Work Experience

  • Todate 2011

    Araştırma Görevlisi

    Farmasötik Botanik- Farmakognozi, Eczacılık Fakültesi

Education & Training

  • Ph.D. ..

    -

    -

  • Master2014

    Farmasötik Botanik

    Yakın Doğu Üniversitesi

  • Bachelor2011

    Biyoloji

    Hacettepe Üniversitesi

Honors, Awards and Grants

Research Projects

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    Özkum Yavuz, D., Yiğit Hanoğlu, D., Hanoğlu, A., Demirci,B., Başer, K.H.C., Çalış, İ., Kıbrıs'ın Kuzeyinde Doğal Olarak Yetişen Endemik Sideritis cypria POST Bitkisinin Fitokimyasal ve Biyolojik Aktivite Çalışmaları, SAG-1-2016-044, Bilimsel Araştırmalar Projeleri (BAP)- 2016.

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    Çalış, İ., Özkum Yavuz, D., Hanoğlu, A., Yiğit Hanoğlu, D., Demirci,B., Başer, K.H.C., Kıbrıs'ın Kuzey'inde Yetişen Üç Phlomis Türü Üzerine Fitokimyasal ve Biyolojik Araştırmalar, SAG-1-2016-043, Bilimsel Araştırmalar Projeleri (BAP)- 2016.

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    Meriçli, AH., Meriçli, F., Özkum Yavuz, D., Hanoğlu, A., Hanoğlu Yiğit, D., Kuzey Kıbrıs’ta Yetişen Colchicum pusillum Türünün Alkaloitleri, SAG-2-2016-030, Bilimsel Araştırmalar Projeleri (BAP)- 2016.

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    Özkum Yavuz, D, H.K. Süer, Hanoğlu, A. , Yiğit Hanoğlu, D., Güvenir, M., K.K.T.C.’de Doğal Olarak Yetişen Thymus capitatus (tülümbe/kekik) Bitkisinin Uçucu Yağının Disk Difüzyon Yöntemiyle Antiülserojenik aktivitesinin Saptanması, 2015.

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    Özkum Yavuz,D., Serakıncı, N., Yiğit Hanoğlu, D., Hanoğlu, A., Mavis, M., Demirci, B., Başer, K.H.C., KKTCde Doğal Olarak Yetişen Lamiaceae Familyasına ait Bazı Türlerin Uçucu Yağlarının GC-MS Analizleri ve Biyolojik ve Antikanser Aktivitelerinin Belirlenmesi, SAG-1-2016-040, Bilimsel Araştırmalar Projeleri (BAP)- 2016

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Chemical Composition and antimicrobial activity of the essential oil of Sideritis cypria Post endemic in Northern Cyprus

Original Article Journal of Essential oil Research, Volume -, Issue -, 2016, Pages 1-5

Abstract

In this study, chemical composition and antimicrobial activity of the essential oil of Sideritis cypria, which is an endemic taxon in Northern Cyprus, were investigated. The essential oil obtained by hydrodistillation were analyzed by gas chromatography (GC) and gas chromatography-mass spectrometry (GC-MS). In general, the GC and GC-MS analysis illustrated that fifty compounds were identified representing 96.9% of the oil. Major components were epi-cubebol (11.9%), trans-piperitol (8.9%) and pinene (8.1%), respectively. The antimicrobial activity of the essential oil was tested by disc diffusion method against Pseudomonas aeruginosa (ATCC 27853), Escherichia coli (ATCC 25922), Bacillus cereus (ATCC 10876), Staphylococcus aureus (ATCC 25923) bacteria and Candida albicans (ATCC 90028) yeast. The results showed that the inhibition zone of S. cypria essential oil against C. albicans at maximum dose (10 µl) was higher than positive control Nystatin. The oil showed similar inhibitory zone to that of the positive control (TMP-SMX) against B. cereus at maximum dosage 10 µl. In addition, the inhibitory effect of the oil against E. coli measured only at the 10 µl as 10.33 ± 0.58. Furthermore, the inhibition zones against S. aureus was ranged from 9.00 ± 2.00 to 24.00 ± 1.73 while P. aeruginosa was found to be resistant in all doses.


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