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Nurettin Abacıoğlu

Pharmacy

Pharmacy – Englısh
Profesör Doktor

Biography

Ankara Üniversitesi Eczacılık Fakültesinden mezun olduktan sonra, yine aynı fakültenin Farmakoloji Anabilim Dalında 1976 yılında, akademik ve mesleki hayatına başladı. 1982 yılında aynı departmanda doktorasını tamamladı. 1984 yılında öğretim görevlisi kadrosuyla Gazi Üniversitesi Eczacılık Fakültesi Farmakoloji Anabilim Dalına geçti. Aynı fakültede 1985 yılında Yardımcı Doçent, 1987 yılında Doçent ve 1992 yılında Profesörlüğe yükseltildi. 1994-1995 yılları arasında bu fakültenin Dekan yardımcılığı görevini sürdürdü. 2002-2016 yılları arasında Farmakoloji Anabilim Dalı Başkanlığı, 2011-2016 yılları arasında da Meslek Bilimleri Bölüm Başkanlığını sürdürdü. Bu fakültenin akademik ve idari çeşitli kurullarında yer aldı. 1984-1990 yılları arasında Türk Eczacıları Birliği Merkez Heyeti Genel Sekreterliği yaptı. Aynı yıllardan başlayarak Devlet Planlama Teşkilatı, ve Sağlık Bakanlığı'nın çeşitli komisyonlarında uzun yıllar görev yaptı. 2013 yılında Türk Eczacıları Birliği Eczacılık Akademisi Hizmet Ödülünü aldı. Bu akademik kurumlarda araştırma makalesi, ulusal ve uluslararası kongre tebliğleri, derlem makaleler ve kitaplar olmak üzere dört yüzden fazla yayın sahibi oldu. 2016 yılında Türk Farmakoloji Derneği meslekte 40. yıl Hizmet Ödülünü aldı ve erken emekli oldu. Şubat 2016 tarihinden bu yana Yakın Doğu Üniversitesi Eczacılık Fakültesine tam zamanlı olarak çalışmaktadır. Halen aynı fakültede öğretim üyeliği ve Farmakoloji Anabilim Dalı Başkanlığı görevlerini sürdürmektedir.

Work Experience

  • Todate 2016

    Farmakoloji Anabilim Dalı Başkanı

    Yakın Doğu Üniversitesi, Eczacılık Fakültesi

  • 2016 2011

    Meslek Bilimleri Bölüm Başkanı

    Gazi Üniversitesi Eczacılık Fakültesi, Meslek Bilimleri Bölümü

  • 2016 2002

    Farmakoloji Anabilim Dalı Başkanı,

    Gazi Üniversitesi Eczacılık Fakültesi, Farmakoloji Anabilim Dalı

  • 1995 1994

    Dekan Yardımcısı

    Gazi Üniversitesi Eczacılık Fakültesi, Gazi Üniversitesi Eczacılık Fakültesi

  • 2016 1992

    Prof. Dr.

    Gazi Üniversitesi Eczacılık fakültesi, Farmakoloji Anabilim Dalı,

  • 1992 1987

    Doç. Dr.

    Gazi Üniversitesi Eczacılık fakültesi, Farmakoloji Anabilim Dalı

  • 1987 1985

    Yrd. Doç. Dr.

    Gazi Üniversitesi Eczacılık Fakültesi, Farmakoloji Anabilim Dalı

  • 1985 1984

    Dr. Öğretim Görevlisi

    Gazi Üniversitesi Eczacılık Fakültesi, Farmakoloji Anabilim Dalı

  • 1984 1982

    Doktor Asistan

    Ankara Üniversitesi Eczacılık Fakültesi, Farmakoloji Anabilim Dalı, Ankara

  • 1982 1976

    Asistan,

    Ankara Üniversitesi Eczacılık Fakültesi, , Farmakoloji Anabilim Dalı, Ankara

Education & Training

  • Ph.D. 1982

    Farmakoloji

    Ankara Üniversitesi

  • Master...

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  • Bachelor1975

    Eczacılık

    Ankara Üniversitesi

Honors, Awards and Grants

  • 2013
    Türk Eczacıları Birliği Eczacılık Akademisi Hizmet Ödülü
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  • 2016
    Türk Farmakoloji derneği Meslekte 40 Yıl Hizmet Ödülü
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Research Summary

Kronobiyoloji, Kronofarmakoloji, Kronoterapi, kardiyovasküler ve Otakoid Farmakoloji, Ağrı Farmakolojisi

Interests

Research Projects

Publications

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Original Article -, Volume -, Issue -, 2000, Pages -

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ABACIOĞLU N, BEDİZ A, ÇAKICI İ, TUNÇTAN B, KANZIK İ (1993) Antinociceptive effects of H1 of H2-antihistaminics in mice General Pharmacology, 24(5), 1173-1176

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HODOĞLUGİL U, AKTUNA-KESKİL Z, GÖRGÜN CZ, ULUOĞLU C, ABACIOĞLU N, ZENGİL H (1999) Effect of time on endothelium-dependent relaxations in mice and rat thoracic aortas Biol Rhythm Res 30(4), 434-444

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MEMİŞ A, UZUN Ö, ULUSOY E, ABACIOĞLU N, KANZIK İ (1994) Ceftriaxon for the therapy of chronic bacterial prostatitis Therapy 49: 49

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SUNAL R, KANZIK İ, ABACIOĞLU N (1985) Hypothermic effect of cimetidine in rats Turkish J Pharmacol Clin Res 3(1,2), 83-86

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ABACIOĞLU N, TUNÇTAN B, AKBULUT E, ÇAKICI İ (2000) Participation of the components of L-arginine/nitric oxide/cGMP cascade by p-benzoquinone-induced nociceptive processes in the mouse Life Sciences 67(10): 1127-1137

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ALTINKURT O, ABACIOĞLU N Non-competitive inhibition of angiotensin II and PGE2 on guinea-pig ileum with streptomycine, vit K3 and rutin Arzneim-Forsch Drug Res 30 (1) 4, 610-613 (1980)

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HENGİRMAN, S, UZUN, Ö, TERZİ, C, CETE, M, ABACIOĞLU, N, KANZIK, İ (1992) Comparison of serum, gallbladder wall and bile concentrations of cefazolin and cefoxitin in elective biliary surgery J Fac Pharm Gazi 9 (1), 19-26

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GÜNEY HZ, ULUOĞLU C, HODOĞLUGİL U, GÖRGÜN CZ, YAMANOĞLU T, ABACIOĞLU N, ZENGİL H (1999) Biological-time dependent differences in effect of verapamil on rat aorta and influence of endothelium Chronobiol Int, 16(6), 779-787

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GÖRGÜN CZ, HODOĞLUGİL U, KESKİL RZ, ERCAN ZS, ABACIOĞLU N, ZENGİL H (1998) In vitro evidence on the tissue susceptibility rhythm I Temporal variations in the effect of potassium chloride and phenylephrine in rat aorta Chronobiol Int 15(2), 39-48

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ALTIPARMAK H, ÇAKICI İ, KANZIK İ, ABACIOĞLU N (1992) Implementation and validation of probit transformation in linearizing dose-response curves and statistical analysis J Fac Pharm Gazi 9(2): 107-113

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TUNÇTAN, B, ULUDAĞ, O, ALTUĞ, S, ABACIOĞLU, N (1998) Effects of nitric oxide synthase inhibition in lipopolysaccharide-induced sepsis in mice Pharmacological Research, Vol 38,(5),405-411

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ERDEMOGLU N, TURAN NN, AKKOL EK, SENER B, ABACIOGLU N (2009) Estimation of anti-inflammatory, antinociceptive and antioxidant activities of Arctium minus (Hill) Bernh. ssp. minus. J Ethnopharmacol. 21;121(2):318-23.

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ÇAKICl İ, ULUĞ HY, İNCİ S, TUNÇTAN B, ABACIOĞLU N, KANZIK, İ, ŞENER, B (1997) Antinociceptive effect of some Amaryllidaceae plants J Pharm Pharmacol 49, 828-830

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ALAGÖL H, DİNÇ S, BASGUT B, ABACIOĞLU N (2007) Temporal variation in the recovery from impairment in adriamycin-induced wound healing in rats Journal of Circadian Rhythms 5:6, doi:10. 1186/1740-3391-5-6

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ÇAKICI İ, ZENGİL H, ABACIOĞLU N, KANZIK İ (1989) The temperature dependent specific desensitization in the rat anococcygeus muscle to angiotensin II Pharmacology, 39(2) : 115-120

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ALTINKURT O, ABACIOĞLU N (1984) The possible decompensation process depend on plasma angiotensin degredation in electroshock AEOB 6: 1, 36-45 (Turkish / English Abstract)

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TUNÇTAN B, ALTUĞ S, ULUDAĞ O, ABACIOĞLU N (2000) Effects of econazole on receptor-operated and depolarization-induced contractions in rat isolated aorta Life Sciences 67: 2393-2401

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KANZIK İ, DEMİRYÜREK T, ZENGİL H, ABACIOĞLU N, DÖRTLEMEZ H (1988) Effects of thromboxane synthetase inhibitör (UK 38 485) and thromboxane receptor antagonist (iCI 185, 282) on digoxin-induced arrhythmias in anaesthetised guinea-pigs Clin Exp Pharmacol Physiol 15, 925-937

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TUNÇTAN B, ALTUĞ S, ULUDAĞ O, ABACIOĞLU N (2000) Time-dependent variation in serum nitrite, 6-k-PGF1? and TxB2 levels induced by lipopolysaccharide in mice Biological Rhythm Research 31(49: 514 )

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AKAR F, ARK M, UYDEŞ BS, SOYSAL ME, SARAÇOĞLU F, ABACIOĞLU N, VOORDE J Van De, KANZIK İ (1994) Nitric oxide production by human umbilical vessels in severe preeclampsia Journal of Hypertension 12, 1235-1241

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ÇAKICl İ, MATARACI N, ERSOY S, TUNÇTAN B, ABACIOĞLU N, KANZIK İ (1995) Effects of PAF antagonists WEB 2086 and BN 50730 on digoxin-induced arrhythmias Pharmacol Toxicol 76(6): 343-347

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HODOĞLUGİL U, ULUOĞLU C, GÜNEY HZ, GÖRGÜN CZ, ERCAN ZS, ABACIOĞLU N, ZENGİL H (1997)24-hours variations in the effect of nitrodilators in rat aorta: Lack of influence of endothelium J Pharm Pharmacol 49: 1102-1108,

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ÇAKICI İ, TUNCTAN B, ABACIOĞLU N, KANZIK İ (1993) Epithelium-dependent responses of serotonin in a co-axial bioassay system Eur J Pharmacol 236(1): 97-105

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ABAClOĞLU N, YILDIZOĞLU N, ÖZTÜRK Y (1987) Antibradykinin and antihistaminic actions of haloperidol, chlorpromazine and trifluoperazine-ll: Their ineffectiveness on the bronchoconstrictor action of bradykinin in the in vivo guinea-pig lung in contrast with histamine Pharmacia-JTPA 58(1), 7-10

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KANZIK İ, ZENGİL H, İPEK N, ÇAKICI İ, ABACIOĞLU N, DÖRTLEMEZ H (1991) Synergism between UK 38 485 and ICI 185 282 and the effects of aspirin on this combination aganist digoxin-induced arrhythmias in guinea-pigs Arch Int PharmacodynTher 312 (1/2): 55-65

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TUNÇTAN B, ALTUĞ S, ULUDAĞ O, ABACIOĞLU N (2005) Contribution of Nitric Oxide and Tumor Necrosis Factor-a to the Effect of Indomethacin on Endotoxin-Induced Mortality FABAD J. Pharm. Sci., 30, 1-6

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ALTINKURT O, ABACIOĞLU N (1984) Possible effect of vitamin K3 on renin activation J Biochem 9 (2), 40-55 (Turkish / English Abstract)

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DENİZALTI M, BOZKURT TE, AKPULAT U, SAHIN-ERDEMLI I, ABACIOGLU N (2011) The vasorelaxant effect of hydrogen sulfide is enhanced in streptozotocin-induced diabetic rats. Naunyn Schmiedebergs Arch Pharmacol. 383(5):509-17.

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ÇAKICI İ, KANZIK İ, ABACIOĞLU N, ZENGİL H (1989) Effect of ovalbumin challenge on reactivity of sensitized guinea-pig trachea smooth muscle J Fac Pharm Gazi, 6 (2), 137-142

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GÜNEY HZ, HODOĞLUGİL U, ULUOĞLU C, GÖRGÜN CZ, ERCAN Z S, ABACIOĞLU N, ZENGİL H (1998) In vitro evidence on the tissue susceptibility rhythms II Biological-time dependent differences in the effect of ?1 and ?2-adrenergic in rat aorta: Influence of endothelium Chronobiol Int 15(2), 159-172

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ABACIOĞLU N, KANZIK İ, ZENGİL H (1988) Antinociceptive potential of ascorbic acid against parabenzoquinone (PBQ) induced writhing test J Fac Pharm Gazi 5(1) : 41-47

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ABACIOĞLU N, DEMİR S, ÇAKICI İ, TUNÇTAN B, KANZIK İ (2000) Role of guanylyl cyclase activation via thiamine in suppressing chemically-induced writhing in mouse Arzneimittel-Forschung Drug Research 50(I): 554-558

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KANZIK İ, ÇAKICI İ, ERSOY S, ARK M, ABACIOĞLU N, ZENGİL H (1992) Effects of cyclooxygenase and lipoxygenase inhibition on digoxin-induced arrhythmias and haemodynamics in guinea-pigs Pharmacol Res Vol 26 (3), 305-316

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GÜNEY HZ, GÖRGÜN CZ, TUNÇTAN B, ULUDAĞ O, HODOĞLUGİL U, ABACIOĞLU N, ZENGİL H (1998) Circadian rhythm-dependent effects of L-N6 nitroarginine methyl ester (L-NAME) on morphine-induced analgesia Chronobil Int 15(4), 218-223

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ALTINKURT O, ABACIOĞLU N (1984) The interaction between angiotensin II and streptomycine in guinea-pig blood plasma levels and bronchoconstriction and rat arterial blood pressure Pharmacia- JTPA 25:55(3), 155-159 (Turkish / English Abstract)

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TUNÇTAN B, ÇAKICI İ, ABACIOĞLU N, KANZIK İ (1998) Bradykinin-Induced responses via a coaxial bioassay system composed of rat anococcygeus muscle and guinea pig trachea General Pharmacology 30,4, 477-482

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TUNÇTAN B, ALTUĞ S, ULUDAĞ O, DEMİRKAY B, ABACIOĞLU N (2003) Effects of cyclooxygenase inhibitors on nitric oxide production and survival in a mice model of sepsis. Pharmacological Res. 48: 37-48

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KANZIK İ, ÇAKICl İ, DEMİRYÜREK T, ABACIOĞLU N, DÖRTLEMEZ H (1987) Digoxin-induced cardiac toxicity in the anaesthetized guinea- pigs and effect of heparin infusion Arch Int Pharmacodyn 290(2) : 165-172

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ABACIOĞLU N, ERCAN ZS, KANZIK İ, ZENGİL H, DEMİRYÜREK T, TÜRKER RK(1987) Endothelium-dependent relaxing effect of histamine on the isolated guinea-pig main pulmonary artery strips Agents and Actions 22(1/2): 30-35

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ALTUĞ S, UZUN Ö, DEMİRYÜREK AT, ÇAKICI İ, ABACIOĞLU N, KANZIK İ (1999) The role of nitric oxide in digoxin-induced arrhythmias in guinea-pigs Pharmacology & Toxicology 84, 3-8

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TUNCEL N, ABACIOĞLU N, OZANSOY G, TUNCEL M (1985) The polarographic investigation of the effects of adrenaline, noradrenaline and dopamine on striated muscle oxygenation Pharmacia-JTPA 25:55(3), 365-369 (Turkish / English Abstract)

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BAŞGUT B, ADEMOĞLU F GÜRSOY G, ÇAKICI İ, ABACIOĞLU N (2004) Effect of melatonin on the isolated rat anococcygeus muscle FABAD-Journal of Pharmaceutical Sciences 29(4), (Turkish, English abstract)

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DAGLI G, MUTLU EA, ABACIOGLU N (2006) Role of L-Arginine-NO pathway on temporal and gender variation of thiamine analgesia Rev. Clin Pharmacol and Pharmacokin. Int Ed.20:143

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ULUDAĞ O, TUNÇTAN B, GÜNEY HZ, ULUOĞLU C, ALTUĞ S, ZENGİL H, ABACIOĞLU N (1999) Temporal variations in serum nitrite levels in rats and mice Chronobiol Int 16(4), 527-532

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ABAClOĞLU N, YILDIZOĞLU N, ÖZTÜRK Y (1986) Antibradykinin and antihistaminic actions of haloperidol, chlorpromazine and trifluoperazine-l: Studies on the isolated guinea-pig ileum Pharmacia-JTPA 26:57(3), 131-137

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ÇAKICI İ, ABACIOĞLU N, ZENGİL H, KANZIK İ (1992) Biphasic effects of histamine on spontaneously beating rat atria General Pharmacology 23(4) : 705-708

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ADEMOĞLU F, BAŞGUT B, ABACIOĞLU N, ÇAKICI İ (2002) The mechanism of peroxynitrite-induced relaxations on isolated rat anococcygeus muscle Pharmacology 66: 1-4

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TUNÇTAN B, OKUR H, ÇALIŞIR CH, ABACIOĞLU H, ÇAKICI İ, KANZIK İ, ABACIOĞLU N (1998) Comparison of nitric oxide production by monocyte/macrophages in healthy subjects and patients with active pulmonary tuberculosis Pharmacological Research 37(3), 219-226

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TUNCEL N, ABAClOĞLU N, TUNCEL M (1986) The polarographic monitoring effects of certain barbituric acid and benzodiazepine derivatives on the oxygenation of skeletal muscle J Fac Pharm Gazi 3 (2), 175-182

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ULUĞOĞLU C, HODOĞLUGİL U, GÜNEY HZ, GÖRGÜN CZ, ABACIOĞLU N, ZENGİL H (1998) Daily variations in response to papaverine but not theophylline in rat aorta Biol Rhythm 29(4), 343-352

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BAYTAS S, INCELER N, MAVANEH KF, MO ULUDAG, ABACIOGLU N, GOKCE M (2012) Synthesis of antipyrine/pyridazinone hybrids and investigation of their in vivo analgesic and anti-inflammatory activities Turk J Chem doi:10.3906/kim-1111-29

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ABACIOĞLU N, TUNÇTAN B, ÇAKICI İ, AKBULUT E, ULUDAĞ O, KANZIK İ (2001) The L-arginine/nitric oxide pathway participate in the antinociceptive activity of pyridoxine in mouse. Arzneimittel-Forschung Drug Research 51(II), 832-838.

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ÇAKICI İ, HURMOĞLU J, TUNÇTAN B, ABACIOĞLU N, KANZIK İ, ŞENER B (1994) Hypoglycaemic effect of Momordica Charantia L extracts in normoglycaemic or cyproheptadine-induced hyperglycaemic mice J Ethnopharmacol 44(2): 94-98

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ABACIOĞLU N, ÖZMEN R, ÇAKICI İ, TUNÇTAN B, KANZIK İ (2001) Role of L-arginine/nitric oxide pathway in the antinociceptive activities of morphine and mepyramine in mice. Arzneimittel-Forschung Drug Research 51(II), 997-1002.

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ALTINKURT O, ABACIOĞLU N (1984) The possible decreasing effect of H2-receptor blocker cimetidine on angiotensin converting enzyme activity Pharmacia-JTPA 24:51(1), 40-46 (Turkish /English Abstract)

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TUNÇTAN B, WEİGL Y, DOTAN A, PELEG L, ZENGİL H, ASHKENAZİ I, ABACIOĞLU N (2002) Circadian variations of nitric oxide synthase activity in mice tissues. Chronobiology International 19(2), 1-12

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ULUDAĞ O, TUNÇTAN B, ALTUĞ S, ZENGİL H, ABACIOĞLU N (2007) Twenty-four-hour variation of L-Arginine/nitric Oxide/ Cyclic Guanosine Monophosphate pathway demonstrated by the Mouse visceral pain model Chronobiology International 24 (3): 413-424

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ÖKSÜZ, S, ÇAKICl, İ, ABACIOĞLU, N, KANZIK, İ (1992) Screening of some ?-lactam antibiotics through electroshock-induced seizure test regarding their potential convulsive adverse reactions J Fac Pharm Gazi 9 (1), 27-38

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CEMRİ M, HODOĞLUGİL U, ULUDAĞ O, BARLAS D, ALTUĞ S, ABACIOĞLU N, DÖRTLEMEZ Ö (2000) Normotansif Bireyler ve Tedavi Edilmemiş Hipertansiflerde Bazı Ambulatuvar Kan Basıncı Değerlerinin Sol Ventrikül Kütle İndeksi ile İlişkisi (Relation Between Some Ambulatory Blood Pressure Parameters and Left Ventricular Mass Index in Normotensive Subjects and Untreated Hypertensive Patients) Türk Kardiyol Dern Arş 28:432-438

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ALTUĞ S, ULUDAĞ O, TUNÇTAN B, ZENGİL H, ABACIOĞLU N (2006) Biological time-dependent difference in effect of peroxynitrite demostrated by the Mouse hot plate pain model Chronobiology International 23 (3): 583-591

Teaching

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Currrent Teaching

  • 2018 BAHAR

    PHARMACOLOGY I

  • 2018 BAHAR

    PHARMACOLOGY II

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  • 2018 BAHAR

    CHRONOBIOLOGY,CHRONOPHARMACOLOGY AND CHRONOTHERAPY

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Teaching History

  • 2016 BAHAR

    MASTER THESIS

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  • 2017 BAHAR

    DRUG INTERACTIONS

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  • 2015 BAHAR

    CHRONOBIOLOGY,CHRONOPHARMACOLOGY AND CHRONOTHERAPY

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  • 2018 GÜZ

    PHARMACOVIGILANCE PRACTICE-I

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  • 2016 GÜZ

    PHARMACOLOGY OF AUTONOMIC NERVOUS SYSTEM

  • 2017 BAHAR

    LITERATURE EVALUATION IN PHARMACOLOGY - I

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  • 2017 BAHAR

    Rational Drug Use

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  • 2016 GÜZ

    GRADUATION PROJECT

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  • 2018 GÜZ

    PHARMACOVİGİLANCE PRACTİCE-II

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  • 2017 BAHAR

    PHARMACOTHERAPY I

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  • 2017 GÜZ

    PHARMACOTHERAPY I

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  • 2016 GÜZ

    Rational Drug Use

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  • 2016 BAHAR

    PHARMACOLOGY II

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  • 2017 BAHAR

    PHARMACOLOGY OF AUTONOMIC NERVOUS SYSTEM

  • 2016 GÜZ

    SEMINAR

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  • 2018 GÜZ

    PHARMACOECONOMY

  • 2017 YAZ

    PHARMACOLOGY II

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  • 2017 BAHAR

    SEMINAR

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  • 2016 GÜZ

    RATIONAL DRUG USE

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  • 2016 GÜZ

    PHARMACOLOGY III

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  • 2016 BAHAR

    SEMINAR

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  • 2016 BAHAR

    CHRONOBIOLOGY,CHRONOPHARMACOLOGY AND CHRONOTHERAPY

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  • 2018 GÜZ

    PHARMACOLOGY III

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  • 2015 BAHAR

    DRUG INTERACTIONS

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  • 2015 BAHAR

    RESEARCH METHODS IN CLINICAL PHARMACY

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  • 2017 BAHAR

    AUTOCOIDS

  • 2017 GÜZ

    PHARMACOLOGY I

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  • 2017 GÜZ

    GRADUATION PROJECT

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  • 2018 GÜZ

    GRADUATION PROJECT

    -

  • 2016 GÜZ

    PHARMACY REGULATIONS AND DEONTOLOGY

    -

  • 2017 BAHAR

    CLINICAL PHARMACOLOGY

    -

  • 2017 BAHAR

    CHRONOBIOLOGY,CHRONOPHARMACOLOGY AND CHRONOTHERAPY

    -

  • 2017 GÜZ

    PHARMACY REGULATIONS AND DEONTOLOGY

    -

  • 2018 GÜZ

    PHARMACY REGULATIONS AND DEONTOLOGY

    -

  • 2018 GÜZ

    PHARMACOLOGY I

    -

  • 2017 GÜZ

    RATIONAL DRUG USE

    -

  • 2018 GÜZ

    RATIONAL DRUG USE

    -

  • 2017 BAHAR

    PHARMACOLOGY II

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Contact & Meet Me

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  •    office: 123
  •    nurettin.abacioglu@neu.edu.tr
  •    nurettin.abacioglu@neu.edu.tr
  •   
  •   
  •   

At My Office

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