich des 70. Geburts-tages von em. Prof. Dr. DDr. h. c. Kurt Arbeiter: „Abbruch der frühen Trächtigkeit bei der Hündin durch die kombinierte Anwendung eines Prostaglandins (Gabbrostim®) und eines Antiprolaktins (Galastop®).“ Symposium Kleintierreproduktion, 17.07.1999 Wien, Austria 17.10.2000 Ordentlicher Universitätsprofessor an der Universität Ankara 1989 - 2001 Wissenschaftliche Zusammenarbeit mit der Veterinärmedizinischen Universität Wien, zahlreiche Vorträge und Publikationen in Deutschland und Österreich (siehe Publikationsliste) 2000 DAAD-Stipendium für Deutschland (für 3 Monate) und Beenden der gemeinsam durchgeführten wissenschaftlichen Arbeit an der Tiermedizini-schen Fakultät der Ludwig Maximilians-Universität-München (Thema: Untersuchung der Veränderungen in der Durchblutung des Corpus luteum, der Follikel und der Lutealzysten mittels Farbdopplersonographie beim Rind). 2000 Homöopathie- und Phytotherapie in den Rinderbetrieben und Publikationen zu diesen Themenbereichen. Doktorandenseminare zu den Themen Homöopathie und Akupunktur 2001 Einladung der Tierärztekammer zu einemVortrag in Tirol Vergleichende Untersuchungen zur Behandlung der bovinen Endometritis mit intrauterinen Instillaten. Der Wiederkäuer im Alpenraum, Reproduktion und Neonatologie. Congress Centrum Alpbach. Tirol. Österreich., (2001) 2000 bis 2008 Durchführung zahlreicher Projekte gemeimsam mit A. Prof. Dr. Schäfer-Somi (Veterinärmedizinische Universität Wien) Schwerpunkte der Projekte waren folgende Themen: The Uterine and Placental Expression of Growth Factors, MMP 2,9 and MHC-I,II during Early Canine Pregnancy The Uterine and Placental Expression of MMP-2, -9, MHC-I,-II and Progesterone Receptors after Interruption of Early Canine Pregnancy with Aglepristone Immunological aspects during early canine pregnancy The expression of hormones, cytokines, T-cells, matrix metalloproteinases and major histocompatibility complex in maternal and foetal tissue, and the function of progesterone as a regulatory factor Expression of genes in the canine preimplantation uterus and embryo: implications for an active role of the embryo before and during invasion Expression of genes in the canine uterus and embryo Lymphocyte subsets in the pregnant canine uterus Durchführung zahlreicher Projekte mit Prof. Dr. Handler (Veterinärmedizini- sche Universität Wien; zur Zeit Professor an der LMU München) Schwerpunkte der Projekte waren folgende Themen: Frühgravidität und embryonale bzw. frühfetale Mortalität bei der Kuh – Gelb- körperdynamik, Progesteron-, Vitamin-E-, Vitamin-B12-, ?-Carotin-, und Folsäurekonzentrationen im peripheren Blut. Verbesserung der postpartalen Fertilität von Kühen durch Pulsatilla miniplex® Eignung der sonographischen Beurteilung von Ovardynamik und Uterusinvo- lution zur Fertilitätsprognose im Puerperium des Rindes. Wirksamkeit der intrauterinen Behandlung von puerperalen und post-puerpe- ralen Endometritiden mit Eucacomp® bzw. Lotagen® beim Rind 2000 - 2008 Beauftragung durch die Universitätskomission (YÖK) zur Bewertung der Publikationen und mündlichen Prüfung der Dozenturkandidaten als Mitglied der Prüfungskommission (Ankara) 2001 - 2008 Betreuung folgender Rinderbetriebe - Konya-Ereğli (Name des Betriebs; AKBEL): 1200 Kühe bzw. Kalbinnen, Kälber (Ausbildung der Tierärzte, Puerperalkontrolle, Östrussynchroni-sationen, Ultraschalluntersuchungen, prophylaktische Therapien, etc.). Im selben Betrieb getrennt gehaltene Schafe:1400 (Trächtigkeitsuntersuchun-gen, Östrussynchronisationen, Schwergeburt, Prolapsusus Uterie- bzw. Vaginae-Behandlungen, Behandlungen der metabolische Erkrankungen, Mastitistherapien und Haltungsmasnahmen, etc.) - Ankara-Elmadağ (Name des Betriebs; BESLER ENTEGRE): 110 Kühe bzw. Kalbinnen, Kälber - In der Umgebung von Ankara Untersuchungen in verschiedenen Rinderbetrieben (Betriebsgrößen zwischen 60 und 120 Kühe) und Behandlung von Schafen und Ziegen 2005 - 2008 Wissenschaftliche Zusammenarbeit mit Prof. Dr. B. Hoffmann (Veterinär- medizinische Fakultät, Klinik für Geburtshilfe, Gynäkologie und Andrologie, Justus-Liebig Universität Gießen) 2007 Zweiwöchiger wissenschaftlicher Aufenthalt an der Veterinärmedizinischen Universität Wien, Klinik für Geburtshilfe und Gynäkologie über das ERASMUS- Programm. Abhalten der Vorlesung „Endometritis beim Rind (Ursachen, Diagnostik, verschiedene Therapien und Prophylaxe) 2008 DAAD-Stipendium (Deutschland) für 2 Monate. Zusammenarbeit mit Prof. Dr. H. Bollwein (Thema: Untersuchungen über die Auswirkung von GnRH und hCG auf die follikuläre und luteale Durchblutung des Rindes). 2008-2011 Lehre, Dissertationen, Vorträge, Seminare, Forschung an der Veterinärmedizinische Fakültät Ankara. 2011-…… Senior Scientist (Projekte mit der Veterinärmedizinische Universität Wien; Klinik für Geburtshilfe und Gynäkologie Centre for Artificial Insemination and Embryo Transfer; Wissenschaftliche Arbeit mit A.Prof.Dr. Sabine Shäfer- Somi) Wietere Projekte mit den Fakültäten Zurich (Bollwein, Kowalewski), Berlin (Prof.Dr. Johennes Handler), Ankara, Samsun, Aydın und Kars, Burdur Mitgliedschaften und Aufgabenbereiche: ESDAR (The european society for domestic animals reproduction) Türkischer Verein für Buiatrik Türkische Gesellschaft für Geburtshilfe und Gynäkologie Kommisionsmitglied der Habilitationsprüfung Kommissionsmitglied für die Beurteilung der im Ausland studierenden Assistenten Leiter für wissenschaftliche Angelegenheiten President der Homöopathie-Verein Ankara Kooperationen: Wien Prof. DDR. h.c. Kurt Arbeiter (Klinik für Geburtshilfe, Gynäkologie und Andrologie) – 1987 – 1998 Prof. Dr. Jörg Aurich, A.Prof. Dr. Sabine-Schäfer-Somi, Prof. Dr. Johannes Handler (Klinik für Geburtshilfe, Gynäkologie und Andrologie) – 1998 bis heute A.Prof. Dr. I. Walter (Institut für Histologie und Embryologie) – 2000 bis heute Ass. Prof. Dr. M. Platzl (Institut für Immunologie) – 2006 bis heute München: Prof. Dr. Rudolf Stolla (Tiermedizinische Fakultät der Ludwig Maximilians- Universität-München) – 2000 - 2002 Hannover: Prof. Dr. Heinrich Bollwein (Klinik für Rinder, Stiftung Tierärztliche Hoch- schule Hannover) – 2000 bis heute Gießen: Prof. DDr. Bernd Hoffmann (Klinik für Geburtshilfe, Gynäkologie und Andro- logie, Justus-Liebig Universität Gießen) – 2005 bis heute Leipzig: Prof. Dr. A. Sobiraj (Tierärztliche Fakultät der Universität Leipzig) – ab 2008 Schweiz: Dr. Kowalewski (Veterinärmedizinische Fakultät der Universität Zürich); 2009-……….. Prof.Dr. Bollwein (Veterinärmedizinische Fakultät der Universität Zürich); 2012-…………….. Interessen: Computer (Vista, SPSS, Power Point, Exel Adobe Photoshop 7.0, u.a.m.) Statistische Auswertungsmodelle klassische Musik, Theater und Kino, Literatur Homöopathie, Akupunktur Türkçe: İlk, Orta ve Lise Öğrenimini Ankara’da yaptı. Daha sonra Almanya’da (Bremen) Almanca öğrendi ve Bremen’de başladığı işletme iktisat eğitimini bırakarak Veteriner Hekimlik eğitimini seçti. Uludağ Üniversitesi Veteriner Fakültesini 1983 yılında bitirdi. Frankfurt’a yakın Bad-Hersfeld kasabasında bir Veteriner Hekim Aile’nin yanında Asistan Veteriner Hekim olarak çalıştı. 1985 yılında Ankara Üniversitesi Veteriner Fakültesine Araştırma Görevlisi olarak başladı. 1987 yılında kendi yazığı bir projenin kabul edilmesi sonucu Avusturya Hükümetin’den aldığı bursla (ÖAAD) başta proje çalışması ve arkasından doktora ve klinik alanında (büyük, küçük hayvan) Avustuya’da Prof.DDr.K. Arbeiter ile birlikte çalıştı. Bu süreç içerisinde Münih, Giessen,Ulm ve Berlin’de Fertilite ve Sterilite alanında kongrelerde bildiri sundu. 1992 ve 2011 tarihlerinde her biri iki ay olmak üzere değişik çalışma ve yöntemleri görmek üzere Amerika’da bulundu. 1992 yılında doçent ve 2000 yılında Profesör oldu. Bu süreç içerisinde birçok kez birlikte çalışmak üzere Viyana Veteriner Fakültesine davet edildi ve bu davetler sonucunda Türkiye ve Avusturya arasında bilimsel işbiliği olanakları çerçevesinde birçok çalışma yapıldı. Almanya’nın birçok kentinde (Berlin, Münih, Giessen, Hannover, Leipzig) ve İsviçre, Avusturya, Slovenya, Belçika, Polonya, Macaristan, Almanya, Hollanda, İtalya…. gibi ülkelerde kendi ve asistanları ile birlikte birçok kongreye katıldı, ileri jinekolojik teknikler üzerine sunular yaptı. 1998 yılında Viyana Üniversitesinde misafir profesör olarak görev aldı. 1987 yılından başlayarak Viyana Veteriner Üniversitesi Araştırma ve Geliştirme Çiftliğinde Prof.DDr. K. Arbeiter’ın eşliğinde hem öğrenci eğitimi, araştırmalar ve sürüyönetim, idare gelişim ve sağlığı alanında çalıştı, daha o dönemden başlayarak ultrasonografik tanıyı gebelik, siklus tayini ve embryonik ölümlerde uyguladı. Daha sonra ki yıllarda renkli doppler tanı yöntemlerini Prf.Dr. Bollwein (halen Zürich Üniversitesi Veteriner Fakültesi, Sığır Kliniği Bölüm Başkanı'dır) ile birlikte pratiğe uyguladı. DAAD Bursu ile Münih ve Hannover’de renkli doppler ile corpus luteum kan akışkanlığı üzerinde çalışmalar yaptı. Halen Viyana Veteriner Üniversitesi Doğum , Jinekoloji, Androloji ve Suni Tohumlama , Zürich Üniversitesi Anatomi-Histoloji , Danimarka Doğum Kliniği ve ayrıca Sığır Kliniği ile ve Türkiye’de ki değişik Fakültelerle birlikte bilimsel çalışmalarını uluslararası projeler bazında ve Workshoplar tarzında sürdürmektedir . Ayrıca değişik ülkelerde ve Türkiye’de “Reprodüktif Sürü İdaresi” alanında genel sürü sağlığının sağlanması, fertilite parametrelerinin iyileştirilmesi, etki eden etmenlerin belirlenmesi ve önlemler alınarak sağlıklı sürü yetiştirilmesi alanında 1989 yılından bugüne kadar çalışmaktadır. Avusturya Veteriner Hekimler Odasının daveti ile “İneklerde Endometritis Tedavi Seçenekleri ve Yenilikler”, Prof.Dr. K. Arbeiter için düzenlenen kongrede “Köpeklerde Abort amacıyla Cabergolin kullanım ve Uygulmaları”, İsviçre’de davet üzerine “Kedi ve Köpekte güncel kontrasepsiyon yöntemleri” ve değişik davetlerde değişik ülkelerde bu konular üzerine konferanslar vermiştir. Almanya’da Prof.Hoffmann (Giessen), Prof.Dr.Leidl ve Stolla (Münih), Avusturya’da (Prof.Dr. K.Arbeiter, Prof.Dr. Schaefer-Somi, M.Drillich), İsviçre’de (Prof.Dr. H.Bollwein, Prof.Dr. Boos ve A.O. Prof.Dr. Kowalewski), Danimarka Kopenhagen (AO Prof.Dr. Sandra K. Georicke-Pesch ile çalıştı ve halen çalışmaktadır. Değişik ulusal ve impact factor bakımından Veteriner Doğum ve Jinekoloji Alanında en yüksek olan uluslararası dergilerde (Reproduction, Animal Reproduction Science, Theriogenology, Reprod Dom Anim) yayınları çıkmış ve halen yurtdışındaki ve Türkiye’de ki çalışma grubu ile birlikte yayın yapmaktadır. Ve bu dergilerin hepsinden “reviewer” olarak gelen yayınların değerlendirmesi için kendisine yayın gönderilmektedir. Birçoğu uluslararası olmak üzere 86 yayını vardır ve halen süren projelerden yeni yayınlar hazırlanmaktadır. Değişik ülkelerde katıldığı veya sunu yaptığı kongre sayısı elli’nin üzerindedir. Çalışmalar genellikle uygulamayı açıklayıcı reprodüktif immünoloji, reprodüktif moleküler biyoloji veya anne yavru interaksiyonu ve uterus yangıları, abortus…… üzerine yapılmakta ve sürekli bu alanda değişik ülkelerde bilgi alış verişi olmaktadır. Sığırlarda ise “Corpus luteum kan akışkanlığı, endometritislerde yeni tanı yöntemleri ve hormonların uygulamada kullanımı, ekotekstür, Akupunktur ve Corpus luteum kan akışkanlığı, puerperium ” gibi konular üzerine yapılmaktadır. Köpeklerde kontrasepsiyon (çiftleşmenin engellenmesi, erken dönemde istenmeyen gebeliklerin medikal yöntemlerle bitirilmesi), doğum sonrası dönem, gebelik dönem patolojileri ve meme tümörü gibi birçok alanda uluslar arası düzeyde yayınlanmış eserleri bulunmaktadır. Yayınlarına “PubMed).” bilimsel iletişim sitesinden ulaşmak mümkündür. Özel çalışma alanlarından biride alternatif tedavi metodlarıdır (Homöopathie ve Akupunktur) ve gerektiğinde tevdide bu yöntemlerini de kullanmaktadır. Alternatif tedavi teknikleri eğitimini Viyana Veteriner Üniversitesinde Prof.Dr.Kothbauer’den almıştır. Prof.Dr. Selim Aslan evli ve bir çocuk babasıdır. ESDAR (European Society for Domestic Animal Reproduction) üyesidir.

Work Experience

Todate 2013

Prof.Dr.

Near East University, Obstetrics and Gynaecology; veterinary Faculty
2011

Senior Scientist; Proje Koordinatörü

Veterinaer Universitaet Wien, Vetsuisse-Faculty University of Zurich, Viyana (Doğum) , Zürich (Anatomi-Histoloji, Moleküler Biyoloji, Sığır Kliniği)Kopenhagen (Büyük hayvan Kliniği)
2014 2011

Proje koordinatörü; Büyük Hayvan ve Küçük Hayvan Klinik Dersleri, Uygulamalar;

Veterinaermedizinische Universitaet Wien, Geburtshilfe, Gynaekologie und Andrologie
Todate 2008

Prof.Dr. DAAD Stipendium

Stiftung Tieraerztliche Fakultaet Hannover, Klinik für Geburtshilfe u. Gynaecology
2011 2008

Prof.Dr.

Ankara Üniversitesi, Doğum ve Jinekoloji
2008 2008

Prof.Dr. DAAD Araştırma Bursu

Ludwig Maximillan Universitaet-München, Doğum ve Jinekoloji
2011 2000

Prof.Dr.

Ankara Üniversitesi, Doğum ve Jinekoloji Ana Bilim Dalı
1992 1987

Vet. Hek. Asistan Viyana Veteriner Üniversitesi Çiftliğinde Reprodüktif Sürü İdaresi ve Hastalıkları

Veterinaermedizinizche Universitaet Wien, Geburtshilfe, Gynaekologie, Andrologie
1984 1983

Asistan Vet Hek Almanya Hessen- Bad-Hersfeld

Dr. vet. med. Heinze, Klinik, İneklerde Sürü idaresi ve Sağlığı (Herd-Management)

Education & Training

Ph.D. 1992

Doğum , Jinekoloji, Obtetrik, Androloji ve Suni Tohumlama

Veterinaer Universitaet Wien
Master...

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Bachelor1983

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Veteriner Fakültesi

Honors, Awards and Grants

Research Summary

Reprodüktif immünoloji ve moleküler biyoloji (köpek-kedi) Uterus yangı faktörleri (köpek-kedi) Anne ve yavru interaksiyonu (köpek-kedi) Abort ve tedavi amaçlı ilaç kullanımı (köpek-kedi) İneklerde post partum (doğum sonrası) dönem İneklerde sürü yönetimi ve sürü idaresi İneklerde jinekolojik görüntüleme yöntemlerinin kullanımı (ultrasonografi, renkli doppler, eko tekstür analizleri....) Neonatlar 2017 YILI YAYINLARI (devam eden) Morphological, histological and molecular investigations on canine uterine tissue after ovariectomy S Schäfer-Somi, K Deichsel, H Beceriklisoy, D Korkmaz, I Walter, S Aslan Theriogenology 102, 80-86 2017 Functional implications of the utero-placental relaxin (RLN) system in the dog throughout pregnancy and at term M Nowak, A Gram, A Boos, S Aslan, SS Ay, F Önyay, MP Kowalewski Reproduction 154 (4), 415-431 2017 Expression of GnRH receptor in the canine corpus luteum, and luteal function following deslorelin acetate-induced puberty delay D Kaya, A Gram, MP Kowalewski, S Schäfer-Somi, M Kuru, A Boos, ... Reproduction in Domestic Animals 2017 Early pregnancy diagnosis in dairy cows by ultrasound and determination of bovine-pregnancy-associated glycoproteins, bovine pregnancy specific protein B and progesterone O Ergene, I Darbaz, S Sayiner, S Aslan REPRODUCTION IN DOMESTIC ANIMALS 52, 83-83 2017 Uterine responses to early pre-attachment embryos in the domestic dog and comparisons with other domestic animal species FR Graubner, A Gram, E Kautz, S Bauersachs, S Aslan, AR Agaoglu, ... Biology of Reproduction 97 (2), 197-216 2017 Kisspeptin-10 and the G protein-coupled receptor 54 are differentially expressed in the canine pregnant uterus and trophoblast cells S Schäfer-Somi, SS Ay, D Kaya, M Sözmen, HB Beceriklisoy, AR Ağaoğlu, ... Reproduction in Domestic Animals 52 (S2), 123-129 1 2017 Effect of deslorelin on testicular function, serum dihydrotestosterone and oestradiol concentrations during and after suppression of sexual activity in tom cats N Gültiken, S Aslan, SS Ay, MY Gülbahar, J Thuróczy, E Koldaş, D Kaya, ... Journal of feline medicine and surgery 19 (2), 123-131 1 2017 The Assessment of Diagnostic and Ultrasonographic Findings in a Bitch with True Vaginal Prolapse I Darbaz, O Ergene, E Canooglu, C Gultekin, S Aslan Kafkas Üniversitesi Veteriner Fakültesi Dergisi 23 (5), 843-846 2017 Koyun ve Keçilerde Metabolik Problemler ve Reprodüksiyona Etkileri S ASLAN, İ DARBAZ, O ERGENE Turkiye Klinikleri Journal of Veterinary Sciences-Obstetrics and Gynecology … 2017 Ovarian Tumour in a Bitch: Diagnosis, Surgery and Recovery I Darbaz, O Ergene, G Sonmez, S Aslan Kafkas Üniversitesi Veteriner Fakültesi Dergisi 23 (5), 839-842 2017 Pregnancy Markers in Serum of Bitches S Schäfer-SOMI, S ASLAN Turkiye Klinikleri Journal of Veterinary Sciences-Obstetrics and Gynecology … 2017 Association of luteal blood flow with follicular size, serum estrogen and progesterone concentrations, and the inducibility of luteolysis by PGF 2? in dairy cows S Kaya, C Kaçar, B Polat, A Çolak, D Kaya, İS Gürcan, H Bollwein, ... Theriogenology 87, 167-172 2 201

Interests

Research Projects

Maturation of canine feto-maternal axis. Role of utero/placental prostaglandins in the induction of parturition

investigate the effects of the different timepoints of Alizine application on the utero/placental prostaglandin-synthesis, luteal steroidogenesis and luteal as well as uteroplacental hormonal/receptor status

Background: The focus of our recent studies (Kowalewski et al., 2009, 2010, 2011a,b) was directed towards the cellular- and molecular mechanisms leading to the onset of parturition in the dog. In order to gain some more information about the molecular and endocrine events governing this process experiments were performed using the competitive progesterone receptor blocker - Alizine (Virbac). We observed similar changes in the utero/placental prostaglandins system during normal and Alizine-induced parturition/abortion. Our main findings pointed towards the progesterone-receptor mediated alterations in the feto-maternal communication, between the maternal decidual cells (the only cells in the canine placenta expressing progesterone receptor) and the fetal trophoblast cells, as the main trigger for the prepartal PGF2? output in the dog. But „similar“ does not mean „identical“. From the clinical point of view it is known that the uterine contractions after the application of Alizine seem to be less pronounced than during the normal parturition. This becomes more obvious when Alizine is being applied in the mid- and late- pregnancy, where fetal resorption is not anymore possible and the application of Alizine must result in an abortion. The action of Alizine beyond 45th day of pregnancy is diminished. From the clinical point of view-administration of this compound as monothepeutic at 3rd timester of pregnancy may not induce the foetal expulsion. Therefore, clinicians have developed several protocols comprising e.g. the usage of oxytocin or PGF2? in order to improve the process of parturition. The effects of Alizine on the cessation of the luteal steroidogenic function (= decrease of peripheral progesterone levels) and uterine contractions and finally on the outcome of parturition seem to depend upon the timepoint of Alizine application during the course of pregnancy Goal: The main goal of the ongoing project is: - to investigate the effects of the different timepoints of Alizine application (early-, mid-, late- pregnancy) on the utero/placental prostaglandin-synthesis, luteal steroidogenesis and luteal as well as uteroplacental hormonal/receptor status. Significance of the planned work: With this project we expect to provide clinically active colleagues with new information that could be helpful in optimizing and developing of new treatment protocols. From the scientific (basic sciences) point of view we expect a significant contribution to the understanding of endocrine mechanisms regulating canine reproduction.
The downregulated dog and recrudescence of spermatogenesis.

The aim of the study is to characterise downregulation of germinative and endocrine testicular function following treatment with a 4.7 mg deslorelin implant in dogs and recrudescence after abolition of downregulation by implant removal.

(1) University of Copenhagen (UCPH), Department of Large Animal Science, Faculty of Health and Science, Copenhagen University, Denmark, with registered office at Copenhagen, registered under number cvr. 29 97 98 12, represented by Mr Hans Henrik Dietz, Department Head (the “Principal Investigator”). (2) University of Ondokuz Mayıs (UOM), Faculty of Veterinary Medicine, Department of Clinical Sciences, 55200, Samsun, Turkey, represented by Prof. Murat Findik (the “Sub-Contractor”). (3) Prof. Selim Aslan (SA), Nera East University, Veterinary Faculty, Obstetrics and Gynecology, Nicosia-TRNC, CYPRUS, will serve as a coordinator of the study – responsible for coordination of the study at and with UOM and communication with Assoc. Prof. Dr. Sandra Goericke-Pesch from UCPH (the “coordinator”) Project description: The downregulated dog and recrudescence of spermatogenesis The aim of the study is to characterise downregulation of germinative and endocrine testicular function following treatment with a 4.7 mg deslorelin implant in dogs and recrudescence after abolition of downregulation by implant removal. Furthermore, full reversibility of all treatment-induced effects should be confirmed by hemi-castration of 4 dogs at the time of downregulation and weekly follow-ups until return to pre-treatment semen parameters followed by removal of the second testis. Experimental design: All dogs will be submitted to a clinical and andrological examination including measurement of testicular size (length, width, height) and assessment of semen quality. Only healthy dogs without andrological deviations and semen parameters within the normal range as defined by Günzel-Apel et al. (1994) Riesenbeck et al. (2001) and Pesch et al. (2007) (see below) will be included. Day of examination and inclusion into study will be defined as day 0. A blood sample will be collected for hormone measurements (testosterone (T), estradiol-17ß (E2), luteinizing hormone (LH), follicle stimulating hormone (FSH) concentrations etc.). The dogs will be randomly assigned to the following two treatment groups: Group 1 (n=5): control; castration after clinical examination and preservation of testicular and epididymal tissue for further examinations according to the protocol below. Group 2 (n=45): treatment with a slow release GnRH-agonist implant (Suprelorin®, 4.7 mg deslorelin) subcutaneously at the paraumbilical region on day 0, blood sampling and andrological examination including measurement of testicular size on days 28, 56 and 84 (= weeks +4, +8, +12), implant removal under local anaesthesia after 5 months (week 0), surgical castration of four to five dogs each at weeks 0, 1, 2, 3, 4, 5, 6, 8, 10. Following implant removal, weekly blood sampling and andrological examination until castration. On the day of castration, blood sampling, testicular measurements before castration and preservation of testicular and epididymal tissue for further examinations (figure 1). Except for four dogs in week 0, both testes will be removed at the time of castrations. In week 0, hemicastration will be performed in four dogs (figure 2). Weekly semen collections until return to normal (before-treatment) semen parameters (week x) should be performed followed by surgical removal of the second testis (week x+1) and preservation of testicular and epididymal tissue for further examinations.

Publications

Abstract

Özet

Yayınlar 2017 Morphological, histological and molecular investigations on canine uterine tissue after ovariectomy S Schäfer-Somi, K Deichsel, H Beceriklisoy, D Korkmaz, I Walter, S Aslan Theriogenology 102, 80-86 2017 Functional implications of the utero-placental relaxin (RLN) system in the dog throughout pregnancy and at term M Nowak, A Gram, A Boos, S Aslan, SS Ay, F Önyay, MP Kowalewski Reproduction 154 (4), 415-431 2017 Expression of GnRH receptor in the canine corpus luteum, and luteal function following deslorelin acetate-induced puberty delay D Kaya, A Gram, MP Kowalewski, S Schäfer-Somi, M Kuru, A Boos, ... Reproduction in Domestic Animals 2017 Early pregnancy diagnosis in dairy cows by ultrasound and determination of bovine-pregnancy-associated glycoproteins, bovine pregnancy specific protein B and progesterone O Ergene, I Darbaz, S Sayiner, S Aslan REPRODUCTION IN DOMESTIC ANIMALS 52, 83-83 2017 Uterine responses to early pre-attachment embryos in the domestic dog and comparisons with other domestic animal species FR Graubner, A Gram, E Kautz, S Bauersachs, S Aslan, AR Agaoglu, ... Biology of Reproduction 97 (2), 197-216 2017 Kisspeptin-10 and the G protein-coupled receptor 54 are differentially expressed in the canine pregnant uterus and trophoblast cells S Schäfer-Somi, SS Ay, D Kaya, M Sözmen, HB Beceriklisoy, AR Ağaoğlu, ... Reproduction in Domestic Animals 52 (S2), 123-129 1 2017 Effect of deslorelin on testicular function, serum dihydrotestosterone and oestradiol concentrations during and after suppression of sexual activity in tom cats N Gültiken, S Aslan, SS Ay, MY Gülbahar, J Thuróczy, E Koldaş, D Kaya, ... Journal of feline medicine and surgery 19 (2), 123-131 1 2017 The Assessment of Diagnostic and Ultrasonographic Findings in a Bitch with True Vaginal Prolapse I Darbaz, O Ergene, E Canooglu, C Gultekin, S Aslan Kafkas Üniversitesi Veteriner Fakültesi Dergisi 23 (5), 843-846 2017 Koyun ve Keçilerde Metabolik Problemler ve Reprodüksiyona Etkileri S ASLAN, İ DARBAZ, O ERGENE Turkiye Klinikleri Journal of Veterinary Sciences-Obstetrics and Gynecology … 2017 Ovarian Tumour in a Bitch: Diagnosis, Surgery and Recovery I Darbaz, O Ergene, G Sonmez, S Aslan Kafkas Üniversitesi Veteriner Fakültesi Dergisi 23 (5), 839-842 2017 Pregnancy Markers in Serum of Bitches S Schäfer-SOMI, S ASLAN Turkiye Klinikleri Journal of Veterinary Sciences-Obstetrics and Gynecology … 2017 Association of luteal blood flow with follicular size, serum estrogen and progesterone concentrations, and the inducibility of luteolysis by PGF 2? in dairy cows S Kaya, C Kaçar, B Polat, A Çolak, D Kaya, İS Gürcan, H Bollwein, ... Theriogenology 87, 167-172 2 2017

Comparison of various diagnostic techniques used for examination of ovaries in cows.

Original Article Deutsche Tierärztliche Wochenschrift, Volume *, Issue -, 2000, Pages -

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Özet

Use of exfoliative cytology for diagnosis of transmissible venereal tumour and controlling the recovery period in the bitch.

Original Article DTW. Deutsche tierarztliche Wochenschrift, Volume 107, Issue 5, 2000, Pages 175-180

Tarantula cubensis extract changes the degree of apoptosis and mitosis in canine mammary adenocarcinomas.

Original Article Journal of veterinary science, Volume *, Issue -, 2014, Pages -

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Clinical evaluation of different applications of misoprostol and aglepristone for induction of abortion in bitches

Original Article Theriogenology, Volume 81, Issue 7, 2014, Pages 947-951

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Gene expression profiles of some cytokines, growth factors, receptors, and enzymes (GM-CSF, IFN?, MMP-2, IGF-II, EGF, TGF-ß, IGF-IIR) during pregnancy in the cat uterus

Original Article Theriogenology, Volume *, Issue -, 2015, Pages -

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Effect of deslorelin on testicular function, serum dihydrotestosterone and oestradiol concentrations during and after suppression of sexual activity in tom cats

Original Article Journal of feline medicine and surgery, Volume *, Issue -, 2015, Pages -

Abstract

Özet

GnRH and its receptor (GnRH-R) are expressed in the canine placenta and uterus

Original Article Theriogenology, Volume 84, Issue 9, 2015, Pages 1482-1489

Abstract

In reproductive tissues, GnRH participates in the regulation of cell growth and proliferation by direct binding to the GnRH-R, which is essential for embryo implantation. However, there is no study on the expression and cellular localization of GnRH and GnRH-R in the canine uterus and placenta. Therefore, bitches were ovariohysterectomized 10 to 12 days after mating (vaginal cytology and progesterone measurement), the uteri were flushed, and if embryos were detectable, bitches were allocated to the embryo positive group (E-pos.; preimplantation, n = 5). Other bitches were operated at later stages and, dependent on the gestational age, either allotted to the post-implantation group (Day 18–25 after mating, n = 9), or the mid-gestation group (Day 30–40 after mating, n = 3). Dogs negative in embryo flushing served as controls (E-neg.; controls, n = 5). Samples of the entire uterine wall were taken from the middle of the horn in E-neg. and E-pos. groups, and from placental and interplacental uterine sites in post-implantation and mid-gestation groups. GnRH-R expression was localized at the mRNA and protein levels by immunohistochemistry and in situ hybridization. The expression of GnRH and GnRH-R mRNA was assessed by semiquantitative polymerase chain reaction. Additionally, both GnRH and GnRH-R mRNA were expressed in all tissues examined until mid-gestation. Relative expression of GnRH was higher than that of GnRH-R (P < 0.05). During the post-implantation stage, GnRH-R expression was significantly higher in uteroplacental than in interplacental tissues. In the uterus, GnRH-R stained strongly in the surface and glandular epithelial cells, and seemed to be weaker in myometrium and stroma. Placental signals were predominantly localized in fetal trophoblast cells and to a lesser extent in maternal decidual cells. These findings suggest a local regulatory function of GnRH during early canine pregnancy.

Özet

Yayın ingilizcedir.

GnRH and its receptor (GnRH-R) are expressed in the canine placenta and uterus

Original Article Theriogenology, Volume 84, Issue -, 2015, Pages 1482-1489

Abstract

Abstract

Hypoxia-inducible factors (HIFs) and vascular endothelial growth factor (VEGF) have critical roles during the development of the fetomaternal unit. The HIFs regulate placentation and vascularization by stimulation of VEGF gene expression. This study aimed to investigate the expression profiles of HIF gene family and VEGF in the cat uterus during pregnancy. Tissue samples of the whole uterine wall were collected after ovariohysterectomy and allocated to the following groups: embryo positive (group 1 [G1], n = 7, 7 days after mating), early pregnancy (group 2 [G2], n = 7, 20 days after mating), mid-pregnancy (group 3 [G3], n = 7, 24 days after mating), late pregnancy (group 4 [G4], n = 7, 30–45 days after mating), and oocyte positive groups (group 5 [G5], n ¼ 7, 7 days after induction of ovulation with GnRH analog). Relative mRNA levels were determined by real-time polymerase chain reaction. As housekeeping gene, glyceraldehyde-3-phosphate dehydrogenase was used. The relative gene expression of HIF1A in G5 was found to be significantly higher than that of other groups (G1, G2, G3, and G4) (P < 0.05). In addition, the expression of HIF2A in G5 was higher than that of G1 and HIF2A gene expression at placentation sites of G4 was higher than in G1, G2, and G3 (P < 0.05). Immunohistochemistry indicated that HIF1A, HIF2A, and VEGF expressions were observed in different cell types of uterine and placental tissues in late pregnancy and oocyte groups. The expression of HIF3A did not change significantly in any group investigated. These observations suggest that HIFs and VEGF may play a role in the establishment and development of pregnancy

Review ingilizcedir.

Teaching

Currrent Teaching

2019 YAZ

OBSTETRICS AND GYNAECOLOGY I

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2019 YAZ

OBSTETRICS AND GYNAECOLOGY II

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Teaching History

2016 BAHAR

OBSTETRICS AND GYNAECOLOGY I

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2017 BAHAR

OBSTETRICS AND GYNAECOLOGY I

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2018 BAHAR

OBSTETRICS AND GYNAECOLOGY I

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2019 BAHAR

OBSTETRICS AND GYNAECOLOGY I

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2017 GÜZ

OBSTETRICS AND GYNAECOLOGY II

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2018 GÜZ

OBSTETRICS AND GYNAECOLOGY II

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2019 GÜZ

OBSTETRICS AND GYNAECOLOGY II

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2016 GÜZ

OBSTETRICS AND GYNAECOLOGY II
2016 GÜZ

OBSTETRICS AND GYNAECOLOGY II

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2017 GÜZ

OBSTETRICS AND GYNAECOLOGY II

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2018 GÜZ

OBSTETRICS AND GYNAECOLOGY II

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2019 GÜZ

ARTIFICIAL INSEMINATION AND ANDROLOGY

Learning of reproduction

Gallery

Contact & Meet Me

1999: Presentation at the Symposium "Small Animal Reproduction" on the occasion of the 70th birthday of em. Prof. Dr. DDr. h. c. Kurt Arbeiter: “Termination the early pregnanch in the Bitch” 2000- Munich, Maximillian University, Veterinary Faculty (Prof. Stolla) DAAD Scholarship (Research: Blood flow in the corpus luteum in cattle) 2001: Invitation of the Association of Veterinarians for a lecture in Tirol . Reproduction and Neonatology Congress, Alpbach, Tirol. 2008: Hannover, Clinic for Cattle, School of Veterinary Medicine (Prof.Dr. H. Bollwein) DAAD scholarship (Research: Effects of induction of ovulation with GnRH and hCG on follicular and luteal blood flow in Holstein Friesian heifers) 2011-……. Senior Scientist , Project Collaboration : Turkey (with various faculties together) , Vienna, Switzerland Clinic of Obstetrics, Gyneacology/ Institute for Anatomy and Histology 2013-: Invitation of the University of Zurich (Institute of Reproductive and molecular histology and anatomy on): Lecture: Introduction abortion in the bitch: Selecti

Selim ASLAN

Veterınary

Veterınary

Veterinary Medicine

Profesör Doktor

Biography

Work Experience

Prof.Dr.

Senior Scientist; Proje Koordinatörü

Proje koordinatörü; Büyük Hayvan ve Küçük Hayvan Klinik Dersleri, Uygulamalar;

Prof.Dr. DAAD Stipendium

Prof.Dr.

Prof.Dr. DAAD Araştırma Bursu

Prof.Dr.

Vet. Hek. Asistan Viyana Veteriner Üniversitesi Çiftliğinde Reprodüktif Sürü İdaresi ve Hastalıkları

Asistan Vet Hek Almanya Hessen- Bad-Hersfeld

Education & Training

Honors, Awards and Grants

Research Summary

Interests

Research Projects

Maturation of canine feto-maternal axis. Role of utero/placental prostaglandins in the induction of parturition

The downregulated dog and recrudescence of spermatogenesis.

Publications

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http://onlinelibrary.wiley.com/doi/10.1111/j.1439-0531.2006.00838.x/full

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http://www.sciencedirect.com/science/article/pii/S0378432008005010

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http://www.reproduction-online.org/content/139/3/655.short

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http://europepmc.org/abstract/med/10887668

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http://www.sciencedirect.com/science/article/pii/S0378432010003805

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http://rbej.biomedcentral.com/articles/10.1186/1477-7827-9-109

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http://onlinelibrary.wiley.com/doi/10.1111/j.1439-0531.2007.00966.x/full

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http://www.sciencedirect.com/science/article/pii/S0093691X10005583

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http://eski.teb.org.tr/akademi/journal/?p=content&vol=5&no=1

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http://www.sciencedirect.com/science/article/pii/S0093691X07003834

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http://www.sciencedirect.com/science/article/pii/S0093691X03003510

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http://www.sciencedirect.com/science/article/pii/S0378432011000583

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http://journals.tubitak.gov.tr/veterinary/abstract.htm?id=3118

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http://onlinelibrary.wiley.com/doi/10.1111/j.1439-0531.2009.01443.x/full

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http://scholar.google.com/scholar?cluster=18138338297289057260&hl=en&oi=scholarr

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http://onlinelibrary.wiley.com/doi/10.1111/j.1439-0531.2012.02019.x/full

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http://scholar.google.com/scholar?cluster=10117852828477023464&hl=en&oi=scholarr

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http://scholar.google.com/scholar?cluster=7800005962841184497&hl=en&oi=scholarr

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http://www.sciencedirect.com/science/article/pii/S0093691X13001258