Work Experience

  • Todate 2012

    Dr.

    Diş Hekimliği Fakültesi, Ağız, Diş ve Çene Cerrahisi A.D.

Education & Training

  • Ph.D. 2016

    Ağız, Diş ve Çene Cerrahisi

    Yakın Doğu Üniversitesi

  • Master...

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  • Bachelor2011

    Diş Hekinliği

    Hacettepe Üniversitesi

Honors, Awards and Grants

Research Projects

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    Sıçanlarda Zymosan ile Oluşturulan Temporomandibuler Eklem Artrit Modelinde Melatonin ve 5-Metoksitriptofol’un etkilerinin histolojik ve radyolojik yönden araştırılması, 2015.

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Paresthesia of the Nervus Alveolaris Inferior due to Impacted Teeth: 2 Case Report

Conference Paper 20th International Taoms Congress, Antalya, Turkey, 19-23 May 2013, Volume -, Issue -, 2013, Pages -

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Maksillar Adenoid Kistik Karsinoma: Olgu Raporu

Conference Paper Oral Diagnoz ve Maksillofasiyal Radyoloji Derneği 6. Ulusal Sempozyumu ve 1. Uluslararası Katılımlı Kongresi, 2014, Volume -, Issue -, 2014, Pages -

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Delayed Permanent Tooth Eruption Due to the Previous Trauma and Treatment Procedure.

Conference Paper International Journal of Pediatric Dentistry, Volume Volume 25, Issue Issue Supplement s1 , 2015, Pages 157

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Evaluation of different fixation methods in mandibular angle fractures with finite element method.

Conference Paper TDA 21st International Dental Congress (TDA 2015) 28 May-30 May 2015 Istanbul, Turkey., Volume -, Issue -, 2015, Pages -

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Traumatic Bone Cyst: Case Report

Conference Paper 21th TDA International Dental Congress, Istanbul, 28-30 May 2015., Volume -, Issue -, 2015, Pages -

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Inactive Implant Periapical Lesion: A Case Report.

Conference Paper ACBİD, 10. Uluslararsı Kongresi, 11-15 Mayıs 2016., Volume -, Issue -, 2016, Pages -

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Meziodens ve diastema: olgu sunumu

Conference Paper TDA 22th International Dental Congress (TDA 2016) 19-21 May 2016 İzmir, Turkey., Volume -, Issue -, 2016, Pages -

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Compound Odontoma Located Between Deciduous And Permanent Canine: Case Report

Conference Paper 22nd International Dental Congress Of Turkish Dental Association (TDA 2016), 19-21 May 2016., Volume -, Issue -, 2016, Pages -

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https://www.researchgate.net/profile/Ayliz_Velioglu_Ogunc/publication/303018054_Effects_of_melatonin_and_5-methoxytryptophol_on_synovial_inflammation_in_the_zymosan-induced_rheumatoid_arthritis_in_rats/links/5735a35b08ae298602e073f5.pdf

General Publication Effects of melatonin and 5-methoxytryptophol on synovial inflammation in the zymosan-induced rheumatoid arthritis in rats, 2016

Abstract


Özet

Effects of Melatonin and 5-Methoxytryptophol on Synovial Inflammation in the Zymosan-Induced Rheumatoid Arthritis in Rats.

Original Article Int J Clin Exp Med. , Volume 9, Issue 4, 2016, Pages 7137-7144

Abstract

The aim of this study is the investigation of synoviocytes, cytokines and metalloproteinases in the synovial inflammation model which is created by zymosan application to temporomandibular joint (TMJ) and effects of pineal hormones melatonin (MEL) and 5-methoxytryptophol (5-MTX) on these parameters. 200-250 g Wistar albino rats of both sexes were used for modeling arthritis in this study. Arthritis model was created by intraarticularly (i.a.) injecting 2 mg zymosan in 40 ml saline into the left temporamandibular joint of the rats while the sham group was created by only injecting 40 ml saline solution (intraarticulary). MEL and 5-MTX administration was made intraperitoneal before zymosan injection. 6 hours after zymosan or saline administration of MEL and 5-MTX the synovial fluid was collected from the animals and the synovial membrane was collected for histological assessment. The administration of zymosan increased the release of IL-1ß and TNF? and the activity of metalloproteinases (MMM-9) and metalloproteinases-2 (MMP-2) and with this administration values got closer to the sham group. The histological evaluation showed significant increase in the intensity of synoviocytes that arose in the inflammation was found to subside. In conclusion, MEL and 5-MTX reducing inflammation in arthritis suggests these agents might constitute a new therapeutic principle clinically.


Özet

Currrent Teaching

  • 2018 AKADEMİK YILI

    ORAL SURGERY

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  • 2018 GÜZ

    APPLICATION PERIOD

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  • 2018 AKADEMİK YILI

    BASIC LIFE SUPPORT

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Teaching History

  • 2016 BAHAR

    APPLICATION PERIOD

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  • 2017 AKADEMİK YILI

    BASIC LIFE SUPPORT

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  • 2017 GÜZ

    APPLICATION PERIOD

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  • 2017 BAHAR

    APPLICATION PERIOD

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