Farmakoloji Anabilim Dalı Başkanı
Yakın Doğu Üniversitesi, Eczacılık Fakültesi
Biography
Ankara Üniversitesi Eczacılık Fakültesinden mezun olduktan sonra, yine aynı fakültenin Farmakoloji Anabilim Dalında 1976 yılında, akademik ve mesleki hayatına başladı. 1982 yılında aynı departmanda doktorasını tamamladı. 1984 yılında öğretim görevlisi kadrosuyla Gazi Üniversitesi Eczacılık Fakültesi Farmakoloji Anabilim Dalına geçti. Aynı fakültede 1985 yılında Yardımcı Doçent, 1987 yılında Doçent ve 1992 yılında Profesörlüğe yükseltildi. 1994-1995 yılları arasında bu fakültenin Dekan yardımcılığı görevini sürdürdü. 2002-2016 yılları arasında Farmakoloji Anabilim Dalı Başkanlığı, 2011-2016 yılları arasında da Meslek Bilimleri Bölüm Başkanlığını sürdürdü. Bu fakültenin akademik ve idari çeşitli kurullarında yer aldı. 1984-1990 yılları arasında Türk Eczacıları Birliği Merkez Heyeti Genel Sekreterliği yaptı. Aynı yıllardan başlayarak Devlet Planlama Teşkilatı, ve Sağlık Bakanlığı'nın çeşitli komisyonlarında uzun yıllar görev yaptı. 2013 yılında Türk Eczacıları Birliği Eczacılık Akademisi Hizmet Ödülünü aldı. Bu akademik kurumlarda araştırma makalesi, ulusal ve uluslararası kongre tebliğleri, derlem makaleler ve kitaplar olmak üzere dört yüzden fazla yayın sahibi oldu. 2016 yılında Türk Farmakoloji Derneği meslekte 40. yıl Hizmet Ödülünü aldı ve erken emekli oldu. Şubat 2016 tarihinden bu yana Yakın Doğu Üniversitesi Eczacılık Fakültesine tam zamanlı olarak çalışmaktadır. Halen aynı fakültede öğretim üyeliği ve Farmakoloji Anabilim Dalı Başkanlığı görevlerini sürdürmektedir.
Work Experience
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Todate 2016
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2016 2011
Meslek Bilimleri Bölüm Başkanı
Gazi Üniversitesi Eczacılık Fakültesi, Meslek Bilimleri Bölümü
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2016 2002
Farmakoloji Anabilim Dalı Başkanı,
Gazi Üniversitesi Eczacılık Fakültesi, Farmakoloji Anabilim Dalı
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1995 1994
Dekan Yardımcısı
Gazi Üniversitesi Eczacılık Fakültesi, Gazi Üniversitesi Eczacılık Fakültesi
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2016 1992
Prof. Dr.
Gazi Üniversitesi Eczacılık fakültesi, Farmakoloji Anabilim Dalı,
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1992 1987
Doç. Dr.
Gazi Üniversitesi Eczacılık fakültesi, Farmakoloji Anabilim Dalı
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1987 1985
Yrd. Doç. Dr.
Gazi Üniversitesi Eczacılık Fakültesi, Farmakoloji Anabilim Dalı
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1985 1984
Dr. Öğretim Görevlisi
Gazi Üniversitesi Eczacılık Fakültesi, Farmakoloji Anabilim Dalı
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1984 1982
Doktor Asistan
Ankara Üniversitesi Eczacılık Fakültesi, Farmakoloji Anabilim Dalı, Ankara
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1982 1976
Asistan,
Ankara Üniversitesi Eczacılık Fakültesi, , Farmakoloji Anabilim Dalı, Ankara
Education & Training
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Ph.D. 1982
Farmakoloji
Ankara Üniversitesi
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Master...
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Bachelor1975
Eczacılık
Ankara Üniversitesi
Honors, Awards and Grants
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2013Türk Eczacıları Birliği Eczacılık Akademisi Hizmet Ödülü
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2016Türk Farmakoloji derneği Meslekte 40 Yıl Hizmet Ödülü
Research Summary
Kronobiyoloji, Kronofarmakoloji, Kronoterapi, kardiyovasküler ve Otakoid Farmakoloji, Ağrı Farmakolojisi
Interests
Research Projects
Publications
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Abstract
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Özet
ABACIOĞLU N, BEDİZ A, ÇAKICI İ, TUNÇTAN B, KANZIK İ (1993) Antinociceptive effects of H1 of H2-antihistaminics in mice General Pharmacology, 24(5), 1173-1176
Abstract
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Özet
HODOĞLUGİL U, AKTUNA-KESKİL Z, GÖRGÜN CZ, ULUOĞLU C, ABACIOĞLU N, ZENGİL H (1999) Effect of time on endothelium-dependent relaxations in mice and rat thoracic aortas Biol Rhythm Res 30(4), 434-444
Abstract
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Özet
MEMİŞ A, UZUN Ö, ULUSOY E, ABACIOĞLU N, KANZIK İ (1994) Ceftriaxon for the therapy of chronic bacterial prostatitis Therapy 49: 49
Abstract
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Özet
SUNAL R, KANZIK İ, ABACIOĞLU N (1985) Hypothermic effect of cimetidine in rats Turkish J Pharmacol Clin Res 3(1,2), 83-86
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Özet
ABACIOĞLU N, TUNÇTAN B, AKBULUT E, ÇAKICI İ (2000) Participation of the components of L-arginine/nitric oxide/cGMP cascade by p-benzoquinone-induced nociceptive processes in the mouse Life Sciences 67(10): 1127-1137
Abstract
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Özet
ALTINKURT O, ABACIOĞLU N Non-competitive inhibition of angiotensin II and PGE2 on guinea-pig ileum with streptomycine, vit K3 and rutin Arzneim-Forsch Drug Res 30 (1) 4, 610-613 (1980)
Abstract
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Özet
HENGİRMAN, S, UZUN, Ö, TERZİ, C, CETE, M, ABACIOĞLU, N, KANZIK, İ (1992) Comparison of serum, gallbladder wall and bile concentrations of cefazolin and cefoxitin in elective biliary surgery J Fac Pharm Gazi 9 (1), 19-26
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Özet
GÜNEY HZ, ULUOĞLU C, HODOĞLUGİL U, GÖRGÜN CZ, YAMANOĞLU T, ABACIOĞLU N, ZENGİL H (1999) Biological-time dependent differences in effect of verapamil on rat aorta and influence of endothelium Chronobiol Int, 16(6), 779-787
Abstract
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Özet
GÖRGÜN CZ, HODOĞLUGİL U, KESKİL RZ, ERCAN ZS, ABACIOĞLU N, ZENGİL H (1998) In vitro evidence on the tissue susceptibility rhythm I Temporal variations in the effect of potassium chloride and phenylephrine in rat aorta Chronobiol Int 15(2), 39-48
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Özet
ALTIPARMAK H, ÇAKICI İ, KANZIK İ, ABACIOĞLU N (1992) Implementation and validation of probit transformation in linearizing dose-response curves and statistical analysis J Fac Pharm Gazi 9(2): 107-113
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Özet
TUNÇTAN, B, ULUDAĞ, O, ALTUĞ, S, ABACIOĞLU, N (1998) Effects of nitric oxide synthase inhibition in lipopolysaccharide-induced sepsis in mice Pharmacological Research, Vol 38,(5),405-411
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Özet
ERDEMOGLU N, TURAN NN, AKKOL EK, SENER B, ABACIOGLU N (2009) Estimation of anti-inflammatory, antinociceptive and antioxidant activities of Arctium minus (Hill) Bernh. ssp. minus. J Ethnopharmacol. 21;121(2):318-23.
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Özet
ÇAKICl İ, ULUĞ HY, İNCİ S, TUNÇTAN B, ABACIOĞLU N, KANZIK, İ, ŞENER, B (1997) Antinociceptive effect of some Amaryllidaceae plants J Pharm Pharmacol 49, 828-830
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Özet
ALAGÖL H, DİNÇ S, BASGUT B, ABACIOĞLU N (2007) Temporal variation in the recovery from impairment in adriamycin-induced wound healing in rats Journal of Circadian Rhythms 5:6, doi:10. 1186/1740-3391-5-6
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Özet
ÇAKICI İ, ZENGİL H, ABACIOĞLU N, KANZIK İ (1989) The temperature dependent specific desensitization in the rat anococcygeus muscle to angiotensin II Pharmacology, 39(2) : 115-120
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Özet
ALTINKURT O, ABACIOĞLU N (1984) The possible decompensation process depend on plasma angiotensin degredation in electroshock AEOB 6: 1, 36-45 (Turkish / English Abstract)
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Özet
TUNÇTAN B, ALTUĞ S, ULUDAĞ O, ABACIOĞLU N (2000) Effects of econazole on receptor-operated and depolarization-induced contractions in rat isolated aorta Life Sciences 67: 2393-2401
Abstract
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Özet
KANZIK İ, DEMİRYÜREK T, ZENGİL H, ABACIOĞLU N, DÖRTLEMEZ H (1988) Effects of thromboxane synthetase inhibitör (UK 38 485) and thromboxane receptor antagonist (iCI 185, 282) on digoxin-induced arrhythmias in anaesthetised guinea-pigs Clin Exp Pharmacol Physiol 15, 925-937
Abstract
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Özet
TUNÇTAN B, ALTUĞ S, ULUDAĞ O, ABACIOĞLU N (2000) Time-dependent variation in serum nitrite, 6-k-PGF1? and TxB2 levels induced by lipopolysaccharide in mice Biological Rhythm Research 31(49: 514 )
Abstract
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Özet
AKAR F, ARK M, UYDEŞ BS, SOYSAL ME, SARAÇOĞLU F, ABACIOĞLU N, VOORDE J Van De, KANZIK İ (1994) Nitric oxide production by human umbilical vessels in severe preeclampsia Journal of Hypertension 12, 1235-1241
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Özet
ÇAKICl İ, MATARACI N, ERSOY S, TUNÇTAN B, ABACIOĞLU N, KANZIK İ (1995) Effects of PAF antagonists WEB 2086 and BN 50730 on digoxin-induced arrhythmias Pharmacol Toxicol 76(6): 343-347
Abstract
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Özet
HODOĞLUGİL U, ULUOĞLU C, GÜNEY HZ, GÖRGÜN CZ, ERCAN ZS, ABACIOĞLU N, ZENGİL H (1997)24-hours variations in the effect of nitrodilators in rat aorta: Lack of influence of endothelium J Pharm Pharmacol 49: 1102-1108,
Abstract
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Özet
ÇAKICI İ, TUNCTAN B, ABACIOĞLU N, KANZIK İ (1993) Epithelium-dependent responses of serotonin in a co-axial bioassay system Eur J Pharmacol 236(1): 97-105
Abstract
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Özet
ABAClOĞLU N, YILDIZOĞLU N, ÖZTÜRK Y (1987) Antibradykinin and antihistaminic actions of haloperidol, chlorpromazine and trifluoperazine-ll: Their ineffectiveness on the bronchoconstrictor action of bradykinin in the in vivo guinea-pig lung in contrast with histamine Pharmacia-JTPA 58(1), 7-10
Abstract
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Özet
KANZIK İ, ZENGİL H, İPEK N, ÇAKICI İ, ABACIOĞLU N, DÖRTLEMEZ H (1991) Synergism between UK 38 485 and ICI 185 282 and the effects of aspirin on this combination aganist digoxin-induced arrhythmias in guinea-pigs Arch Int PharmacodynTher 312 (1/2): 55-65
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Özet
TUNÇTAN B, ALTUĞ S, ULUDAĞ O, ABACIOĞLU N (2005) Contribution of Nitric Oxide and Tumor Necrosis Factor-a to the Effect of Indomethacin on Endotoxin-Induced Mortality FABAD J. Pharm. Sci., 30, 1-6
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Özet
ALTINKURT O, ABACIOĞLU N (1984) Possible effect of vitamin K3 on renin activation J Biochem 9 (2), 40-55 (Turkish / English Abstract)
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Özet
DENİZALTI M, BOZKURT TE, AKPULAT U, SAHIN-ERDEMLI I, ABACIOGLU N (2011) The vasorelaxant effect of hydrogen sulfide is enhanced in streptozotocin-induced diabetic rats. Naunyn Schmiedebergs Arch Pharmacol. 383(5):509-17.
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Özet
ÇAKICI İ, KANZIK İ, ABACIOĞLU N, ZENGİL H (1989) Effect of ovalbumin challenge on reactivity of sensitized guinea-pig trachea smooth muscle J Fac Pharm Gazi, 6 (2), 137-142
Abstract
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Özet
GÜNEY HZ, HODOĞLUGİL U, ULUOĞLU C, GÖRGÜN CZ, ERCAN Z S, ABACIOĞLU N, ZENGİL H (1998) In vitro evidence on the tissue susceptibility rhythms II Biological-time dependent differences in the effect of ?1 and ?2-adrenergic in rat aorta: Influence of endothelium Chronobiol Int 15(2), 159-172
Abstract
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Özet
ABACIOĞLU N, KANZIK İ, ZENGİL H (1988) Antinociceptive potential of ascorbic acid against parabenzoquinone (PBQ) induced writhing test J Fac Pharm Gazi 5(1) : 41-47
Abstract
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Özet
ABACIOĞLU N, DEMİR S, ÇAKICI İ, TUNÇTAN B, KANZIK İ (2000) Role of guanylyl cyclase activation via thiamine in suppressing chemically-induced writhing in mouse Arzneimittel-Forschung Drug Research 50(I): 554-558
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Özet
KANZIK İ, ÇAKICI İ, ERSOY S, ARK M, ABACIOĞLU N, ZENGİL H (1992) Effects of cyclooxygenase and lipoxygenase inhibition on digoxin-induced arrhythmias and haemodynamics in guinea-pigs Pharmacol Res Vol 26 (3), 305-316
Abstract
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Özet
GÜNEY HZ, GÖRGÜN CZ, TUNÇTAN B, ULUDAĞ O, HODOĞLUGİL U, ABACIOĞLU N, ZENGİL H (1998) Circadian rhythm-dependent effects of L-N6 nitroarginine methyl ester (L-NAME) on morphine-induced analgesia Chronobil Int 15(4), 218-223
Abstract
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Özet
ALTINKURT O, ABACIOĞLU N (1984) The interaction between angiotensin II and streptomycine in guinea-pig blood plasma levels and bronchoconstriction and rat arterial blood pressure Pharmacia- JTPA 25:55(3), 155-159 (Turkish / English Abstract)
Abstract
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Özet
TUNÇTAN B, ÇAKICI İ, ABACIOĞLU N, KANZIK İ (1998) Bradykinin-Induced responses via a coaxial bioassay system composed of rat anococcygeus muscle and guinea pig trachea General Pharmacology 30,4, 477-482
Abstract
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Özet
TUNÇTAN B, ALTUĞ S, ULUDAĞ O, DEMİRKAY B, ABACIOĞLU N (2003) Effects of cyclooxygenase inhibitors on nitric oxide production and survival in a mice model of sepsis. Pharmacological Res. 48: 37-48
Abstract
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Özet
KANZIK İ, ÇAKICl İ, DEMİRYÜREK T, ABACIOĞLU N, DÖRTLEMEZ H (1987) Digoxin-induced cardiac toxicity in the anaesthetized guinea- pigs and effect of heparin infusion Arch Int Pharmacodyn 290(2) : 165-172
Abstract
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Özet
ABACIOĞLU N, ERCAN ZS, KANZIK İ, ZENGİL H, DEMİRYÜREK T, TÜRKER RK(1987) Endothelium-dependent relaxing effect of histamine on the isolated guinea-pig main pulmonary artery strips Agents and Actions 22(1/2): 30-35
Abstract
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Özet
ALTUĞ S, UZUN Ö, DEMİRYÜREK AT, ÇAKICI İ, ABACIOĞLU N, KANZIK İ (1999) The role of nitric oxide in digoxin-induced arrhythmias in guinea-pigs Pharmacology & Toxicology 84, 3-8
Abstract
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Özet
TUNCEL N, ABACIOĞLU N, OZANSOY G, TUNCEL M (1985) The polarographic investigation of the effects of adrenaline, noradrenaline and dopamine on striated muscle oxygenation Pharmacia-JTPA 25:55(3), 365-369 (Turkish / English Abstract)
Abstract
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Özet
BAŞGUT B, ADEMOĞLU F GÜRSOY G, ÇAKICI İ, ABACIOĞLU N (2004) Effect of melatonin on the isolated rat anococcygeus muscle FABAD-Journal of Pharmaceutical Sciences 29(4), (Turkish, English abstract)
Abstract
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Özet
DAGLI G, MUTLU EA, ABACIOGLU N (2006) Role of L-Arginine-NO pathway on temporal and gender variation of thiamine analgesia Rev. Clin Pharmacol and Pharmacokin. Int Ed.20:143
Abstract
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Özet
ULUDAĞ O, TUNÇTAN B, GÜNEY HZ, ULUOĞLU C, ALTUĞ S, ZENGİL H, ABACIOĞLU N (1999) Temporal variations in serum nitrite levels in rats and mice Chronobiol Int 16(4), 527-532
Abstract
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Özet
ABAClOĞLU N, YILDIZOĞLU N, ÖZTÜRK Y (1986) Antibradykinin and antihistaminic actions of haloperidol, chlorpromazine and trifluoperazine-l: Studies on the isolated guinea-pig ileum Pharmacia-JTPA 26:57(3), 131-137
Abstract
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Özet
ÇAKICI İ, ABACIOĞLU N, ZENGİL H, KANZIK İ (1992) Biphasic effects of histamine on spontaneously beating rat atria General Pharmacology 23(4) : 705-708
Abstract
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Özet
ADEMOĞLU F, BAŞGUT B, ABACIOĞLU N, ÇAKICI İ (2002) The mechanism of peroxynitrite-induced relaxations on isolated rat anococcygeus muscle Pharmacology 66: 1-4
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Özet
TUNÇTAN B, OKUR H, ÇALIŞIR CH, ABACIOĞLU H, ÇAKICI İ, KANZIK İ, ABACIOĞLU N (1998) Comparison of nitric oxide production by monocyte/macrophages in healthy subjects and patients with active pulmonary tuberculosis Pharmacological Research 37(3), 219-226
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Özet
TUNCEL N, ABAClOĞLU N, TUNCEL M (1986) The polarographic monitoring effects of certain barbituric acid and benzodiazepine derivatives on the oxygenation of skeletal muscle J Fac Pharm Gazi 3 (2), 175-182
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Özet
ULUĞOĞLU C, HODOĞLUGİL U, GÜNEY HZ, GÖRGÜN CZ, ABACIOĞLU N, ZENGİL H (1998) Daily variations in response to papaverine but not theophylline in rat aorta Biol Rhythm 29(4), 343-352
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Özet
BAYTAS S, INCELER N, MAVANEH KF, MO ULUDAG, ABACIOGLU N, GOKCE M (2012) Synthesis of antipyrine/pyridazinone hybrids and investigation of their in vivo analgesic and anti-inflammatory activities Turk J Chem doi:10.3906/kim-1111-29
Abstract
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Özet
ABACIOĞLU N, TUNÇTAN B, ÇAKICI İ, AKBULUT E, ULUDAĞ O, KANZIK İ (2001) The L-arginine/nitric oxide pathway participate in the antinociceptive activity of pyridoxine in mouse. Arzneimittel-Forschung Drug Research 51(II), 832-838.
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Özet
ÇAKICI İ, HURMOĞLU J, TUNÇTAN B, ABACIOĞLU N, KANZIK İ, ŞENER B (1994) Hypoglycaemic effect of Momordica Charantia L extracts in normoglycaemic or cyproheptadine-induced hyperglycaemic mice J Ethnopharmacol 44(2): 94-98
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Özet
ABACIOĞLU N, ÖZMEN R, ÇAKICI İ, TUNÇTAN B, KANZIK İ (2001) Role of L-arginine/nitric oxide pathway in the antinociceptive activities of morphine and mepyramine in mice. Arzneimittel-Forschung Drug Research 51(II), 997-1002.
Abstract
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Özet
ALTINKURT O, ABACIOĞLU N (1984) The possible decreasing effect of H2-receptor blocker cimetidine on angiotensin converting enzyme activity Pharmacia-JTPA 24:51(1), 40-46 (Turkish /English Abstract)
Abstract
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Özet
TUNÇTAN B, WEİGL Y, DOTAN A, PELEG L, ZENGİL H, ASHKENAZİ I, ABACIOĞLU N (2002) Circadian variations of nitric oxide synthase activity in mice tissues. Chronobiology International 19(2), 1-12
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Özet
ULUDAĞ O, TUNÇTAN B, ALTUĞ S, ZENGİL H, ABACIOĞLU N (2007) Twenty-four-hour variation of L-Arginine/nitric Oxide/ Cyclic Guanosine Monophosphate pathway demonstrated by the Mouse visceral pain model Chronobiology International 24 (3): 413-424
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Özet
ÖKSÜZ, S, ÇAKICl, İ, ABACIOĞLU, N, KANZIK, İ (1992) Screening of some ?-lactam antibiotics through electroshock-induced seizure test regarding their potential convulsive adverse reactions J Fac Pharm Gazi 9 (1), 27-38
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CEMRİ M, HODOĞLUGİL U, ULUDAĞ O, BARLAS D, ALTUĞ S, ABACIOĞLU N, DÖRTLEMEZ Ö (2000) Normotansif Bireyler ve Tedavi Edilmemiş Hipertansiflerde Bazı Ambulatuvar Kan Basıncı Değerlerinin Sol Ventrikül Kütle İndeksi ile İlişkisi (Relation Between Some Ambulatory Blood Pressure Parameters and Left Ventricular Mass Index in Normotensive Subjects and Untreated Hypertensive Patients) Türk Kardiyol Dern Arş 28:432-438
Teaching
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Currrent Teaching
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2018 GÜZ
RATIONAL DRUG USE
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2018 GÜZ
PHARMACY REGULATIONS AND DEONTOLOGY
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2018 GÜZ
PHARMACOLOGY I
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2018 GÜZ
PHARMACOLOGY III
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2018 GÜZ
GRADUATION PROJECT
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Teaching History
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2015 BAHAR
CHRONOBIOLOGY,CHRONOPHARMACOLOGY AND CHRONOTHERAPY
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2016 BAHAR
CHRONOBIOLOGY,CHRONOPHARMACOLOGY AND CHRONOTHERAPY
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2017 BAHAR
DRUG INTERACTIONS
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2016 BAHAR
MASTER THESIS
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2015 BAHAR
DRUG INTERACTIONS
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2017 BAHAR
LITERATURE EVALUATION IN PHARMACOLOGY - I
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2016 GÜZ
PHARMACOLOGY OF AUTONOMIC NERVOUS SYSTEM
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2017 BAHAR
Rational Drug Use
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2016 GÜZ
GRADUATION PROJECT
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2017 BAHAR
PHARMACOTHERAPY I
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2017 GÜZ
PHARMACOTHERAPY I
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2017 GÜZ
PHARMACY REGULATIONS AND DEONTOLOGY
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2016 GÜZ
Rational Drug Use
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2016 BAHAR
PHARMACOLOGY II
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2017 BAHAR
CHRONOBIOLOGY,CHRONOPHARMACOLOGY AND CHRONOTHERAPY
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2017 YAZ
PHARMACOLOGY II
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2017 BAHAR
SEMINAR
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2017 GÜZ
PHARMACOLOGY I
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2017 GÜZ
GRADUATION PROJECT
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2017 BAHAR
PHARMACOLOGY OF AUTONOMIC NERVOUS SYSTEM
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2016 GÜZ
SEMINAR
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2015 BAHAR
RESEARCH METHODS IN CLINICAL PHARMACY
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2017 BAHAR
AUTOCOIDS
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2016 GÜZ
RATIONAL DRUG USE
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2016 GÜZ
PHARMACY REGULATIONS AND DEONTOLOGY
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2017 BAHAR
CLINICAL PHARMACOLOGY
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2016 GÜZ
PHARMACOLOGY III
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2016 BAHAR
SEMINAR
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2017 GÜZ
RATIONAL DRUG USE
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2017 BAHAR
PHARMACOLOGY II
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Gallery
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